Results 161 to 170 of about 26,045 (258)

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Coral growth, retraction, defense, and regenerative strategies revealed by live microCT. [PDF]

Sci Adv
Araslanova K, Kaiser M, Fetisov A, Gavrik D, Zikmund T, Abed-Navandi D, Katovský K, Kaiser J, Adameyko I.   +8 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Origin of Earth's hydrogen and carbon constrained by their core-mantle partitioning and bulk Earth abundance. [PDF]

Nat Commun
Tsutsumi Y, Sakamoto N, Hirose K, Mita S, Yokoo S, Hsu H, Yurimoto H.   +6 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Geomorphological changes of natural and engineered vegetated foredunes since completion of Kustwerk Katwijk. [PDF]

Sci Rep
Spears A, Apraku C, Whalin RW.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Commentary: Anticoagulant outcomes in managing tumor thrombus: a systematic review. [PDF]

Front Oncol
Cordeanu EM, Stephan D.
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Land use change and soil salinization in the Sundarbans: a machine-learning based analysis of long-term transformation and future projections. [PDF]

Environ Monit Assess
Mandal UK, Ghosh A, Karim F, Mallick S, Nayak DB, Bhutia RN, Bhardwaj AK, Lama TD, Burman D, Choudhury P, Mahanta KK, Raut S, Mandal S, Mainuddin M.   +13 more
europepmc   +1 more source