Results 91 to 100 of about 40,120 (302)

Revealing the accretion disc corona in Mrk 335 with multi-epoch X-ray spectroscopy

open access: yes, 2015
Active galactic nuclei host an accretion disc with an X-ray producing corona around a supermassive black hole. In bright sources, such as the Seyfert 1 galaxy Mrk 335, reflection of the coronal emission off the accretion disc has been observed ...
Ballantyne, D. R., Keek, L.
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Circular orbits of accretion flow around charged black hole coupled with a nonlinear electrodynamics field

open access: yesEuropean Physical Journal C: Particles and Fields
This study investigates the particle’s geodesic motion and accretion around the spherically symmetric Reissner–Nordström black hole coupled with a nonlinear electrodynamics field.
H. Rehman   +4 more
doaj   +1 more source

Accretion on to Magnetic White Dwarfs

open access: yesEPJ Web of Conferences, 2014
The Magnetic Cataclysmic Variables (MCVs) are close interacting binaries where mass is transferred from a late type secondary star to a magnetic white dwarf.
Wickramasinghe Dayal
doaj   +1 more source

A Changing-Look AGN to Be Probed by X-ray Polarimetry

open access: yesGalaxies, 2018
Active galactic nuclei (AGN) produce the highest intrinsic luminosities in the Universe from within a compact region. The central engine is thought to be powered by accretion onto a supermassive black hole.
Beatriz Agís-González   +2 more
doaj   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao   +10 more
wiley   +1 more source

Confrontation of the Magnetically Arrested Disc Scenario with Observations of FR II Sources

open access: yesFrontiers in Astronomy and Space Sciences, 2017
The main aim of our work was to check whether powers of jets in FR II radio galaxies (RGs) and quasars (QSOs) can be reproduced by the Magnetically Arrested Disc (MAD) scenario.
Katarzyna Rusinek, Marek Sikora
doaj   +1 more source

Iron line profiles and self-shadowing from relativistic thick accretion discs

open access: yes, 2008
We present Fe Kalpha line profiles from and images of relativistic discs with finite thickness around a rotating black hole using a novel code. The line is thought to be produced by iron fluorescence of a relatively cold X-ray illuminated material in the
Abramowicz   +64 more
core   +1 more source

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini   +13 more
wiley   +1 more source

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