Results 21 to 30 of about 790,437 (254)
This studi aims to test the influence of capital spending on economic accretion mediated by Original Local Government Revenue (PAD) in districts/cities in Bakorwil 1 Madiun in 2012 - 2022.
Nurharibnu Wibisono+3 more
semanticscholar +1 more source
We compare different examples of spherical accretion onto a gravitating mass. Limiting cases include the accretion of a collisionally dominated fluid and the accretion of collisionless particles. We derive expressions for the accretion rate and density profile for semi-collisional accretion which bridges the gap between these limiting cases.
arxiv +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Continuously time variable sources are often characterized by their power spectral density and flux distribution. These quantities can undergo dramatic changes over time if the underlying physical processes change. However, some changes can be subtle and
Ghez, A. M.+3 more
core +1 more source
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze+3 more
wiley +1 more source
The credit spread curve. I: Fundamental concepts, fitting, par-adjusted spread, and expected return [PDF]
The notion of a credit spread curve is fundamental in fixed income investing, but in practice it is not `given' and needs to be constructed from bond prices either for a particular issuer, or for a sector rating-by-rating. Rather than attempting to fit spreads -- and as we discuss here, the Z-spread is unsuitable -- we fit parametrised survival curves.
arxiv
We investigate the dynamical interaction of a central star cluster surrounding a super-massive black hole and a central accretion disk. The dissipative force acting on stars in the disk leads to an enhanced mass flow towards the super-massive black hole ...
Andreas Just+33 more
core +1 more source
High‐grade serous ovarian cancer (HGSOC) is the most common and aggressive type of ovarian cancer with urgent need for new treatment strategies. This study evaluates plasma‐activated media (PAM) as a novel treatment for HGSOC, showing its ability to selectively induce oxidative stress and apoptosis in HGSOC cell lines, patient ascites cells and primary
Lorena T. Davies+9 more
wiley +1 more source
West Irondequoit Central School District and West Irondequoit Teachers Association [PDF]
In the matter of the fact-finding between the West Irondequoit Central School District, employer, and the West Irondequoit Teachers Association, union. PERB case no. M2013-095. Before: Stephen P.
LaLonde, Stephen P
core +1 more source
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren+4 more
wiley +1 more source