Results 21 to 30 of about 779,827 (233)

West Irondequoit Central School District and West Irondequoit Teachers Association [PDF]

, 2014
In the matter of the fact-finding between the West Irondequoit Central School District, employer, and the West Irondequoit Teachers Association, union. PERB case no. M2013-095. Before: Stephen P.
LaLonde, Stephen P
core   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

On the Influence of Minor Mergers on the Radial Abundance Gradient in Disks of Milky Way-like Galaxies

, 2015
We investigate the influence of stellar migration caused by minor mergers (mass ratio from 1:70 to 1:8) on the radial distribution of chemical abundances in the disks of Milky Way-like galaxies during the last four Gyr.
Berczik, Peter, Grebel, Eva K., Just, Andreas, Pilyugin, Leonid S., Zinchenko, Igor A.   +4 more
core   +1 more source

The JCMT Transient Survey: An Extraordinary Submillimetre Flare in the T Tauri Binary System JW 566 [PDF]

, 2018
The binary T Tauri system JW 566 in the Orion Molecular Cloud underwent an energetic, short-lived flare observed at submillimetre wavelengths by the SCUBA-2 instrument on 26 November 2016 (UT).
Bell, Graham S., Bower, Geoffrey C., Chen, Wen-Ping, Forbrich, Jan, Hacar, Alvaro, Herczeg, Gregory J., Johnstone, Doug, Lalchand, Bhavana, Lee, Jeong-Eun, Mairs, Steve   +9 more
core   +4 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Supermassive Black Holes in Galactic Nuclei with Tidal Disruption of Stars: Paper II - Axisymmetric Nuclei

, 2015
Tidal Disruption of stars by supermassive central black holes from dense rotating star clusters is modelled by high-accuracy direct N-body simulation.
Berczik, Peter, Spurzem, Rainer, Zhong, Shiyan   +2 more
core   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Kinematically Detected Halo Streams

, 2016
Clues to the origins and evolution of our Galaxy can be found in the kinematics of stars around us. Remnants of accreted satellite galaxies produce over- densities in velocity-space, which can remain coherent for much longer than spatial over-densities ...
Smith, Martin C.
core   +1 more source