Results 21 to 30 of about 752,871 (233)

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

The role of Blockchain technology in enhancing transparency and trust in green finance markets

Finance & Accounting Research Journal
This study explores the transformative potential of blockchain technology in green finance, aiming to assess how it enhances transparency, efficiency, and trust within the sector.
Ezekiel Onyekachukwu Udeh, Prisca Amajuoyi, Kudirat Bukola Adeusi, Anwulika Ogechukwu Scott   +3 more
semanticscholar   +1 more source

On the Influence of Minor Mergers on the Radial Abundance Gradient in Disks of Milky Way-like Galaxies

, 2015
We investigate the influence of stellar migration caused by minor mergers (mass ratio from 1:70 to 1:8) on the radial distribution of chemical abundances in the disks of Milky Way-like galaxies during the last four Gyr.
Berczik, Peter, Grebel, Eva K., Just, Andreas, Pilyugin, Leonid S., Zinchenko, Igor A.   +4 more
core   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

Stochastic heating of cooling flows

, 2009
It is generally accepted that the heating of gas in clusters of galaxies by active galactic nuclei (AGN) is a form of feedback. Feedback is required to ensure a long term, sustainable balance between heating and cooling. This work investigates the impact
Br��ggen, Dunn, Edward C. D. Pope, Fujita, Gardiner, Georgi Pavlovski, Goodman, Heinz, Litvinenko, McNamara, Peterson, Peterson, Pope, Rafferty, Ruszkowski, Scannapieco, Shahbaz, Tamura, Voigt   +18 more
core   +1 more source

The JCMT Transient Survey: An Extraordinary Submillimetre Flare in the T Tauri Binary System JW 566 [PDF]

, 2018
The binary T Tauri system JW 566 in the Orion Molecular Cloud underwent an energetic, short-lived flare observed at submillimetre wavelengths by the SCUBA-2 instrument on 26 November 2016 (UT).
Bell, Graham S., Bower, Geoffrey C., Chen, Wen-Ping, Forbrich, Jan, Hacar, Alvaro, Herczeg, Gregory J., Johnstone, Doug, Lalchand, Bhavana, Lee, Jeong-Eun, Mairs, Steve   +9 more
core   +4 more sources

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

CROSS-BORDER TAX CHALLENGES AND SOLUTIONS IN GLOBAL FINANCE

Finance & Accounting Research Journal
In the dynamic landscape of global finance, cross-border transactions have become increasingly prevalent, facilitating economic growth and international trade.
Joy Ojonoka Atadoga, Joseph Kuba Nembe, Noluthando Zamanjomane Mhlongo, Adeola Olusola Ajayi-Nifise, Odeyemi Olubusola, Andrew Ifesinachi Daraojimba, Bisola Beatrice Oguejiofor   +6 more
semanticscholar   +1 more source

Kinematically Detected Halo Streams

, 2016
Clues to the origins and evolution of our Galaxy can be found in the kinematics of stars around us. Remnants of accreted satellite galaxies produce over- densities in velocity-space, which can remain coherent for much longer than spatial over-densities ...
Smith, Martin C.
core   +1 more source

Repeat Expansions in PLIN4 Cause Autosomal Dominant Vacuolar Myopathy With Sarcolemmal Features

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to describe and characterize two unrelated Spanish families suffering from an autosomal dominant autophagic vacuolar myopathy caused by repeat expansions in PLIN4. Methods We evaluated the clinical phenotype and muscle imaging, and performed a genetic workup that included exome sequencing, muscle RNAseq, and long‐read genome ...
Laura Llansó, Igor Stevanovski, Germán Morís, Roger Collet‐Vidiella, Alba Segarra‐Casas, Lidia González‐Quereda, Benjamín Rodríguez‐Santiago, Pia Gallano, Rodrigo Alvarez, Ana Vesperinas, Rosa Blanco, Beatriz San‐Millán, Carmen Navarro, Isabel Illa, Gianina Ravenscroft, Ira W. Deveson, Eduard Gallardo, Montse Olivé   +17 more
wiley   +1 more source