Results 101 to 110 of about 280,695 (304)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Ace Alagna at Pieretti luncheon
, 2016 Ace Alagna was a photographer, editor and publisher of the Italian Tribune, and prominent member of the Italian American community in Newark, NJ. The Ace Alagna photographs consist of photographic negatives, prints, videos, and layout sheets from Ace ...
Alagna, 1925-2000, Ace (Armando)
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
, 2016 Ace Alagna was a photographer, editor and publisher of the Italian Tribune, and prominent member of the Italian American community in Newark, NJ. The Ace Alagna photographs consist of photographic negatives, prints, videos, and layout sheets from Ace ...
Alagna, 1925-2000, Ace (Armando)
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
, 2016 Ace Alagna was a photographer, editor and publisher of the Italian Tribune, and prominent member of the Italian American community in Newark, NJ. The Ace Alagna photographs consist of photographic negatives, prints, videos, and layout sheets from Ace ...
Alagna, 1925-2000, Ace (Armando)
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Leavin’ Trunk Blues / Ace Atkins. (2000)
, 2004 Ace Atkins. Leavin’ Trunk Blues. New York.
Atkins, Ace
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Ace Alagna in military uniform
, 2016 Ace Alagna was a photographer, editor and publisher of the Italian Tribune, and prominent member of the Italian American community in Newark, NJ. The Ace Alagna photographs consist of photographic negatives, prints, videos, and layout sheets from Ace ...
Alagna, 1925-2000, Ace (Armando)
core