Results 171 to 180 of about 928,751 (272)

Acceptance and Commitment to Empowerment Intervention to Reduce HIV Stigma and Promote Community Resilience: Protocol for an Implementation Study.

JMIR Res Protoc
Wong JP, Li AT, Hilario CT, Vahabi M, Etowa E, Luginaah I, Dela Cruz AM, Narushima M, Fung KP.   +8 more
europepmc   +1 more source

Identification of genetic markers associated with coronary artery disease in Pakistani Pashtun population: A case-control association study. [PDF]

Medicine (Baltimore)
Jan A, Ullah A, Khattak M, Shah WA, Akbar R, Nahla UA.   +5 more
europepmc   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Identification of ACE and HSPB8 as novel drug targets for LUSC treatment and prognosis based on a prognostic model integrating epigenetic regulation and endoplasmic reticulum stress-related genes. [PDF]

PLoS One
Zhou Y, Wang B, Song C, Xie W.
europepmc   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Pioneering adsorption-assisted electrochemical polymerization approach for the fabrication of an acetaminophen sensor: experimental and theoretical studies. [PDF]

RSC Adv
Elugoke SE, Feleni U, Adekunle AS, Nkambule TTI, Mamba BB, Ebenso EE.   +5 more
europepmc   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Objective prenatal sleep and adverse childhood experiences in a proof-of-concept observational mixed methods study. [PDF]

iScience
Rohr J, Lamichhane B, Sabharwal A, Bartek N, Bourassa K, Geng Y, Sano A, Madan A.   +7 more
europepmc   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Assessing the Accuracy of Global HFC-134a Satellite Observations from Atmospheric Chemistry Experiment Fourier Transform Spectrometer (ACE-FTS) via Aircraft, Balloon, and Model Comparisons. [PDF]

Environ Sci Technol
Li Y, Li J, Chen Y, Zhang L, Montzka SA, Vimont I, Crotwell M, Liu S, Li X, Fu W, Zhang P, Zhang X, Wu X, Zhang J, Huang Y, Luan X, Shen H, Ye J, Wang C, Yang X, Fu TM, Zhu L.   +21 more
europepmc   +1 more source