Results 41 to 50 of about 928,751 (272)

Multimodal nocturnal seizure detection: Do we need to adapt algorithms for children?

open access: yesEpilepsia Open, 2022
Objective To assess the performance of a multimodal seizure detection device, first tested in adults (sensitivity 86%, PPV 49%), in a pediatric cohort living at home or residential care.
Richard H.C. Lazeron   +10 more
doaj   +1 more source

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale   +6 more
wiley   +1 more source

Unveiling the sound of the cognitive status: Machine Learning-based speech analysis in the Alzheimer’s disease spectrum

open access: yesAlzheimer’s Research & Therapy
Background Advancement in screening tools accessible to the general population for the early detection of Alzheimer’s disease (AD) and prediction of its progression is essential for achieving timely therapeutic interventions and conducting decentralized ...
Fernando García-Gutiérrez   +20 more
doaj   +1 more source

Evaluation of the relationship between the minimum steady-state concentration of angiotensin II receptor blockers and polymorphic markers of CYP2C9 (Arg144Cys), CYP2C9 (IlE359Leu), AGTR1 (A1166C), AGT (Met235Thr, C4072T), ACE (I/D), CYP11B2 (C-344T) genes and office arterial pressure

open access: yesФармация и фармакология (Пятигорск)
The aim of the work was to study the relationship of the minimum steady-state concentration of angiotensin II receptor blockers with polymorphic markers of CYP2C9 (Arg144Cys), CYP2C9 (Ile359Leu), AGTR1 (A1166C), AGT (Met235Thr, C4072T), ACE (I/D ...
E. V. Rebrova   +5 more
doaj   +1 more source

Potential Early Risk Biomarkers for Reduced Forced Expiratory Volume in Children Post‐Hematopoietic Cell Transplantation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT We sought to identify potential early risk biomarkers for lung disease in children post‐allogeneic HCT. Patients with pulmonary function tests 3 months post‐transplant and plasma samples between days 7 and 14 post‐HCT were included. Six of 27 subjects enrolled had reduced forced expiratory volume 1 (FEV1) z scores.
Isabella S. Small   +3 more
wiley   +1 more source

Personalizing the Pediatric Hematology/Oncology Fellowship: Adapting Training for the Next Generation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT The pediatric hematology‐oncology fellowship training curriculum has not substantially changed since its inception. The first year of training is clinically focused, and the second and third years are devoted to scholarship. However, this current structure leaves many fellows less competitive in the current job market, resulting in ...
Scott C. Borinstein   +3 more
wiley   +1 more source

Changes in choroidal thickness quantified by Optical Coherence Tomography across cognitive impairment: data from the NORFACE cohort

open access: yesAlzheimer’s Research & Therapy
Background Optical coherence tomography (OCT) enables high-resolution imaging of ocular structures in health and disease. Choroid thickness (CT) is a key vascular retinal parameter that can be assessed by OCT and might be relevant in the evaluation of ...
Luis Castilla-Martí   +32 more
doaj   +1 more source

Phenotype and Genotype of Enterococcus faecalis Isolated form Root Canal and Saliva of Primary Endodontic Patients

open access: yesJournal of Dentistry Indonesia, 2016
This study was carried out to investigate the phenotype and genotype of E. faecalis isolated from the root canal and saliva of primary endodontic patients with periapical lesions.
Zaki Mubarak   +3 more
doaj   +1 more source

Timing of the solar wind propagation delay between L1 and Earth based on machine learning

open access: yesJournal of Space Weather and Space Climate, 2021
Erroneous GNSS positioning, failures in spacecraft operations and power outages due to geomagnetically induced currents are severe threats originating from space weather. Knowing the potential impacts on modern society in advance is key for many end-user
Baumann Carsten, McCloskey Aoife E.
doaj   +1 more source

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