Results 41 to 50 of about 930,951 (296)

Real‐World Pediatric Blinatumomab Administration: Access to Outpatient Care Delivery and Impact of a Hospital‐Dispensed Model

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab has been shown to be highly effective for patients with pediatric B‐ALL and has recently become standard of care therapy. Due to its past use in the clinical trial setting, there is limited information available about real‐world administration.
Katelyn Oranges, Kelly A. Duffy, Sara McDonough, Evelyn Kurpiewski, R. Jennifer Randall, Allison Barz Leahy, Haley M. Newman, Joyce P. Lee, Stephen P. Hunger, Anne F. Reilly, David T. Teachey, Susan R. Rheingold, Daniel J. Zheng   +12 more
wiley   +1 more source

Evaluation of the relationship between the minimum steady-state concentration of angiotensin II receptor blockers and polymorphic markers of CYP2C9 (Arg144Cys), CYP2C9 (IlE359Leu), AGTR1 (A1166C), AGT (Met235Thr, C4072T), ACE (I/D), CYP11B2 (C-344T) genes and office arterial pressure

Фармация и фармакология (Пятигорск)
The aim of the work was to study the relationship of the minimum steady-state concentration of angiotensin II receptor blockers with polymorphic markers of CYP2C9 (Arg144Cys), CYP2C9 (Ile359Leu), AGTR1 (A1166C), AGT (Met235Thr, C4072T), ACE (I/D ...
E. V. Rebrova, E. V. Shikh, V. V. Smirnov, G. S. Anikin, L. M. Ignatova, M. M. Bogdanov   +5 more
doaj   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Is there a difference between an angiotensin-converting enzyme inhibitor and an angiotensin-specific receptor blocker for the treatment of hypertension?

South African Family Practice, 2015
No abstract available.
James A. Ker
doaj   +1 more source

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source

Changes in choroidal thickness quantified by Optical Coherence Tomography across cognitive impairment: data from the NORFACE cohort

Alzheimer’s Research & Therapy
Background Optical coherence tomography (OCT) enables high-resolution imaging of ocular structures in health and disease. Choroid thickness (CT) is a key vascular retinal parameter that can be assessed by OCT and might be relevant in the evaluation of ...
Luis Castilla-Martí, Ainhoa García-Sánchez, Joan Martínez, Maitée Rosende-Roca, Liliana Vargas, Juan Pablo Tartari, Federico Casales, José Nelet Rodríguez, Natali Bein, Montserrat Alegret, Gemma Ortega, Ana Espinosa, Ángela Sanabria, Alba Pérez-Cordón, Nathalia Muñoz, Fernando García-Gutiérrez, Josep Blazquez-Folch, Andrea Miguel, Itziar de Rojas, Pablo García-González, Raquel Puerta, Clàudia Olivé, Maria Capdevila, Álvaro Muñoz-Morales, Paula Bayón-Buján, Amanda Cano, Victoria Fernández, Sergi Valero, Lluís Tárraga, Agustín Ruiz, Mercè Boada, Miguel Castilla-Martí, Marta Marquié   +32 more
doaj   +1 more source

Phenotype and Genotype of Enterococcus faecalis Isolated form Root Canal and Saliva of Primary Endodontic Patients

Journal of Dentistry Indonesia, 2016
This study was carried out to investigate the phenotype and genotype of E. faecalis isolated from the root canal and saliva of primary endodontic patients with periapical lesions.
Zaki Mubarak, Widya Asmara, Tri Wibawa, Boy M. Bachtiar   +3 more
doaj   +1 more source

Timing of the solar wind propagation delay between L1 and Earth based on machine learning

Journal of Space Weather and Space Climate, 2021
Erroneous GNSS positioning, failures in spacecraft operations and power outages due to geomagnetically induced currents are severe threats originating from space weather. Knowing the potential impacts on modern society in advance is key for many end-user
Baumann Carsten, McCloskey Aoife E.
doaj   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Anomalous cosmic ray composition from ACE [PDF]

, 2000
During solar quiet periods, the Solar Isotope Spectrometer (SIS) on the Advanced Composition Explorer (ACE) measures the composition and energy spectra of anomalous cosmic rays (ACRs) with energies >8 MeV/nucleon in interplanetary space at 1 AU.
Leske, R. A.
core   +1 more source