Results 261 to 270 of about 132,338 (329)
COVID‐19 and Pregnancy: Key Findings
Mechanistic overview of maternal SARS‐CoV‐2 immunisation, affinity‐matured IgG production, FcRn‐mediated transplacental IgG transport, and antibody delivery to the newborn via fetal circulation and breast milk. The schematic also highlights the translational relevance of murine models, which share conserved mechanisms of antibody induction despite ...
Gabrielle Gimenes Lima +5 more
wiley +1 more source
Broad-spectrum inhibition of SARS-CoV-2 variants by dibutyl phthalate through allosteric disruption of Spike-ACE2 interface. [PDF]
Chen J +8 more
europepmc +1 more source
Abstract Ageing negatively affects quality of life and healthspan, and interventions are needed to slow this progressive decline. Previously, we have demonstrated the potential functional benefits of combining a genetically modified probiotic (GMP) targeting the non‐canonical arm of the renin–angiotensin system (RAS) with exercise training.
Emily L. Zumbro +8 more
wiley +1 more source
Disruption of spike protein N-glycosylation induces its endoplasmic reticulum retention and attenuates SARS-CoV-2 infectivity. [PDF]
Kong W +8 more
europepmc +1 more source
Abstract Menopause increases the risk of hypertension in women, yet the factors contributing to this important change remain unclear. Because early life stress has persistent and sex‐specific consequences on health, we hypothesized that ageing reveals the latent effects of neonatal maternal separation (NMS) on cardiovascular homeostasis in female rats.
Danuzia Ambrozio‐Marques +6 more
wiley +1 more source
<i>Eupatorium lindleyanum</i> DC. Suppresses Cytokine Storm by Inhibiting NF-κB and PI3K-Akt Signaling in Sepsis-Associated and Virus-Related Acute Lung Injury. [PDF]
Luo C +10 more
europepmc +1 more source
Hypertension drives cognitive decline through a previously unrecognized CCN1–integrin αvβ6–TGF‐β signaling axis that culminates in mitochondrial dysfunction and hippocampal neuronal injury. In this pathway, angiotensin II induces CCN1 upregulation, which activates αvβ6 integrin‐mediated release of latent TGF‐β, triggering SMAD2/3 phosphorylation and ...
Xufang Huo +10 more
wiley +1 more source
SARS-CoV-2 pseudoparticles preferentially infect ectoderm in human embryonic tissues. [PDF]
Song A, Talbot P.
europepmc +1 more source

