Results 181 to 190 of about 89,590 (297)

Safety and tolerability of the ACE-inhibitor lisinopril among Nigerian adults with HIV: preliminary pilot data from a randomized clinical trial. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Dankishiya FS, Muhammad H, Wudil UJ, Musa BM, Du L, Adam IA, Ahonkhai AA, Burgner AM, Nalado AM, Sani MU, Abdu A, Shepherd BE, Aliyu MH, Wester CW.   +13 more
europepmc   +1 more source

Sustainable Production of Biosurfactant from Agro-Industrial Oil Wastes by Bacillus subtilis and Its Potential Application as Antioxidant and ACE Inhibitor. [PDF]

Int J Mol Sci, 2022
Ciurko D, Czyżnikowska Ż, Kancelista A, Łaba W, Janek T.   +4 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Efficacy of Icatibant as Treatment for ACE Inhibitor-Induced Angioedema in Adults: A Systematic Review

, 2011
Background: ACE inhibitor-induced angioedema is a rare, yet potentially fatal, drug side effect. Considering nearly 40 million people are taking ACE inhibitors for their anti-hypertensive and renal-protective benefits, a significant number of patients ...
Burr, Jessie A
core  

ACE inhibitor-induced bradykinin-mediated angioedema presenting as small bowel obstruction and life-threatening airway angioedema: a rare dual presentation. [PDF]

BMJ Case Rep
Ghimire P, Sathya DA, Tang A, Yaqoob H.
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Angiotensin-Converting Enzyme (ACE) Inhibitor-Induced Angioedema Presenting After Long-Term Antihypertensive Therapy: A Case Report. [PDF]

Cureus
Khalid M, Nafis S.
europepmc   +1 more source

Mortality and Morbidity Among Individuals With Hypertension Receiving a Diuretic, ACE Inhibitor, or Calcium Channel Blocker: A Secondary Analysis of a Randomized Clinical Trial.

JAMA Netw Open, 2023
Yamal JM, Martinez J, Osani MC, Du XL, Simpson LM, Davis BR.   +5 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Mining and engineering of ene-reductases from marine sediment metagenome for prochiral ACE inhibitor synthesis. [PDF]

Appl Environ Microbiol
Zou Y, Zhou J, Zeng Y, Chen B, Liu L, Xu G.   +5 more
europepmc   +1 more source