Results 21 to 30 of about 81,765 (240)

Prodrug ACE Inhibitors [PDF]

open access: yesCirculation, 1998
To the Editor: In a recent issue of Circulation , Brown and Vaughan1 reviewed ACE inhibitors. They stated that captopril and lisinopril are active drugs and listed 7 other ACE inhibitors approved in the United States that are inactive prodrugs until metabolized in the liver.
openaire   +2 more sources

THE USE OF ANGIOTENSIN CONVERTING ENZYME INHIBITORS AFTER MYOCARDIAL INFARCTION. WHAT DO EVIDENCE-BASED MEDICINE DATA SPEAK FOR?

open access: yesРациональная фармакотерапия в кардиологии, 2016
The main trails proven angiotensin converting enzyme (ACE) inhibitor effects on the life prognosis after myocardial infarction (MI) are described. Different tactics of ACE inhibitors therapy in post MI patients are presented.
S. Yu. Martsevich
doaj   +1 more source

ACE as a mechanosensor to shear stress influences the control of its own regulation via phosphorylation of cytoplasmic Ser(1270). [PDF]

open access: yesPLoS ONE, 2011
OBJECTIVES: We tested whether angiotensin converting enzyme (ACE) and phosphorylation of Ser(1270) are involved in shear-stress (SS)-induced downregulation of the enzyme.
Valerio Garrone Barauna   +3 more
doaj   +1 more source

Captopril-Associated Cough Is Not due to Increased Airway Responsiveness

open access: yesCanadian Respiratory Journal, 1994
BACKGROUND: Angiotensin-converting enzyme (ACE) inhibitors commonly cause cough. There is controversy as to whether preexisting airway hyperresponsivencss predisposes patients to ACE inhibitor-induced cough and whether ACE inhibitor therapy can cause ...
SP Blackie   +4 more
doaj   +1 more source

Cardiovascular and Renal Outcomes of Renin-Angiotensin System Blockade in Adult Patients with Diabetes Mellitus: A Systematic Review with Network Meta-Analyses.

open access: yesPLoS Medicine, 2016
BackgroundMedications aimed at inhibiting the renin-angiotensin system (RAS) have been used extensively for preventing cardiovascular and renal complications in patients with diabetes, but data that compare their clinical effectiveness are limited.
Ferrán Catalá-López   +11 more
doaj   +1 more source

Effect of angiotensin converting enzyme inhibitor and angiotensin II receptor blocker on the patients with sepsis [PDF]

open access: yesThe Korean Journal of Internal Medicine, 2021
Background/Aims Inhibitors of the renin-angiotensin system, angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs), reportedly have anti-inflammatory effects.
Hyun Woo Lee   +3 more
doaj   +1 more source

To Treat or Not to Treat? Cost-Effectiveness of Ace Inhibitors in Non-Diabetic Advanced Renal Disease - a Dutch Perspective

open access: yesKidney & Blood Pressure Research, 2013
Background: Treating non-diabetic proteinuric patients with advanced renal disease with an angiotensin-converting enzyme (ACE) inhibitor is still subject to discussion.
Charles Christian Adarkwah   +3 more
doaj   +1 more source

Dose response of ACE inhibitors: implications of the SECURE trial

open access: yesCurrent Controlled Trials in Cardiovascular Medicine, 2001
The choice of the appropriate dosage of ACE inhibitor in clinical practice is an important one. The available evidence suggests that in chronic heart failure as well as in chronic coronary artery disease, high doses of angiotensin-converting enzyme (ACE)
Lonn Eva
doaj   +1 more source

Effect of angiotensin‐converting enzyme inhibition on cardiovascular adaptation to exercise training

open access: yesPhysiological Reports, 2022
Angiotensin‐converting enzyme (ACE) activity may be one determinant of adaptability to exercise training, but well‐controlled studies in humans without confounding conditions are lacking.
Tórur Sjúrðarson   +13 more
doaj   +1 more source

Therapeutic approaches to slowing the progression of diabetic nephropathy – is less best?

open access: yesDrugs in Context, 2013
Objective: Angiotensin II receptor blockers (ARBs) and angiotensin-converting enzyme (ACE) inhibitors are known to reduce proteinuria and have been the first-line agents in the management of diabetic nephropathy for the past 20 years.
Eva Vivian, Chelsea Mannebach
doaj   +1 more source

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