BNP secreted by left ventricle as response to wall stress in patient with heart failure. Elevated concentration of NT-pro-BNP correlate with severity of heart failure across all stages of the condition and left ventricle ejection fraction in patient ...
Halla Hisan Hartoto +2 more
doaj +1 more source
Hubungan Pengetahuan Pasien Hipertensi Tentang Obat Golongan Ace Inhibitor Dengan Kepatuhan Pasien Dalam Pelaksanaan Terapi Hipertensi Di Rsup Prof Dr. R. D. Kandou Manado [PDF]
The success of treatment of hypertension requires adherence to dietary instructions and therecommended drugs. Education about hypertension and the importance of adherence and sideeffects of drugs administered to the patient is necessary.
Sarampang, Y. T. (Yosprinto)
core +3 more sources
Therapeutic approaches to slowing the progression of diabetic nephropathy – is less best?
Objective: Angiotensin II receptor blockers (ARBs) and angiotensin-converting enzyme (ACE) inhibitors are known to reduce proteinuria and have been the first-line agents in the management of diabetic nephropathy for the past 20 years.
Eva Vivian, Chelsea Mannebach
doaj +1 more source
Activation of Rac-1 and RhoA contributes to podocyte injury in chronic kidney disease [PDF]
Rho-family GTPases like RhoA and Rac-1 are potent regulators of cellular signaling that control gene expression, migration and inflammation. Activation of Rho-GTPases has been linked to podocyte dysfunction, a feature of chronic kidney diseases (CKD). We
Amann, Kerstin +13 more
core +4 more sources
About 8% of the adult population is taking angiotensin-converting enzyme (ACE) inhibitors to treat cardiovascular disease including hypertension, myocardial infarction and heart failure. These drugs decrease mortality by up to one-fifth in these patients.
Miklós Fagyas +13 more
doaj +1 more source
Individualized Angiotensin‐Converting Enzyme (ACE)‐Inhibitor Therapy in Stable Coronary Artery Disease Based on Clinical and Pharmacogenetic Determinants: The PERindopril GENEtic (PERGENE) Risk Model [PDF]
Patients with stable coronary artery disease (CAD) constitute a heterogeneous group in which the treatment benefits by angiotensin-converting enzyme (ACE)-inhibitor therapy vary between individuals.
Akkerhuis, KM +14 more
core +1 more source
ACE, ACE Inhibitors, and Other JNK [PDF]
The renin-angiotensin system (RAS) plays a pivotal role in the regulation of blood pressure, volume homeostasis, vascular function, and cell growth. In what is considered the classic RAS, renin is released from juxtaglomerular cells of the kidney into the circulation where it converts angiotensinogen from the liver to angiotensin I.
Curt D. Sigmund, Michael J. Ryan
openaire +2 more sources
Background: Angiotensin converting enzyme (ACE) inhibitor and angiotensin receptor blocker (ARB) may induce acute kidney injury (AKI). The aim of this study was to evaluate the role of the resistive index (RI), which reflects renal artery resistance on ...
Eun Seok Kim +9 more
doaj +1 more source
Gambaran Peresepan Ace Inhibitor Pada Pasien Gagal Jantung Yang Dirawat Inap Di Rsup Dr Kariadi Semarang Periode Januari – Desember 2013 [PDF]
Background : Heart failure is a clinical syndrome caused by abnormalities of cardiac structure or function. The prevalence of heart failure is increasing and caused loss of quality of life.
Arianda, R. H. (R) +2 more
core
Pharmacist intervention in primary care to improve outcomes in patients with left ventricular systolic dysfunction [PDF]
<b>Background</b> Meta-analysis of small trials suggests that pharmacist-led collaborative review and revision of medical treatment may improve outcomes in heart failure.<p></p> <b>Methods and results</b> We studied
Forsyth, P. +7 more
core +1 more source

