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Anxiolytic effects of ACE inhibitory peptides on the behavior of rats in an elevated plus-maze
Food & Function, 2016Three novel egg white-derived peptides were demonstrated to display in vitro activities against the angiotensin converting enzyme (ACE).
Zhipeng, Yu +4 more
openaire +2 more sources
Food Chemistry
Hypertension remains a major global health challenge and is associated with increased cardiovascular risk. Angiotensin-converting enzyme (ACE) plays a pivotal role in blood pressure regulation; however, conventional synthetic ACE inhibitors are often accompanied by undesirable side effects.
Siyuan, Peng +5 more
openaire +2 more sources
Hypertension remains a major global health challenge and is associated with increased cardiovascular risk. Angiotensin-converting enzyme (ACE) plays a pivotal role in blood pressure regulation; however, conventional synthetic ACE inhibitors are often accompanied by undesirable side effects.
Siyuan, Peng +5 more
openaire +2 more sources
Methods
Identifying angiotensin-I-converting enzyme (ACE) inhibitory peptides accurately is crucial for understanding the primary factor that regulates the renin-angiotensin system and for providing guidance in developing new potential drugs. Given the inherent experimental complexities, using computational methods for in silico peptide identification could be
Phasit, Charoenkwan +3 more
openaire +2 more sources
Identifying angiotensin-I-converting enzyme (ACE) inhibitory peptides accurately is crucial for understanding the primary factor that regulates the renin-angiotensin system and for providing guidance in developing new potential drugs. Given the inherent experimental complexities, using computational methods for in silico peptide identification could be
Phasit, Charoenkwan +3 more
openaire +2 more sources
Predicting variable-length ACE inhibitory peptides based on graph convolutional network
International Journal of Biological MacromoleculesTraditional molecular descriptors have contributed to the prediction of angiotensin I-converting enzyme (ACE) inhibitory peptides, but they often fall short in capturing the complex structure of the molecule. To address these limitations, this study introduces molecular graphs as an advanced method for peptide characterization. Peptides containing 2-10
Yating, Rong +12 more
openaire +2 more sources
Transport and action of sesame protein-derived ACE inhibitory peptides ITAPHW and IRPNGL
Food ChemistryVascular endothelial dysfunction is an important pathogenic factor in hypertension, in which angiotensin-converting enzyme (ACE) plays an important role. Peptides that bind to ACE may attenuate vascular endothelial dysfunction by altering the structure of ACE.
Tonghao, Du +12 more
openaire +2 more sources
Identification and molecular interactions of novel ACE inhibitory peptides from rapeseed protein
Food Chemistry, 2023Guanhao Bu +2 more
exaly
Characterization of ACE Inhibitory Peptides Prepared from Pyropia pseudolinearis Protein
Marine Drugs, 2021Hideki Kishimura +2 more
exaly

