Me-too pharmaceutical products: History, definitions, examples, and relevance to drug shortages and essential medicines lists. [PDF]
Br J Clin Pharmacol, 2020 We define a me‐too drug as a pharmacologically active compound that is structurally related to a first‐in‐class compound, regarded as belonging to the same therapeutic class as the original compound, and used for the same therapeutic purposes, but which may differ in some respects, such as specificity of pharmacological action, adverse reactions ...
Aronson JK, Green AR.
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Molecular basis of the different effects of procainamide and N-acetylprocainamide on the maximum upstroke velocity and half-decay time of the cardiac action potential in guinea pig papillary muscle. [PDF]
Braz J Med Biol Res, 2023 Sigler W, Oliveira AC.
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General access to cubanes as benzene bioisosteres. [PDF]
Nature, 2023 Wiesenfeldt MP +10 more
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Chemical Tagging of Bioactive Amides by Cooperative Catalysis: Applications in the Syntheses of Drug Conjugates. [PDF]
J Am Chem Soc, 2023 Zhao C +5 more
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Evaluation of Antibacterial Activity of Aqueous, Ethanolic and Methanolic Extracts of Areca Nut Fruit on Selected Bacteria. [PDF]
Biomed Res Int, 2021 Jam N +3 more
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Examination of Urinary Excretion of Unchanged Drug in Humans and Preclinical Animal Models: Increasing the Predictability of Poor Metabolism in Humans. [PDF]
Pharm Res, 2021 Bamfo NO +3 more
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Revisiting the application of Immobilized Artificial Membrane (IAM) chromatography to estimate in vivo distribution properties of drug discovery compounds based on the model of marketed drugs. [PDF]
ADMET DMPK, 2020 Valko K, Rava S, Bunally S, Anderson S.
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Pharmacokinetic modeling and simulation of procainamide and N-acetylprocainamide in a patient receiving continuous renal replacement therapy: a novel approach to guide renal dose adjustments. [PDF]
Am J Kidney Dis, 2013 Mohamed AN +5 more
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Levofloxacin and ciprofloxacin decrease procainamide and N-acetylprocainamide renal clearances. [PDF]
Antimicrob Agents Chemother, 2005 Bauer LA +5 more
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Overview of therapeutic drug monitoring. [PDF]
Korean J Intern Med, 2009 Kang JS, Lee MH.
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