Results 1 to 10 of about 7,102 (207)
Annals of Noninvasive Electrocardiology, Volume 31, Issue 5, September 2026.In NHANES III adults, latent class trajectory analysis identified a J‐point phenotype characterized by higher V4 amplitude and a steep decline toward V6. This spatial trajectory was independently associated with increased long‐term all‐cause mortality and cardiac death, suggesting prognostic value beyond conventional early repolarization criteria ...
Chenhui Tai, Zhe Wang
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The Analysis of Human Serum N-Glycosylation in Patients with Primary and Metastatic Brain Tumors
Life, 2021 The identification of patients with different brain tumors is solely built on imaging diagnostics, indicating the need for novel methods to facilitate disease recognition.
Csaba Váradi +5 more
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Journal of Cardiovascular Electrophysiology, Volume 37, Issue 9, Page 1939-1946, September 2026.ABSTRACT Introduction Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a potentially life‐threatening arrhythmic disorder typically treated with beta‐blockers and, occasionally, with flecainide. Methods All patients underwent genetic testing, electrocardiogram, echocardiogram, and exercise testing.
Fernando Wangüemert‐Perez +9 more
wiley +1 more source
Autoimmune Disease Risk With GLP‐1RA, DPP‐4i, and SGLT2i Treatment in Patients With Diabetes
ACR Open Rheumatology, Volume 8, Issue 7, July 2026.Objective Dipeptidyl peptidase‐4 inhibitors (DPP‐4i), glucagon‐like peptide‐1 receptor agonists (GLP‐1RA), and sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) are widely used for type 2 diabetes, yet their comparative immunologic safety is uncertain.
Arjun Mahajan +5 more
wiley +1 more source
Molecular modeling studies of the novel inhibitors of DNA methyltransferases SGI-1027 and CBC12: implications for the mechanism of inhibition of DNMTs. [PDF]
PLoS ONE, 2013 DNA methylation is an epigenetic modification that regulates gene expression by DNA methyltransferases (DNMTs). Inhibition of DNMTs is a promising approach for cancer therapy.
Jakyung Yoo +2 more
doaj +1 more source
Drug Critical Limits for Urgent Physician Notification
Clinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 178-192, July 2026.Critical limits represent quantitative decision thresholds for drugs that require immediate clinician notification and potential life‐saving intervention. United States hospitals lack a national standard for drug critical limits. We collected critical limits from 417 US hospitals across all 50 states and Washington, D.C.; of these, 411 maintained drug ...
Elina Kuang +3 more
wiley +1 more source
Cardiac remodeling and arrhythmia in a mouse model of Depdc5 haploinsufficiency
Epilepsia, Volume 67, Issue 7, Page 3738-3752, July 2026.Abstract Objective Some ion channel genes linked to developmental and epileptic encephalopathy (DEE) are also linked to cardiac arrhythmia, leading to the hypothesis that predisposition to cardiac arrhythmias may contribute to the complex disease presentation of DEE and possibly to the mechanism of sudden unexpected death in epilepsy.
Roberto Ramos‐Mondragon +9 more
wiley +1 more source
The Journal of Physiology, Volume 604, Issue 13, Page 5629-5662, 1 July 2026.Abstract figure legend A study described in this paper describes a new tool for hiPSC‐CM electromechanical behaviour simulations using mathematical modelling. The model enables in silico assays making drug testing quick, comprehensive and accurate. New hiPSC‐CM models can be used as a platform to integrate in vitro and in silico findings.
Milda Folkmanaite +9 more
wiley +1 more source
A review on dronedarone: Pharmacological, pharmacodynamic and pharmacokinetic profile
Journal of Acute Disease, 2016 Dronedarone, a benzofuran containing chemical compound, is a derivative of amiodarone which is classified as a Class III antiarrhythmic agent. It is prescribed to the cardiovascular patients who have paroxysmal or persistent atrial fibrillation to lower ...
Farah Iram +4 more
doaj +1 more source
American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1326-1336, June 2026.ABSTRACT Substantial data supports the use of rapid exome and genome sequencing (rES/rGS) in Neonatal Intensive Care Units (NICU), but fewer studies have examined the impact of rES/rGS in other pediatric critical care units. We evaluated the impact on diagnostic yield and time to diagnosis following a single‐center hospital policy change allowing ...
Alexandra C. Keefe +22 more
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