Results 21 to 30 of about 7,102 (207)
Identification of novel DNA methylation inhibitors via a two-component reporter gene system
Journal of Biomedical Science, 2011 Background Targeting abnormal DNA methylation represents a therapeutically relevant strategy for cancer treatment as demonstrated by the US Food and Drug Administration approval of the DNA methyltransferase inhibitors azacytidine and 5-aza-2 ...
Chen Ching-Shih +9 more
doaj +1 more source
Isotretinoin induced myopericarditis – A case report and literature review
IHJ Cardiovascular Case Reports, 2022 Drug induced pericarditis is a well described entity, most commonly described secondary to hydralazine, procainamide and isoniazid. Cardiac involvement after systemic retinoic acid therapy is exceedingly rare.
Abraham Paul, Balakrishnan N
doaj +1 more source
Alexandria Journal of Medicine, 2015 Background: Diabetes mellitus (DM) is a metabolic disease that is associated with disturbed carbohydrates, lipids and protein metabolism due to insulin deficiency and/or impaired insulin action. Recently epigenetic mechanisms were shown to be involved in
Wessam F. El-Hadidy +2 more
doaj +1 more source
The Clinical Utility of Procainamide-induced Late Potentials on the Signal Averaged ECG [PDF]
, 2021 Background: Late potentials (LPs) identified on the signal averaged electrocardiogram (SAECG) are a marker for an increased risk of arrhythmias in Brugada syndrome (BrS). Procainamide is a sodium channel blocker used to diagnose BrS.
Walia, Jagdeep +15 more
core +1 more source
Pharmacodynamics of intravenous procainamide as used during acute electropharmacologic testing [PDF]
, 1988 No previous studies have determined the pharmacodynamics of intravenous procainamide when administered in a dose of 15 mg/kg and at a rate of 50 mg/min, as is common practice during etectropharmacologic testing.
Nelson, Steven D. +6 more
core +1 more source
Frontiers in Chemistry, 2018 Rising awareness of the universal importance of protein N-glycosylation governs the development of further advances in N-glycan analysis. Nowadays it is well known that correct glycosylation is essential for proper protein function, which emanates from ...
Toma Keser +4 more
doaj +1 more source
Effect of procainamide on myocardial contractile function and digoxin inotropy [PDF]
, 1984 The effect of procainamide and digoxin, singly and together, on peak active force and rate of force development of isolated right ventricular papillary muscles from adult cats was examined.
John F. Williams +3 more
core +1 more source
Kaohsiung Journal of Medical Sciences, 2007 Atrial electrical remodeling (ER) after spontaneous or pacing-induced atrial fibrillation has been previously described in humans. We investigated atrial ER induced by a 5-minute period of rapid atrial pacing and the pharmacologic effects of verapamil ...
Chih-Sheng Chu +7 more
doaj +1 more source
Pharmaceutics, 2018 A simple, sensitive, and reliable reversed-phase, Ultra-High-Pressure Liquid Chromatography (UHPLC) coupled with a Diode Array Detector (DAD) method for the simultaneous determination of Procainamide (PA) and its major metabolite, N-acetylprocainamide ...
Anusha Balla +3 more
doaj +1 more source
Reduced acetylation of procainamide by para-aminobenzoic acid [PDF]
, 1986 Acetylation is the major route of metabolism of many drugs including the antiarrhythmic agent procainamide. Coadministration of para-aminobenzoic acid was observed to decrease the biotransformation of procainamide to N-acetylprocainamide in a patient ...
Cohen, Andrew I. +4 more
core +1 more source