Results 31 to 40 of about 7,102 (207)

Physiologically-Based Pharmacokinetic Modeling for Drug-Drug Interactions of Procainamide and N-Acetylprocainamide with Cimetidine, an Inhibitor of rOCT2 and rMATE1, in Rats

open access: yesPharmaceutics, 2019
Previous observations demonstrated that cimetidine decreased the clearance of procainamide (PA) and/or N-acetylprocainamide (NAPA; the primary metabolite of PA) resulting in the increased systemic exposure and the decrease of urinary excretion.
Yoo-Seong Jeong   +4 more
doaj   +1 more source

EFFECT OF STORAGE ON THE IN-VITRO AND IN-VIVO CHARACTERISTICS OF SOME MARKETED SUSTAINED-RELEASE CARDIOVASCULAR TABLETS [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 1998
The in-vitro and in-vivo characteristics of the sustained-release cardiovascular drugs: nifedipine (N) nad procainamide (PA), commercially available as Adalat-Retard and Procainamide durules tablets were evaluated both before and after their storage at ...
Yousry El-Sayed   +2 more
doaj   +1 more source

Comparative electrophysiologic effects of intravenous and oral procainamide in patients with sustained ventricular arrhythmias [PDF]

open access: yes, 1984
Thirty-three patients with sustained ventricular arrhythmias underwent electrophysiologic testing after intravenous and again after oral procainamide administration.
Buxton, Alfred E.   +13 more
core   +1 more source

Unmasked by Fever: Diagnosing Brugada Syndrome After Ventricular Fibrillation Arrest

open access: yesAnnals of Internal Medicine: Clinical Cases, 2023
A 65-year-old man presented to the emergency department after he was resuscitated from cardiac arrest due to ventricular fibrillation. Coronary angiography demonstrated no evidence of coronary artery disease. Follow-up electrocardiograms (ECGs) were also
Theodore Peng   +3 more
doaj   +1 more source

Cyclodextrin potentiometric sensors based on selective recognition sites for procainamide: Comparative and theoretical study

open access: yesOpen Chemistry, 2019
Polyvinyl chloride (PVC) membrane sensors were constructed and developed for the determination of procainamide HCl (PR). Three membrane sensors incorporating α-, β- and γ- cyclodextrin (CD) as ionophores with potassium tetrakis (4-chlorophenyl) borate ...
AlRabiah Haitham   +3 more
doaj   +1 more source

Design of Intelligent Molecules as Models for Production of New Anti-alzheimer´s Medicines Using Epigenetic Modulation

open access: yesChemical Engineering Transactions, 2019
Alzheimer's disease is a neurodegenerative illness, so far without cure, that affects an increasing number of people around the world. Due to the adverse effects caused by drugs for treating this disease currently in clinical use, it is necessary to ...
Geane Oliveira   +4 more
doaj   +1 more source

Periodic procainamide for paroxysmal tachycardia.

open access: yes, 1985
We evaluated the efficacy of a single oral dose of procainamide to terminate paroxysmal tachycardia, when procainamide was taken shortly after onset of tachycardia, a regimen we have termed "periodic procainamide." In 12 patients (mean age 15 years) with
T P Green   +4 more
core   +1 more source

Diagnosis and management of junctional ectopic tachycardia in children

open access: yesAnnals of Pediatric Cardiology, 2021
Junctional ectopic tachycardia (JET) is more common in its postoperative form. A thorough understanding of its etiology, pathophysiology, and management strategies is essential.
Navaneetha Sasikumar   +2 more
doaj   +1 more source

Effects of procainamide on mean arterial pressure in endotoxemic rats.

open access: yes, 2016
Depicted are the changes during the experimental period in different groups of animals that received saline at time 0 (Control, n = 8), received saline as in Control group and then received procainamide at 1 h (Control + Procainamide, n = 8), received ...
Yung-Lung Chang (833564)   +8 more
core   +1 more source

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