Arrhythmogenic drugs can amplify spatial heterogeneities in the electrical restitution in perfused guinea-pig heart: An evidence from assessments of monophasic action potential durations and JT intervals. [PDF]
PLoS ONE, 2018 Non-uniform shortening of the action potential duration (APD90) in different myocardial regions upon heart rate acceleration can set abnormal repolarization gradients and promote arrhythmia.
Oleg E Osadchii
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Drug metabolism by flavin-containing monooxygenases of human and mouse [PDF]
, 2016 Introduction: Flavin-containing monooxygenases (FMOs) play an important role in drug metabolism. / Areas covered: We focus on the role of FMOs in the metabolism of drugs in human and mouse.
Phillips, IR, Shephard, EA
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Procainamide, oxprenolol and amiodarone as antidysrhythmic drugs in myocardial infarction.
Acta Médica Portuguesa, 1980 Using Holter recordings and based on the principle that most of the survivors of acute myocardial infarction who are going to die suddenly after hospital discharge are those who present ventricular premature beats (VPB), the authors have studied the ...
J. L. Tuna +5 more
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Epigenetically Altered T Cells Contribute to Lupus Flares
Cells, 2019 Lupus flares when genetically predisposed people encounter exogenous agents such as infections and sun exposure and drugs such as procainamide and hydralazine, but the mechanisms by which these agents trigger the flares has been unclear. Current evidence
Bruce Richardson
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Effect of voltage-gated sodium channels blockers on motility and viability of human sperm in vitro
Asian Pacific Journal of Reproduction, 2018 Objective: To test the effect of voltage-gated sodium channels (VGSCs) blockers on the motility and viability of human sperm in-vitro and to evaluate the tested compounds as potential contact spermicidal.Methods: Sperm samples were obtained from healthy ...
Hammad Ahmad Gakhar +3 more
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Characteristics and identification of sites of chagasic ventricular tachycardia by endocardial mapping [PDF]
, 1999 OBJECTIVE: To study electrophysiological characteristics that enable the identification and ablation of sites of chagasic tachycardia. METHODS: Thirty-one patients with chronic Chagas' heart disease and sustained ventricular tachycardia (SVT) underwent ...
De Paola, Angelo Amato Vincenzo +5 more
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Angewandte Chemie International Edition, EarlyView.This review highlights recent advances in integrating biocatalysis and chemocatalysis in continuous flow to create streamlined, sustainable processes. It examines chemo‐enzymatic cascades combining at least one enzymatic and one chemical step, discusses challenges such as enzyme immobilization, leaching, and reactor clogging, and presents solutions ...
Petros Siasiaridis +2 more
wiley +1 more source
Aromatic Amines Exert Contrasting Effects on the Anticoagulant Effect of Acetaldehyde upon APTT
Advances in Hematology, 2014 The pharmacological effects of amphetamine, procaine, procainamide, DOPA, isoproterenol, and atenolol upon activated partial thromboplastin time in the absence and presence of acetaldehyde have been investigated.
La'Teese Hall +2 more
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Wolff-Parkinson-White Syndrome: Electrocardiogram
Journal of Education and Teaching in Emergency Medicine, 2016 History of present illness: A 26-year-old male with no significant past medical history presented to the emergency department with palpitations. The patient experienced these symptoms five times before in his life, but they had self-resolved with ...
Brianna Miner +2 more
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