Results 11 to 20 of about 38 (37)

Predicting Dyspnea Inducers by Molecular Topology

Journal of Chemistry, Volume 2013, Issue 1, 2013., 2013
QSAR based on molecular topology (MT) is an excellent methodology used in predicting physicochemical and biological properties of compounds. This approach is applied here for the development of a mathematical model capable to recognize drugs showing dyspnea as a side effect.
María Gálvez-Llompart, Jorge Gálvez, Ramón García-Domenech, Lemont B. Kier, M. Natália D. S. Cordeiro   +4 more
wiley   +1 more source

Novel high/low solubility classification methods for new molecular entities. [PDF]

Int J Pharm, 2016
Dave RA, Morris ME.
europepmc   +1 more source

A quantitative threshold for high/low extent of urinary excretion of compounds in humans. [PDF]

Biopharm Drug Dispos, 2016
Dave RA, Morris ME.
europepmc   +1 more source

Procainamide, but not N-acetylprocainamide, induces protein free radical formation on myeloperoxidase: a potential mechanism of agranulocytosis. [PDF]

Chem Res Toxicol, 2008
Siraki AG, Deterding LJ, Bonini MG, Jiang J, Ehrenshaft M, Tomer KB, Mason RP.   +6 more
europepmc   +1 more source

ABC of monitoring drug therapy. Measuring plasma drug concentrations. [PDF]

BMJ, 1992
Aronson JK, Hardman M.
europepmc   +1 more source

Are there environmental forms of systemic autoimmune diseases? [PDF]

Environ Health Perspect, 1999
Hess EV.
europepmc   +1 more source

Metabolites of procainamide and practolol inhibit complement components C3 and C4. [PDF]

Biochem J, 1988
Sim E, Stanley L, Gill EW, Jones A.
europepmc   +1 more source

BDDCS applied to over 900 drugs. [PDF]

AAPS J, 2011
Benet LZ, Broccatelli F, Oprea TI.
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Analysis of procainamide hydrochloride and acecainide hydrochloride in rat feed

Journal of Pharmaceutical Sciences, 1980
An extraction and GLC assay procedure was developed for quantitation of procainamide hydrochloride and acecainide hydrochloride in rat feed. 4-Amino-N-[2-(dipropylamino)ethyl]benzamide hydrochloride was synthesized and utilized as an internal standard.
J E, Carter, J S, Dutcher, D P, Carney, L R, Klein, L A, Black, P W, Erhardt   +5 more
openaire   +2 more sources

Acecainide pharmacokinetics in normal subjects of known acetylator phenotype

Biopharmaceutics & Drug Disposition, 1991
AbstractThe purpose of this study was to determine the pharmacokinetics of acecainide (formerly N‐acetylprocainamide) in six normal subjects of known acetylator phenotype. Three subjects were fast acetylators and three slow acetylators by sulfapyridine phenotyping criteria.
J D, Coyle, H, Boudoulas, J J, Lima
openaire   +2 more sources