Results 101 to 110 of about 40,837 (237)

Inpatient Cardiac Resynchronization Therapy During Heart Failure Hospitalization: A Distinct High‐Risk Phenotype

open access: yesPacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background The role of cardiac resynchronization therapy (CRT) during hospitalization for heart failure (HFH) is uncertain, because hospitalized patients were routinely excluded from landmark CRT trials. Despite this, CRT implantation during HFH is common.
Oliver Rees   +5 more
wiley   +1 more source

ACE-Inhibitor Related Angioedema Is Not Sufficiently Reported to the Danish Adverse Drug Reactions Database

open access: yesDrug, Healthcare and Patient Safety, 2019
Johan Emil Lundbek Cornwall,1 Anette Bygum,1,2 Eva Rye Rasmussen3 1Department of Dermatology and Allergy Centre, Odense University Hospital, Odense C 5000, Denmark; 2Department of Clinical Research, University of Southern Denmark, Odense, Denmark ...
Cornwall JEL, Bygum A, Rasmussen ER
doaj  

Mechanism‐Informed Pharmacotherapy Optimization and Deprescribing: A Redox–Mitochondrial Framework

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
From cumulative drug burden to mitochondrial stress and functional decline. The graphical abstract summarizes the central concept of the review, illustrating how cumulative pharmacotherapy exposure may contribute to redox–mitochondrial stress and thereby reduce biological and functional resilience.
Boštjan Martinc
wiley   +1 more source

Tirzepatide and SGLT2 Inhibitors for Heart Failure With Preserved Ejection Fraction and Obesity: Entering a New Cardiometabolic Therapeutic Era

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
Tirzepatide and SGLT2 inhibitors act through distinct but complementary mechanisms in obesity‐related HFpEF: tirzepatide targets adiposity, inflammation, and insulin resistance, while SGLT2 inhibitors improve decongestion, myocardial energetics, and cardiac remodeling.
Zakariye Isak Mohamed   +8 more
wiley   +1 more source

Molecular Mechanisms of Food Bioactive Constituents in the Management of Obesity and Hypertension: A Critical Review

open access: yesPhytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.
Obesity and hypertension co‐exist and share molecular mechanisms in terms of dietary therapy, modulated by food bioactive constituents. ABSTRACT Obesity and hypertension are among the most pressing global public health challenges. They frequently co‐exist, with obesity‐related hypertension accounting for an estimated 75% of the hypertension burden ...
Samuel Oluwasegun Maccarthy   +3 more
wiley   +1 more source

Digital Health Interventions to Improve Medication Adherence Among Older Adults: A Systematic Review

open access: yesAustralasian Journal on Ageing, Volume 45, Issue 3, September 2026.
ABSTRACT Objective To review evidence on the type, characteristics and effect of digital health interventions (DHIs) on medication adherence among older people. Methods Articles were searched from inception to May 2025 in PubMed, Embase, CINAHL, Scopus and Web of Science.
Kaleab Taye Haile   +7 more
wiley   +1 more source

Dynamic Risk Assessment for the Development of Persistent Atrial Fibrillation Using Statistical and Machine Learning Approaches

open access: yesAnnals of Noninvasive Electrocardiology, Volume 31, Issue 5, September 2026.
Machine learning using 6‐month rolling AF burden from cardiac implantable devices accurately predicts 1‐year progression to persistent atrial fibrillation. Higher AF intensity and frequency strongly identify high‐risk patients, enabling dynamic, point‐in‐time risk stratification to support earlier, targeted clinical intervention.
Alexei Nakonechnyi   +14 more
wiley   +1 more source

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