Results 1 to 10 of about 303,140 (239)
Pharmaceutics, 2021 Acid reducing agents (ARAs) reduce the dissolution rate of weakly basic drugs in the stomach potentially leading to lower bioavailability. Formulating the API as a rapidly dissolving salt is one strategy employed to reduce the impact of ARAs on ...
Siri Kalyan Chirumamilla +3 more
doaj +1 more source
Pharmaceutics, 2023 Imatinib is mainly metabolised by CYP3A4 and CYP2C8 and is extensively bound to α-acid glycoprotein (AAG). A physiologically based pharmacokinetic (PBPK) model for imatinib describing the CYP3A4-mediated autoinhibition during multiple dosing in ...
Karen Rowland Yeo +3 more
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Pharmaceutics, 2020 A physiologically based pharmacokinetic (PBPK) model of selegiline (SEL), and its metabolites, was developed in silico to evaluate the disposition differences between healthy and special populations.
Santosh Kumar Puttrevu +3 more
doaj +1 more source
Revista de História das Ideias, 2023 Múltiples e intrincadas fueron las causas que produjeron algo tan aberrante como el nacionalsocialismo. En el presente trabajo solo abordaremos ciertas cuestiones que tienen que ver con las raíces filosóficas y culturales del nazismo. Observaremos que, si bien es cierto que también surgieron filosofías irracionalistas en otras naciones de Europa, fue ...
openaire +3 more sources
Gamma-ray upper limits on magnetars with 6 years of Fermi-LAT observations [PDF]
, 2016 We report on the search for gamma-ray emission from 20 magnetars using 6 years of Fermi, Large Area Telescope (LAT) observations. No significant evidence for gamma-ray emission from any of the currently-known magnetars is found.
de Ona-Wilhelmi, Emma +3 more
core +5 more sources
A new nearby pulsar wind nebula overlapping the RX J0852.0-4622 supernova remnant [PDF]
, 2012 Energetic pulsars can be embedded in a nebula of relativistic leptons which is powered by the dissipation of the rotational energy of the pulsar.
Acero, F. +4 more
core +4 more sources
Journal of Nutritional Science, 2013 Dietary strategies for alleviating health complications associated with type 2 diabetes (T2D) are being pursued as alternatives to pharmaceutical interventions.
Nigel Hoggard +6 more
doaj +1 more source
An MHD study of SN 1006 and determination of the ambient magnetic field direction [PDF]
, 2010 In this work we employ an MHD numerical code to reproduce the morphology observed for SN 1006 in radio synchrotron and thermal X-ray emission. We introduce a density discontinuity, in the form of a flat cloud parallel to the Galactic Plane, in order to ...
De Colle, F +3 more
core +2 more sources
Desarrollo de aceros reforzados con carburos primarios vía metalurgia líquida
Revista de Metalurgia, 2005 Para que el reforzamiento de los aceros con carburos primarios vía metalurgia líquida sea técnicamente viable se requiere del desarrollo de un tipo de producto reforzante sólido, adecuado para su incorporación al acero, así como de la optimización de ...
I. Agote +7 more
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Estudio por difracción de rayos X de los productos de corrosión del acero al carbono
Revista de Metalurgia, 2003 En un estudio anterior se encontró que la tasa de corrosión, de un acero al carbono, decrecía cuando se le sometía al efecto combinado de una mezcla de contaminantes (SO4-2 = 10-4 M + Cl- = 1,5 x 10-3 M).
A. L. Morales
doaj +1 more source