Results 1 to 10 of about 43,801 (232)

Hyperpyrexia with hemodynamic instability after sublingual misoprostol: case report and literature review [PDF]

AJOG Global Reports
Misoprostol is widely used in obstetric practice for the prevention and treatment of postpartum hemorrhage due to its uterotonic efficacy, oral administration, and stability at room temperature. Although generally considered safe, rare but severe adverse
Paola A. Castellanos, MD, Juan C. Ureña, MD, Angie J. Acero, MD, Víctor S. Rangel, MD   +3 more
doaj   +2 more sources

Mechanistic PBPK Modelling to Predict the Advantage of the Salt Form of a Drug When Dosed with Acid Reducing Agents

Pharmaceutics, 2021
Acid reducing agents (ARAs) reduce the dissolution rate of weakly basic drugs in the stomach potentially leading to lower bioavailability. Formulating the API as a rapidly dissolving salt is one strategy employed to reduce the impact of ARAs on ...
Siri Kalyan Chirumamilla, Venkatesh Teja Banala, Masoud Jamei, David B. Turner   +3 more
doaj   +1 more source

Physiologically Based Pharmacokinetic Modelling to Predict Imatinib Exposures in Cancer Patients with Renal Dysfunction: A Case Study

Pharmaceutics, 2023
Imatinib is mainly metabolised by CYP3A4 and CYP2C8 and is extensively bound to α-acid glycoprotein (AAG). A physiologically based pharmacokinetic (PBPK) model for imatinib describing the CYP3A4-mediated autoinhibition during multiple dosing in ...
Karen Rowland Yeo, Oliver Hatley, Ben G. Small, Trevor N. Johnson   +3 more
doaj   +1 more source

Physiologically Based Pharmacokinetic Modeling of Transdermal Selegiline and Its Metabolites for the Evaluation of Disposition Differences between Healthy and Special Populations

Pharmaceutics, 2020
A physiologically based pharmacokinetic (PBPK) model of selegiline (SEL), and its metabolites, was developed in silico to evaluate the disposition differences between healthy and special populations.
Santosh Kumar Puttrevu, Sumit Arora, Sebastian Polak, Nikunj Kumar Patel   +3 more
doaj   +1 more source

Galeichthyinae Acero

, 2023
Subfamily Galeichthyinae Acero & Betancur-R., 2007 (Figs 1–3) Type genus: Galeichthys Valenciennes, 1840. Diagnosis (all of ambiguous optimization) Frontal mesial laminar projection absent (23, 1> 0); parieto-supraoccipital process base almost as narrow as posterior portion (46, 1> 0); ventral crest of parieto-supraoccipital process weakly developed ...
Marceniuk, Alexandre Pires, Oliveira, Claudio, Ferraris Jr, Carl J.   +2 more
openaire   +1 more source

Romanticismo de acero

Revista de História das Ideias, 2023
Múltiples e intrincadas fueron las causas que produjeron algo tan aberrante como el nacionalsocialismo. En el presente trabajo solo abordaremos ciertas cuestiones que tienen que ver con las raíces filosóficas y culturales del nazismo. Observaremos que, si bien es cierto que también surgieron filosofías irracionalistas en otras naciones de Europa, fue ...
openaire   +3 more sources

A single supplement of a standardised bilberry (Vaccinium myrtillus L.) extract (36 % wet weight anthocyanins) modifies glycaemic response in individuals with type 2 diabetes controlled by diet and lifestyle

Journal of Nutritional Science, 2013
Dietary strategies for alleviating health complications associated with type 2 diabetes (T2D) are being pursued as alternatives to pharmaceutical interventions.
Nigel Hoggard, Morven Cruickshank, Kim-Marie Moar, Charles Bestwick, Jens J. Holst, Wendy Russell, Graham Horgan   +6 more
doaj   +1 more source

Boración de aceros

, 2022
La boración es un tratamiento termoquímico controlado por la difusión. Consiste en la saturación con boro de la superficie de un metal o aleación, con objeto de aumentar su dureza y resistencia al desgaste y a la corrosión, principalmente en medios ácidos.
openaire   +2 more sources

Desarrollo de aceros reforzados con carburos primarios vía metalurgia líquida

Revista de Metalurgia, 2005
Para que el reforzamiento de los aceros con carburos primarios vía metalurgia líquida sea técnicamente viable se requiere del desarrollo de un tipo de producto reforzante sólido, adecuado para su incorporación al acero, así como de la optimización de ...
I. Agote, M. Gutiérrez, M. Orbegozo, M. Asensio, J. I. Erauskin, L. Á. Erausquin, J. I. Echeverría, J. Roncal   +7 more
doaj   +1 more source

Estudio por difracción de rayos X de los productos de corrosión del acero al carbono

Revista de Metalurgia, 2003
En un estudio anterior se encontró que la tasa de corrosión, de un acero al carbono, decrecía cuando se le sometía al efecto combinado de una mezcla de contaminantes (SO4-2 = 10-4 M + Cl- = 1,5 x 10-3 M).
A. L. Morales
doaj   +1 more source