Results 51 to 60 of about 23,022 (216)

Denosumab Offers Relatively Lower Initial Protection Against Osteoporotic Vertebral Fractures in Treatment‐Naive Patients Compared With Zoledronate

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
We compared the initial efficacy of denosumab (Dmab) and zoledronate (ZOL) in treatment‐naive patients with osteoporosis. This cohort study, based on TriNetX data, evaluated the risks of fractures and mortality using Kaplan–Meier survival analyses, with hazard ratios (HRs) and 95% confidence intervals (CIs).
Ko‐Hsiu Lu   +2 more
wiley   +1 more source

Preventing tibial and talar component contact during implantation of a total ankle replacement. [PDF]

open access: yes, 2013
27.03.15 KB. Ok to add embargo period passed (email from RCS) 05.03.15 KB. Emailed author re copyright. author does not have CTA. contact publisher. May have forgotten to do this.
AJ Roche   +2 more
core   +2 more sources

Treatment With Valoctocogene Roxaparvovec in a Patient With Severe Hemophilia A Led to Sustained Normal FVIII Levels

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Valoctocogene roxaparvovec, an adeno‐associated virus (AAV)‐based gene therapy, enables endogenous factor VIII (FVIII) expression in patients with severe hemophilia A without the need for regular FVIII infusions. Long‐term follow‐up assesses durability, safety, and immune‐related challenges following gene therapy.
Kerstin Herbst   +8 more
wiley   +1 more source

Three Year Experience of Treating the Acetabular Fracture with Reconstruction Plate at Civil Hospital Karachi [PDF]

open access: yesJLUMHS, 2019
OBJECTIVE: To evaluate the radiological outcomes and post-operative complications of Acetabular Fractures treated with reconstruction plates. METHODOLOGY: It was a prospective descriptive study conducted at the Department of Orthopaedic Surgery, Dow ...
Badaruddin Sahito   +4 more
doaj   +1 more source

Orthopaedic surgery [PDF]

open access: yes, 2005
Over the past fifty years orthopaedic surgery made giant strides forward. It developed from a discipline that dealt primarily with the treatment of fractures, bone infections and tendon transfers and that treated degenerate joints by fusing them to one ...
Grixti, Charles J.
core  

Evaluation for radiographic changes in the coxofemoral joint and proximal femur following intramedullary stabilisation of diaphyseal femoral fractures using angle‐stable interlocking nails in skeletally immature patients

open access: yesJournal of Small Animal Practice, EarlyView.
Objectives To evaluate a juvenile dog population that sustained diaphyseal femoral fractures surgically stabilised with an angle‐stable interlocking nail and evaluate for evidence of proximal femoral malformation both periooperatively and at skeletal maturity.
L. M. Meneghetti   +2 more
wiley   +1 more source

Finite element analysis of posterior acetabular column plate and posterior acetabular wall prostheses in treating posterior acetabular fractures

open access: yesJournal of Orthopaedic Surgery and Research, 2023
Background The purpose of this study was to investigate the mechanical stability of the posterior acetabular column plate and different posterior acetabular wall prostheses used in treating posterior acetabular fractures with or without comminution ...
Guixiong Huang   +6 more
doaj   +1 more source

Anatomical Study of Lateral Compression II Screw Path and Entry Parameters Based on Three‐Dimensional CT Image Reconstruction Techniques

open access: yesOrthopaedic Surgery, Volume 17, Issue 5, Page 1454-1463, May 2025.
This graphical abstract illustrates a study where 43 adult patients (21 males, 22 females) underwent CT scans to reconstruct 3D pelvic models using Mimics and 3‐Matic software. The analysis measured the Lateral Compression II (LC‐II) screw path, revealing sex‐based anatomical differences that could improve the precision and safety of percutaneous LC‐II
Xingye Du, Yong Liu, Xuefeng Jiang
wiley   +1 more source

Utility of 3D printed models as adjunct in acetabular fracture teaching for Orthopaedic trainees

open access: yesBMC Medical Education, 2022
Objective To evaluate the use of 3-D printed models as compared to didactic lectures in the teaching of acetabular fractures for Orthopaedic trainees.
S Goyal   +4 more
doaj   +1 more source

A Criterion of Reduction Quality of Femoral Neck Fractures Based on Spatial Residual Displacements of Femoral Head

open access: yesOrthopaedic Surgery, Volume 17, Issue 5, Page 1503-1512, May 2025.
The new reduction criterion of reduction quality was based on two indicators of residual displacements: the postoperative residual displacement of the center of the femoral head and the postoperative residual rotational displacement. When the postoperative residual displacement of the center of the femoral head is ≤ 10.22 mm, and the postoperative ...
Shuang‐Shuang Cui   +4 more
wiley   +1 more source

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