Results 11 to 20 of about 258,318 (261)

2-Azido-N-(4-methylphenyl)acetamide

IUCrData, 2022
The asymmetric unit of the title compound, C9H10N4O, comprises three independent molecules, two pairs of which differ significantly in the rotational orientation of the azido group and one pair having very similar conformations; the N—N—C—C torsion ...
Mohcine Missioui, Walid Guerrab, Abdulsalam Alsubari, Joel T. Mague, Youssef Ramli   +4 more
doaj   +1 more source

Synthesis of acetamides bearing 3-aryl-3,4-dihydroquinazolin-4-one and 2-thioxothiazolidin-4-one moieties as novel derivatives

Vietnam Journal of Science, Technology and Engineering, 2022
Five new derivatives of N-(4-oxo-2-thioxothiazolidin-3-yl)-2-((3-aryl-4-oxo-3,4-dihydroquinazolin-2-yl)thio) acetamides have been synthesized successfully through a four-step process from anthranilic acid and aryl isothiocyanates as starting materials ...
Tien Cong Nguyen, Duc Dung Pham, Thi Minh Dinh Tran, Thi Thuy Linh Bui   +3 more
doaj   +1 more source

N-(4-Methoxy-2-nitrophenyl)-2-(3-methyl-2-oxo-1,2-dihydroquinoxalin-1-yl)acetamide

IUCrData, 2023
The quinoxaline unit in the title molecule, C18H16N4O5, is slightly puckered [dihedral angle between the rings = 2.07 (12)°] while the whole molecule adopts an L-shaped conformation.
Mohcine Missioui, Joel T. Mague, Abdulsalam Alsubari, Mhammed Ansar, El Mokhtar Essassi, Youssef Ramli   +5 more
doaj   +1 more source

Rational Design, Synthesis and Biological Evaluation of Pyrimidine-4,6-diamine derivatives as Type-II inhibitors of FLT3 Selective Against c-KIT. [PDF]

, 2018
FMS-like Tyrosine Kinase 3 (FLT3) is a clinically validated target for acute myeloid leukemia (AML). Inhibitors targeting FLT3 have been evaluated in clinical studies and have exhibited potential to treat FLT3-driven AML.
Bharate, Jaideep B, Ding, Lucky, Frett, Brendan, Lakkaniga, Naga Rajiv, Li, Hong-Yu, McConnell, Nicholas, Naresh, Gunaganti, Shah, Neil P, Zhang, Lingtian   +8 more
core   +2 more sources

N-(Phenylsulfonyl)acetamide [PDF]

Acta Crystallographica Section E Structure Reports Online, 2010
In the title compound, C(8)H(9)NO(3)S, the N-H bond is in an anti-periplanar conformation with respect to the C=O bond. The crystal packing is stabilized by N-H⋯O hydrogen bonds, generating C(4) chains propagating in [001].
B. Thimme Gowda, Sabine Foro, P. G. Nirmala, Hartmut Fuess   +3 more
openaire   +3 more sources

A New Method to Overcome Carboxyamide Formation During AFEX Pretreatment of Lignocellulosic Biomass

Frontiers in Chemistry, 2022
Lignin-carbohydrate complexes (LCCs) in the plant cell wall are responsible for providing resistance against biomass-degrading enzymes produced by microorganisms.
Hui Dong, Leonardo da Costa Sousa, Bryan Ubanwa, A. Daniel Jones, A. Daniel Jones, Venkatesh Balan, Venkatesh Balan   +6 more
doaj   +1 more source

3,3′-[(Cyclohexane-1,4-diyl)bis(azanediyl)]bis(cyclohex-2-en-1-one)

IUCrData, 2016
The title compound, C18H26N2O2, crystallizes with two half-molecules in the asymmetric unit, both lying about inversion centres situated at the centers of the cyclohexane rings.
Antar A. Abdelhamida, Shaaban K. Mohamed, Jim Simpson   +2 more
doaj   +1 more source

Crystal structure of 2-cyano-N-(furan-2-ylmethyl)acetamide

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C8H8N2O2, the acetamide unit is inclined to the furan ring by 76.7 (1)°. In the crystal, molecules are linked by N—H...O and C—H...O hydrogen bonds, generating C(4) chains along [100].
Shivanna Subhadramma, Budanur Papaiah Siddaraju, Chandra Naveen, Janardhanan Saravanan, Dasararaju Gayathri   +4 more
doaj   +1 more source

Discovery of Potent Dual EGFR/HER2 Inhibitors Based on Thiophene Scaffold Targeting H1299 Lung Cancer Cell Line

Pharmaceuticals, 2020
Dual targeting of epidermal growth factor receptor (EGFR) and human EGFR-related receptor 2 (HER2) is a proven approach for the treatment of lung cancer. With the aim of discovering effective dual EGFR/HER2 inhibitors targeting non-small cell lung cancer
Ranza Elrayess, Yasmine M. Abdel Aziz, Mohamed Saleh Elgawish, Marwa Elewa, Asmaa S. A. Yassen, Sameh S. Elhady, Hosam A. Elshihawy, Mohamed M. Said   +7 more
doaj   +1 more source

Local electronic structure of the peptide bond probed by resonant inelastic soft X-ray scattering. [PDF]

, 2019
The local valence orbital structure of solid glycine, diglycine, and triglycine is studied using soft X-ray emission spectroscopy (XES), resonant inelastic soft X-ray scattering (RIXS) maps, and spectra calculations based on density-functional theory ...
Benkert, A, Blum, M, Bär, M, Hauschild, D, Heske, C, Meyer, F, Reinert, F, Weinhardt, L, Wilks, RG, Yang, W, Zharnikov, M   +10 more
core   +4 more sources