Results 101 to 110 of about 136,607 (334)

Aspirin inhibits the acute venodilator response to furosemide in patients with chronic heart failure [PDF]

, 2001
OBJECTIVES: We sought to determine the effect of aspirin on the venodilator effect of furosemide in patients with chronic heart failure (CHF) BACKGROUND: Furosemide has an acute venodilator effect preceding its diuretic action, which is blocked
Andrew P Davie, Bhatia, Biagi, Bippi, Brown, Brown, Cleland, Davie, Davie, Dikshit, Ellory, Gascho, Gimbrone, Goldiner, Guazzi, Harada, John J.V McMurray, Johnston, Johnston, Johnston, Johnston, Johnston, Jones, Jones, Liguori, Love, MacKay, Munzel, Pardeep S Jhund, Passmore, Pickkers, Tan, Weinstein, Whitney   +33 more
core   +1 more source

A novel clinical interprofessional education experience between pharmacy and dental students in an advanced geriatric surgical dental clinic

JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, EarlyView.
Abstract Introduction To address the opioid crisis in the United States, guidelines have prioritized non‐opioid therapies (i.e., non‐steroidal anti‐inflammatory drugs, acetaminophen), for postoperative dental pain. Complex cases may necessitate alternative analgesics, requiring careful pharmacotherapy management.
Justina Lipscomb, Kirk Evoy, Tam Van, Sorina Torrez, Kajal Bhatka, Rebecca Moote   +5 more
wiley   +1 more source

Soy isoflavones reduce acetaminophen-induced liver injury by inhibiting cytochrome P-450-mediated bioactivation and glutathione depletion and increasing urinary drug excretion in rats

Journal of Functional Foods, 2016
Soy isoflavones (SI) are phytochemicals with various biological activities. Acetaminophen can cause acute liver injury when overdosed. In this study, to investigate the effects of SI on the metabolism and toxicity of acetaminophen in liver, rats were fed
Yun-Ta Liu, Yu-Hua Chen, Naoto Uramaru, Ai-Hsuan Lin, Hui-Ting Yang, Chong-Kuei Lii, Hsien-Tsung Yao   +6 more
doaj  

Morphologic characteristic of the rat kidney after acetaminophen-induced nephrotoxicity on the background of alimentary deprivation of protein.

Морфологія, 2015
Background. Acetaminophen is known as inducer of acute hepatotoxicity. Extrahepatic manifestations of acetaminophen toxicity are poorly understood in particular its nephrotoxicity. Objective. The purpose of this study was the morphological characteristic
G. P. Kopylchuk, O. N. Voloshchuk, I. M. Buchkovskaia, I. S. Davydenko   +3 more
doaj   +1 more source

Timescale analysis of a mathematical model of acetaminophen metabolism andtoxicity [PDF]

, 2015
Acetaminophen is a widespread and commonly used painkiller all over the world. However, it can cause liver damage when taken in large doses or at repeated chronic doses.
Reddyhoff, D, Regan, S, Ward, J, Webb, SD, Williams, D   +4 more
core   +1 more source

Persistent AST Elevation in a Patient With Ovarian Cancer: A Rare Diagnostic Challenge

Journal of Clinical Laboratory Analysis, EarlyView.
ABSTRACT Background Persistent elevation of aspartate aminotransferase (AST) is commonly indicative of liver injury or disease, but isolated AST elevation without concurrent alanine aminotransferase (ALT) increase is rare and difficult to diagnose. While AST is non‐specific and found in various tissues, its isolated elevation is due to less common ...
Lechuang Chen, Yu Zhang, Qing H. Meng
wiley   +1 more source

Clinical Evaluation of Drug–Drug Interactions Between Bictegravir and Strong Inhibitors/Inducers of the CYP3A4, UGT1A1, or P‐gp Pathways

The Journal of Clinical Pharmacology, EarlyView.
Abstract In addition to antiretroviral therapy (ART), people with HIV often take medications to treat comorbidities. It is therefore important to assess these medications for potential drug‐drug interactions, which may affect the safety and efficacy of ART. Three phase I studies were conducted in adult participants without HIV. The pharmacokinetics (PK)
Priyanka Arora, Hui Liu, John Ling, Jason T. Hindman, Dhananjay D. Marathe   +4 more
wiley   +1 more source

Leptin receptor gene polymorphisms and sex modify the association between acetaminophen use and asthma among young adults: results from two observational studies

Respiratory Research, 2018
Background Epidemiologic studies have demonstrated associations between acetaminophen use and asthma. This investigation sought to determine whether sex modifies the acetaminophen-asthma association and whether leptin (LEP) and leptin receptor (LEPR ...
Ali H. Ziyab, Nandini Mukherjee, Ramesh J. Kurukulaaratchy, Hongmei Zhang, Susan Ewart, Hasan Arshad, Wilfried Karmaus   +6 more
doaj   +1 more source

Epidermolysis bullosa for primary care providers: A practical review

Journal of General and Family Medicine, EarlyView.
Abstract Epidermolysis bullosa (EB) is a group of genetic skin diseases, which manifest as fragile skin and blistering in addition to many extracutaneous conditions. Pediatricians and primary care providers play an integral role in managing these patients with multifaceted care needs.
Kennedy Sparling, Judith O'Haver, Muayad Shahin, Amanda Damon, Nichole Halliburton, Kellie Badger, Mariam Iqneibi, Beth Moeves, Harper N. Price, Emily S. Gorell   +9 more
wiley   +1 more source

Acetaminophen Metabolism in Man, as Determined by High-Resolution Liquid Chromatography [PDF]

, 1974
J.E. Mrochek, Sidney Katz, W. H. Christie, Stanley R Dinsmore   +3 more
openalex   +1 more source