Results 11 to 20 of about 938 (159)

Design and Synthesis of New Hydantoin Acetanilide Derivatives as Anti-NSCLC Targeting EGFRL858R/T790M Mutations

open access: yesPharmaceuticals, 2022
Epidermal Growth Factor Receptor (EGFR), its wild type and mutations L858R/T790M, is overexpressed in non-small cell lung cancer (NSCLC) patients and is considered an inevitable oncology target.
Moamen A. Hassanin   +5 more
doaj   +1 more source

Palladium-catalyzed ortho-halogenations of acetanilides with N-halosuccinimides via direct sp2 C–H bond activation in ball mills

open access: yesBeilstein Journal of Organic Chemistry, 2018
A solvent-free palladium-catalyzed ortho-iodination of acetanilides using N-iodosuccinimide as the iodine source has been developed under ball-milling conditions. This present method avoids the use of hazardous organic solvents, high reaction temperature,
Zi Liu, Hui Xu, Guan-Wu Wang
doaj   +1 more source

2,2-Dichloro-N-(2,5-dichlorophenyl)acetamide

open access: yesActa Crystallographica Section E, 2008
The conformation of the N—H bond in the title compound, C8H5Cl4NO, is syn to the 2-chloro substituent and anti to the 5-chloro substituent in the aromatic ring.
B. Thimme Gowda   +2 more
doaj   +1 more source

A challenging redox neutral Cp*Co(III)-catalysed alkylation of acetanilides with 3-buten-2-one: synthesis and key insights into the mechanism through DFT calculations

open access: yesBeilstein Journal of Organic Chemistry, 2018
Traditional, established palladium cross-coupling procedures are widely applied in complex molecule synthesis; however, there is a significant disadvantage in the requirement for pre-functionalised substrates (commonly halides/triflates).
Andrew Kenny   +5 more
doaj   +1 more source

2-Chloro-N-(2,4-dimethylphenyl)acetamide

open access: yesActa Crystallographica Section E, 2008
The conformation of the N—H bond in the structure of the title compound, C10H12ClNO, is syn to the ortho methyl group, similar to that observed with respect to the meta methyl group in 2-chloro-N-(3-methylphenyl)acetamide and the ortho-chloro group
B. Thimme Gowda   +2 more
doaj   +1 more source

TBHP-mediated highly efficient dehydrogenative cross-oxidative coupling of methylarenes with acetanilides

open access: yesBeilstein Journal of Organic Chemistry, 2016
A TBHP-mediated dehydrogenative cross-oxidative-coupling approach has been developed for the synthesis of N-arylbenzamides from methylarenes and acetanilides.
Cui Chen, Weibing Liu, Peng Zhou
doaj   +1 more source

2,2-Dichloro-N-(3-nitrophenyl)acetamide

open access: yesActa Crystallographica Section E, 2008
The conformation of the N—H bond in the structure of the title compound (3NPDCA), C8H6Cl2N2O3, is anti to the meta-nitro group, similar to that in the structures of 2-chloro-N-(3-nitrophenyl)acetamide (3NPCA) and 2,2,2-trichloro-N-(3-nitrophenyl ...
Hartmut Fuess   +2 more
doaj   +1 more source

ACUTE ACETANILID POISONING. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1906
C. H. M., male, aged 52, came to this city from his home in Idaho to visit relatives. While here he complained of severe headache most of the time. Not getting relief from ordinary "headache pills" and "headache powders," he went to one of the local drug stores and bought an ounce of acetanilid in powder, bulk, took it to the hotel at which he was ...
openaire   +1 more source

2-Chloro-N-(2,3-dichlorophenyl)acetamide

open access: yesActa Crystallographica Section E, 2008
The conformation of the N—H bond in the title compound (23DCPCA), C8H6Cl3NO, is syn to both the 2- and 3-chloro substituents in the aromatic ring, similar to the 2-chloro substituent in 2-chloro-N-(2-chlorophenyl)acetamide (2CPCA), the 2- and 3 ...
Hartmut Fuess   +2 more
doaj   +1 more source

N-(3,4-Dimethylphenyl)acetamide

open access: yesActa Crystallographica Section E, 2008
The conformation of the N—H bond in the title compound (34DMPA), C10H13NO, is syn to the 3-methyl substituent in the aromatic ring, in contrast to the anti conformation observed with respect to the 3-chloro substituent in N-(3,4-dichlorophenyl ...
B. Thimme Gowda   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy