Results 71 to 80 of about 9,393 (260)

Photocatalytic Three-Component Synthesis of 3‑Heteroarylbicyclo[1.1.1]pentane-1-acetates

open access: yes
Herein, we report a visible-light-induced three-component reaction involving [1.1.1]­propellane, diazoates, and various heterocycles for the synthesis of 3-heteroarylbicyclo[1.1.1]­pentane-1-acetates. Throughout this reaction, the radicals generated from
Guoxiang Bao (15927899)   +9 more
core   +1 more source

Concerted catalytic reactions for conversion of ketones or enol acetates to chiral acetates

open access: yes, 2019
[GRAPHICS] Enol acetates or ketones asymmetrically transformed to chiral acetates in high yields with high optical purities through multistep reactions catalyzed by a lipase and a ruthenium complex.
Kim, MJ, Jung, HM, Park, J, Koh, JH
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Enzymatic Cleavage of Aryl Acetates

open access: yes, 2016
Seven enzymes have been screened for the cleavage of aryl acetates. Phenyl and naphthyl acetates react with lipases and esterases, whereas the sterically demanding anthracene acetate gave a conversion only with porcine liver esterase and esterase 2 from ...
Marcel Bauch   +7 more
core   +1 more source

Mode of attack of hydriodic acid on unsaturated glyceryl ethers

open access: yesJournal of Lipid Research, 1965
The mode of action of hydriodic acid (HI) on a sample rich in selachyl alcohol [1-O-9(cis)-octadecenyl glycerol] has been studied. HI attacked the olefinic bonds as well as the ether bonds, with the formation of at least two diiodides as well as the ...
Donald J. Hanahan
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

DBU-mediated C-C bond formation between Baylis-Hillman acetates and active methylene compounds

open access: yes
225-231A new reagent system for the formation of C-C bond between the Baylis-Hillman acetates and active methylene compounds (AMCs) has been developed. This method provides tri-substituted alkenes as the major product in good yield under neat condition.
Tashi Khom, Sonam   +2 more
core   +1 more source

Cobalt-catalyzed carboxylation of propargyl acetates with carbon dioxide. [PDF]

open access: yes, 2014
The cobalt-catalyzed carboxylation of propargyl acetates with CO2 (1 atm) is described. The reaction proceeds at room temperature in the presence of Mn powder as a reducing reagent. Various propargyl acetates are converted to the corresponding carboxylic
Terao, Jun   +7 more
core   +1 more source

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