Results 61 to 70 of about 25,448 (310)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Rhodium-Catalyzed Enantioselective Hydrogenation of Oxime Acetates

open access: yes, 2016
Rh-catalyzed enantioselective hydrogenation of oxime acetates was first reported, which afforded a new approach for chiral amine ...
Xumu Zhang (1447558)   +3 more
core   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Iron‐Catalyzed Cross‐Coupling of Alkenyl Acetates

open access: yes, 2015
Stable CO linkages are generally unreactive in cross-coupling reactions which mostly employ more electrophilic halides or activated esters (triflates, tosylates).
Stein, André Luiz   +4 more
core   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Mode of attack of hydriodic acid on unsaturated glyceryl ethers

open access: yesJournal of Lipid Research, 1965
The mode of action of hydriodic acid (HI) on a sample rich in selachyl alcohol [1-O-9(cis)-octadecenyl glycerol] has been studied. HI attacked the olefinic bonds as well as the ether bonds, with the formation of at least two diiodides as well as the ...
Donald J. Hanahan
doaj   +1 more source

Selective Cross-Coupling of Organic Halides with Allylic Acetates

open access: yes, 2016
A general protocol for the coupling of haloarenes with a variety of allylic acetates is presented. Strengths of the method are a tolerance for electrophilic (ketone, aldehyde) and acidic (sulfonamide, trifluoroacetamide) substrates and the ability to ...
Michael R. Prinsell (1342347)   +2 more
core   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Transition metal acetates

open access: yes, 1968
Some anhydrous transition metal acetates (Mn(II), Co(II), Cu(II), Ni(II), Zn(II), Ag(I), Mo(II), Ce(III), La(III)) have been prepared and their infrared spectra measured in the solid state.
R. N. Hayward, D. A. Edwards
core   +1 more source

Cobalt-catalyzed carboxylation of propargyl acetates with carbon dioxide. [PDF]

open access: yes, 2014
The cobalt-catalyzed carboxylation of propargyl acetates with CO2 (1 atm) is described. The reaction proceeds at room temperature in the presence of Mn powder as a reducing reagent. Various propargyl acetates are converted to the corresponding carboxylic
Terao, Jun   +7 more
core   +1 more source

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