Results 241 to 250 of about 32,023 (271)
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Acetazolamide in Phenobarbital Intoxication
Archives of Internal Medicine, 1966THE BARBITURATES can be divided into two groups on the basis of their metabolism. One group is metabolized primarily by the liver. The short-acting drugs, in general, fit into this group. The second group comprises those barbiturates in which elimination of the active agent is primarily by renal excretion with inactivation by the liver being of less ...
Morton F. Mason +3 more
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Effectiveness of Generic Acetazolamide
Archives of Ophthalmology, 1982Comparisons were made between the ocular hypotensive effects and blood levels achieved with the single-dose administration of either generic acetazolamide or brand-name acetazolamide (Diamox). The relative cost of the two products was surveyed. The effect of food on the absorption of acetazolamide was also evaluated.
Patrick K. Price +3 more
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Acetazolamide in the Treatment of Seizures
Annals of Pharmacotherapy, 1996OBJECTIVE: TO summarize the pharmacology, pharmacokinetics, efficacy, and safety of acetazolamide and to evaluate its therapeutic role in patients with epilepsy. DATA SOURCES: A computerized search of the MEDLINE (OVID) database (1966–1994) was used to identify publications regarding acetazolamide.
William G. Reiss, Karen S. Oles
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Acetazolamide poisoning in a toddler
Journal of Paediatrics and Child Health, 2001Abstract: Acetazolamide ingestion and its sequelae have not been previously reported in children. A 12‐month‐old girl, weighing 10 kg, developed metabolic acidosis following ingestion of between 500 and 1250 mg of acetazolamide. The maximum base deficit recorded was 11.6. She was treated with sodium bicarbonate and recovered completely.
Baer, E., Reith, D. M.
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American Journal of Obstetrics and Gynecology, 1962
Abstract A case of severe transient myopia following the use of acetazolamide is reported. The myopia was reproducible upon repeated administration of the drug. The myopia lasted 5 days in the first instance and only 3 days in the second instance. Previously the patient had taken acetazolamide without any ill effect, implying that the acute myopia ...
Kenneth E. Guenter +2 more
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Abstract A case of severe transient myopia following the use of acetazolamide is reported. The myopia was reproducible upon repeated administration of the drug. The myopia lasted 5 days in the first instance and only 3 days in the second instance. Previously the patient had taken acetazolamide without any ill effect, implying that the acute myopia ...
Kenneth E. Guenter +2 more
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MONITORING ACETAZOLAMIDE TREATMENT
Acta Ophthalmologica, 1982Electron capture gas chromatography was used to determine plasma concentrations after various doses of acetazolamide. In 40 patients steady state plasma concentrations were determined for daily doses of 187.5, 375, 750, and 1000 mg. Mean plasma concentrations increased with increasing dosages but there were marked interindividual variations.
Per Hartvig +3 more
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Bioavailability of Acetazolamide Tablets
Journal of Pharmaceutical Sciences, 1978Plasma acetazolamide levels were measured by an enzymatic assay following single 250-mg oral tablet doses to 20 healthy volunteers; five different lots of acetazolamide tablets from a single manufacturer were used in a balanced incomplete block design.
Ashok C. Shah +4 more
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Chronic Acetazolamide Intoxication
Journal of Toxicology: Clinical Toxicology, 1984Severe acidosis associated with acetazolamide therapy is rare. We report the first case in which plasma and whole blood acetazolamide concentrations were measured. A 61 year-old patient receiving oral acetazolamide for treatment of glaucoma presented with a 7 day history of declining mental status.
James C. Garrelts +5 more
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Nonlinear Model for Acetazolamide
Journal of Pharmaceutical Sciences, 1979Intravenous bolus injections of 14C-labeled acetazolamide were made in rabbits. Plasma, urine, and washed red blood cell concentrations were measured, the latter indicating bound drug. AUTOAN and NONLIN were used to fit the plasma data to a linear two-compartment model.
Albert M. Mattocks, Robert L. Kunka
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