Crystallization of the FAD-independent acetolactate synthase ofKlebsiella pneumoniae [PDF]
Acta Crystallographica Section D: Biological Crystallography, 2002 Leucine and valine are formed in a common pathway from pyruvate in which the first intermediate is 2-acetolactate. In some bacteria, this compound also has a catabolic fate as the starting point for the butanediol fermentation.
Siew Siew Pang +2 more
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HERBICIDES THAT INHIBIT ACETOLACTATE SYNTHASE [PDF]
Frontiers of Agricultural Science and Engineering, 2022 Herbicides are an essential pillar in modern agricultural practice. They are used to selectively reduce the growth of weeds in crops and natural environments. Early weed mitigating chemicals date back to Roman times and include substances as simple as table salt, sulfuric acid and carbon bisulfide.
Thierry LONHIENNE, Mario Daniel GARCIA, Yu Shang LOW, Luke W. GUDDAT
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Redirection of the Reaction Specificity of a Thermophilic Acetolactate Synthase toward Acetaldehyde Formation. [PDF]
PLoS ONE, 2016 Acetolactate synthase and pyruvate decarboxylase are thiamine pyrophosphate-dependent enzymes that convert pyruvate into acetolactate and acetaldehyde, respectively.
Maria Cheng +4 more
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Impact of acetolactate synthase inactivation on 1,3-propanediol fermentation by Klebsiella pneumoniae. [PDF]
PLoS ONE, 2019 1,3-Propanediol (1,3-PDO) is an important compound that is mainly used in industry for polymer production. Fermentation of 1,3-PDO from glycerol by Klebsiella pneumoniae is accompanied by formation of 2,3-butanediol (2,3-BDO) as one of the main byproduct.
Sheng Zhou +6 more
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Sunflower resistance to acetolactate synthase-inhibiting herbicides
Pesquisa Agropecuária Tropical, 2012 Sunflower is very sensitive to herbicides applied in post-emergence to control broad-leaf weeds. Researchers have developed herbicide-resistant genotypes to imidazolinone herbicides.
Alexandre Magno Brighenti
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The oxygenase reaction of acetolactate synthase detected by chemiluminescence [PDF]
FEBS Letters, 1994 In addition to the synthesis of ketolacids the enzyme acetolactate synthase shows an oxygen‐consuming side reaction. Partially purified acctolactate synthase from corn (Zea mays L.) and barley (Hordeum vulgare L.) exhibits chemiluminescence in the presence of oxygen, Mn2+ and low concentrations of pyruvate. Light emission is inhibited by azide, but not
Peter Böger
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Structure-Based Design of Acetolactate Synthase From Bacillus licheniformis Improved Protein Stability Under Acidic Conditions [PDF]
Frontiers in Microbiology, 2020 Catabolic acetolactate synthase (cALS) plays a crucial role in the quality of liquor because of its ability to catalyze the synthesis of the endogenous precursor product α-acetolactate of the aromatic compound tetramethylpyrazine (TTMP) and acetoin ...
Ting Zhao +8 more
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The Staphylococcus aureus α-Acetolactate Synthase ALS Confers Resistance to Nitrosative Stress [PDF]
Frontiers in Microbiology, 2017 Staphylococcus aureus is a worldwide pathogen that colonizes the human nasal cavity and is a major cause of respiratory and cutaneous infections. In the nasal cavity, S.
Sandra M. Carvalho +4 more
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Effect of Plant Growth-Promoting Bacteria on Antioxidant Status, Acetolactate Synthase Activity, and Growth of Common Wheat and Canola Exposed to Metsulfuron-Methyl [PDF]
Journal of XenobioticsMetsulfuron-methyl, a widely used herbicide, could cause damage to the sensitive plants in crop-rotation systems at extremely low levels in the soil. The potential of plant growth-promoting bacteria (PGPB) for enhancing the resistance of plants against ...
Margarita Bakaeva +5 more
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Identification and evaluation of novel acetolactate synthase inhibitors as antifungal agents. [PDF]
Antimicrob Agents Chemother, 2013 ABSTRACT High-throughput phenotypic screening against the yeast Saccharomyces cerevisiae revealed a series of triazolopyrimidine-sulfonamide compounds with broad-spectrum antifungal activity, no significant cytotoxicity, and low protein binding.
Richie DL +18 more
europepmc +4 more sources