Results 231 to 240 of about 2,532,893 (407)

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

Perspectives on the α5 nicotinic acetylcholine receptor in lung cancer progression. [PDF]

Front Cell Dev Biol
Cai J, Wang J, Wang Z, Wang J, Jia Y, Ma X.   +5 more
europepmc   +1 more source

The physiological role of three acetylcholine receptors in synaptic transmission in Aplysia

, 1972
Jacsue Kehoe
openalex   +1 more source

Localization of acetylcholine receptor in excitable membrane from the electric organ of Torpedo: Evidence for exposure of receptor antigenic sites on both sides of the membrane. [PDF]

, 1978
R Tarrab-Hazdai, Benjamin Geiger, Sara Fuchs, Abraham Amsterdam   +3 more
openalex   +1 more source

Gating Movement of Acetylcholine Receptor Caught by Plunge-Freezing

Journal of Molecular Biology, 2012
N. Unwin, Y. Fujiyoshi
semanticscholar   +1 more source

Cholinergic System Changes in Dopa‐Unresponsive Freezing of Gait in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Freezing of gait (FoG) is a debilitating mobility disturbance that becomes increasingly resistant to dopaminergic pharmacotherapies with advancing Parkinson's disease (PD). The pathophysiology underlying the response of FoG to dopaminergic treatment is poorly understood.
Kelvin L. Chou, Prabesh Kanel, Miriam van Emde Boas, Stiven Roytman, Giulia Carli, Roger L. Albin, Nicolaas I. Bohnen   +6 more
wiley   +1 more source

Molecular insights into the α6β4 nicotinic acetylcholine receptor function and ligand recognition. [PDF]

Nat Commun
Su J, Yu Z, Yin Z, Zhang Z, Zhao J, Meng Y, Li R, Gao Y, Zhang H, Yu R, Zhao Y.   +10 more
europepmc   +1 more source

Studies of human myasthenia gravis: electrophysiological and ultrastructural evidence compatible with antibody attachment to acetylcholine receptor complex. [PDF]

, 1976
John E. Rash, E X Albuquerque, C. S. Hudson, RichardF Mayer, John R. Satterfield   +4 more
openalex   +1 more source

Reading Difficulty of Online Patient Education Materials for Procedures in Dermatology

JEADV Clinical Practice, EarlyView.
Elizabeth Botto, Nicole Natarelli, Emily Coughlin, Lilia Correa‐Selm   +3 more
wiley   +1 more source

Surprises From the Basal Ganglia: Stop and Go Have New Meaning

Movement Disorders, EarlyView.
Abstract This perspective highlights new work suggesting the need for revision of the canonical direct–indirect model of the basal ganglia's influence on movement, with fresh evidence that there is a formerly unappreciated pair of direct and indirect pathways that parallel the standard model's canonical direct and indirect pathways, and promising ...
Ann M. Graybiel
wiley   +1 more source