Results 261 to 270 of about 223,570 (353)

Effect of the Arg16Gly β2‐Adrenergic Receptor Polymorphism on Long‐Term Mepolizumab Response and Clinical Remission in Severe Eosinophilic Asthma: A Genotype‐Stratified, Multicenter Study

Allergy, EarlyView.
This study examines the association between the rs1042713 (Arg16Gly) polymorphism of the β2‐adrenergic receptor and the risk of severe eosinophilic asthma, as well as its influence on mepolizumab long‐term effectiveness and clinical remission. The Arg16 allele is associated with increased risk of severe disease and potentially diminished long‐term ...
Santi Nolasco, Evelina Fagone, Raffaele Campisi, Andrea Portacci, Giulia Scioscia, Corrado Pelaia, Angelantonio Maglio, Claudio Candia, Vitaliano Nicola Quaranta, Isabella Carrieri, Alessandro Saglia, Alessandro Vatrella, Girolamo Pelaia, Carlo Vancheri, Maria Pia Foschino Barbaro, Maria D'Amato, Giovanna Elisiana Carpagnano, Nunzio Crimi, Claudia Crimi, on behalf of the Southern Italy Network on Severe Asthma Therapy, Rossella Intravaia, Morena Porto, Pietro Impellizzeri, Maria Provvidenza Pistorio, Fabio Vignera, Andrea Alessia Nardo, Concetta Giannì, Silvano Dragonieri, Flogerta Sana, Valeria Pezzuto, Santina Ferulli, Massimo Triggiani, Roberta Parente, Pasquale Tondo, Piera Soccio, Donato Lacedonia, Luigi Ciampo, Antonio Franzese, Valeria Longobardi   +38 more
wiley   +1 more source

Research progress in myocardial function and diseases related to muscarinic acetylcholine receptor (Review). [PDF]

Int J Mol Med
Shen C, Zuo Q, Shao Z, Lin Y, Chen S.
europepmc   +1 more source

Use of Acetylcholine Binding Protein in the Search for Novel α7 Nicotinic Receptor Ligands. In Silico Docking, Pharmacological Screening, and X-ray Analysis

, 2009
Chris Ulens, Atilla Akdemir, Aldo Jongejan, René van Elk, Sonia Bertrand, Anastassis Perrakis, Rob Leurs, August B. Smit, Titia K. Sixma, Daniel Bertrand, Iwan J. P. de Esch   +10 more
openalex   +2 more sources

Effect of Functional Electrical Stimulation Combined With Physical Exercise on Electron Transport Chain Activity in Peripheral Blood Cells of Stroke Patients

Artificial Organs, EarlyView.
Stroke induces mitochondrial dysfunction and motor disorders. FES combined with physical exercises can help restore mitochondrial function by regulating the formation of reactive oxygen species and, consequently, contributing to functional recovery. ABSTRACT Background Stroke is commonly accompanied by motor disorders secondary to the initial injury ...
A. Larrea, A. Martín‐Odriozola, E. Astigarraga, C. Rodríguez‐de‐Pablo, G. Barreda‐Gómez, M. Torrecilla   +5 more
wiley   +1 more source

Refinement of the rat acetylcholine receptor-specific passive transfer myasthenia gravis model using subcutaneous injections: an update to the guidelines. [PDF]

Sci Rep
Arets B, Mané-Damas M, Schöttler AK, Sikorski PM, Kusner LL, Kaminski HJ, Losen M, Martinez-Martinez P.   +7 more
europepmc   +1 more source

State-dependent binding of cholesterol and an anionic lipid to the muscle-type Torpedo nicotinic acetylcholine receptor [PDF]

Anna Ananchenko, Rui Yan Gao, François Dehez, John E. Baenziger   +3 more
openalex   +1 more source

Vasoreactivity as a Measure of Kidney Viability During Ex Vivo Normothermic Machine Perfusion

Artificial Organs, EarlyView.
This study aimed to investigate the influence of warm ischemic injury on renal vascular responsiveness to vasoactive drugs during normothermic machine perfusion (NMP). We found that the vascular responses to dopamine and norepinephrine could be used as objective indicators to assess kidney viability during NMP.
Isa M. van Tricht, Baran Ogurlu, Silke S. M. Wolfswinkel, Henri G. D. Leuvenink, Cyril Moers   +4 more
wiley   +1 more source

The Science of Pseudoaccommodation and Its Therapeutic Potential. [PDF]

Clin Ophthalmol
Poliński J, Walasik-Szemplińska D, Skrzypecki J.   +2 more
europepmc   +1 more source

Electrical Stimulation of Denervated Muscle: A Narrative Review

Artificial Organs, EarlyView.
This review explores existing strategies for stimulating denervated muscle following lower motor neuron injury, including direct electrical stimulation of the muscle and artificial reinnervation to enable more comfortable and efficient indirect functional muscle stimulation.
Linshan Chu, Jonathan C. Jarvis, Brian J. Andrews, James J. FitzGerald   +3 more
wiley   +1 more source

Genetic and pharmacological targeting of nicotinic acetylcholine receptor action blocks tumor progression in mouse models of breast cancer. [PDF]

J Immunol
Heard MA, Qian J, Sayeed S, Mechlowicz S, Zhang Q, Yeluri S, Pool K, Yamane R, Morris GP, Eliceiri BP.   +9 more
europepmc   +1 more source