THE EFFECT OF SALICYLATES ON THE ELECTROLYTE STRUCTURE OF THE BLOOD PLASMA. II. THE ACTION OF THERAPEUTIC DOSES OF SODIUM SALICYLATE AND OF ACETYLSALICYLIC ACID IN MAN1 [PDF]
, 1945 George M. Guest +2 more
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Identifying Drugs Associated With Parkinson's Disease Risk Using Machine Learning
Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.ABSTRACT Machine learning (ML)–based methods have been proposed as a potential approach for identifying candidate drugs to be repurposed as disease‐modifying treatments for Parkinson's disease (PD). We applied an ML‐based signal detection method to identify drugs associated with PD and evaluated the method's generalizability.
Eeva Pylkkö +8 more
wiley +1 more source
Analgesic and Anti-inflammatory Activity of Teucrium chamaedrys Leaves Aqueous Extract in Male Rats [PDF]
, 2010 Objective(s)Current study was undertaken to investigate the analgesic and anti-inflammatory effects of the aqueous extract of Teucrium chamaedrys in mice and rats.
Ali Pourmotabbed +3 more
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British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 329-347, February 2026.Clopidogrel, an antiplatelet agent, is currently licensed in the United Kingdom for the prevention and treatment of atherothrombotic events in cerebrovascular disease, coronary artery disease and peripheral arterial disease. Clopidogrel requires metabolic activation by the cytochrome P450 enzyme CYP2C19 to be effective.
Cinzia Dello Russo +22 more
wiley +1 more source
Acetylsalicylic acid in the treatment of cardiovascular diseases
КардиоСоматика, 2015 The problem of atherothrombosis and associated diseases is examined here. The estimation of an enteric form of acetylsalicylic acid (a drug Thrombo ASS) from the perspective of evidence-based medicine is also discussed. The use of acetylsalicylic acid in
V. S Zadionchenko +4 more
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Effect of administration of acetylsalicylic acid on phosphatase enzymes in liver of metabisulphite treated rats [PDF]
, 2009 J. E. Olajide +3 more
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Metformin‐Mediated Glycaemic Regulation as a Potential Strategy for Breast Cancer Prevention
Cancer Medicine, Volume 15, Issue 2, February 2026.Metformin (MET), a common antihyperglycemic drug, shows promising anti‐cancer effects in breast cancer (BC). It activates adenosine monophosphate‐activated protein kinase (AMPK), regulating cellular energy and inducing cell cycle arrest, anti‐proliferation, and microenvironment alterations.
Ambulugala Gamage Rajika Greshamali Jinadasa +4 more
wiley +1 more source
Synthesis, characterization and pharmacological evaluation of palmitic acid derivatives of salicylic acid and anthranilic acid [PDF]
, 2012 In the present study, salicylic acid and anthranilic acid were modified as lipids palmitoylsalicylic acid (PSA) and N-palmitoylanthranilic acid (N-PAA) by a simple esterification/amidation reaction of the resp. acid with palmitoyl chloride.
Harish Metticule Rao, S. +3 more
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