Results 21 to 30 of about 35,237 (157)

Assessment of Erythrocytes as a Model for In Vitro Drug Toxicity

Fountain Journal of Natural and Applied Sciences (FUJNAS), 2013
Mitochondria and lysosome have been used to study drug-cell interactions both in vitro and in vivo. However, their preparations to free them from other sub-cellular organelles are tedious and cumbersome.
M. A. Akanji, O. B. Ojewuyi, M. T. Yakubu   +2 more
doaj   +1 more source

Effect of systemic anticoagulant (acetyl-salicylic acid) application on implant osseointegration in rat tibias in allogeneic bone transplantation

Revista Científica
The aim of this study is to investigate the effect of systemic ad- ministration of acetylsalicylic acid, used in the treatment of coronary artery disease, on the level of osseointegration of titanium implants in the transplanted bone in the treatment of
Mehmet Gul, Murat Tanrisever, Delil Dogan, Merve Guney, Ozmen Istek, Umit Koray Can, Erhan Cahit Ozcan, Serkan Dundar   +7 more
doaj   +1 more source

Polyphenols of Salix aegyptiaca modulate the activities of drug metabolizing and antioxidant enzymes, and level of lipid peroxidation

BMC Complementary and Alternative Medicine, 2018
Background Salix aegyptiaca is known for its medicinal properties mainly due to the presence of salicylate compounds. However, it also contains other beneficial phytochemicals such as gallic acid, quercetin, rutin and vanillin.
Mohd Nauman, R. K. Kale, Rana P. Singh
doaj   +1 more source

ANTITROMBOTIC ACTIVITY OF A NEW BENZIMIDAZOLE DERIVATIVE WITH A SPATIALLY DIFFICULT PHENOLIC SUBSTITUTE IN ITS STRUCTURE

Фармация и фармакология (Пятигорск), 2020
The aim of the study was to investigate antithrombogenic properties of compound RU-1144 with previously identified pronounced antiplatelet and antioxidant activities.
Alexander A. Spasov, Aida F. Kucheryavenko, Ksenia A. Gaidukova, Maxim V. Chernikov, Olga N. Zhukovskaya   +4 more
doaj   +1 more source

The stability and degradation kinetics of acetylsalicylic acid in different organic solutions revisited – an UHPLC–ESI-QTOF spectrometry study

Current Issues in Pharmacy and Medical Sciences, 2016
Ultra high performance liquid chromatography (UHPLC), coupled with accurate quadrupole-time-of-flight (Q-TOF) mass spectrometry, was used for the stability study of acetylsalicylic acid within a variety of different organic solutions: methanol, ethanol ...
Skibinski Robert, Komsta Lukasz
doaj   +1 more source

A Simple and Cost-Effective TLC-Densitometric Method for the Quantitative Determination of Acetylsalicylic Acid and Ascorbic Acid in Combined Effervescent Tablets

Molecules, 2018
A new, simple, and cost-effective TLC-densitometric method has been established for the simultaneous quantitative determination of acetylsalicylic acid and ascorbic acid in combined effervescent tablets.
Alina Pyka-Pająk, Małgorzata Dołowy, Wioletta Parys, Katarzyna Bober, Grażyna Janikowska   +4 more
doaj   +1 more source

A Study on Pharmacokinetics of Acetylsalicylic Acid Mini-Tablets in Healthy Adult Males—Comparison with the Powder Formulation

Pharmaceutics, 2023
Children with Kawasaki disease are prescribed acetylsalicylic acid powder as an antipyretic analgesic and antiplatelet agent; however, some of it remains in the mouth, leading to a bitter or sour taste.
Noriko Hida, Taigi Yamazaki, Yoshiaki Fujita, Hidehiro Noda, Takehiko Sambe, Kakei Ryu, Takuya Mizukami, Sachiko Takenoshita, Naoki Uchida, Akihiro Nakamura, Tsutomu Harada   +10 more
doaj   +1 more source

Development and validation of liquid chromatography method for determination of acetylsalicylic and salicylic acid in dosage forms [PDF]

Arhiv za farmaciju, 2018
Acetylsalicylic acid belongs to nonsteroidal anti-inflammatory drugs with antiinflammatory, analgesic and antipyretic properties. The aim of this work was development and validation of HPLC method for qualitative and quantitative analysis of ...
Damnjanović Danijela, Dobričić Vladimir, Čudina Olivera, Vladimirov Sote   +3 more
doaj   +1 more source

DEFINITION OF ACTIVATED THROMBOCYTE NUMBER WITH ANTIBODIES FOR ACTIVATED FIBRINOGEN AND P-SELECTIN IN PATIENTS WITH ESSENTIAL THROMBOCYTHEMIA AND ANTIAGGREGATION DRUG EFFECT

Zdravniški Vestnik, 2004
Background. Essential thrombocythemia (ET) is a chronic myeloproliferative disease with a platelet count within the range of 400–2000 × 109/L. Higher percentage of platelets in the circulation of patients with ET express also activation markers on their ...
Samo Zver, Darja Žontar
doaj  

Influence of IL-β, IL-1RN, and TNF-α variants on the risk of acetylsalicylic acid-induced upper gastrointestinal bleeding: a case-control study [PDF]

Einstein (São Paulo)
Objective The use of acetylsalicylic acid, even in low doses, may be associated with the onset of upper gastrointestinal bleeding as an idiosyncratic response.
Marcela Forgerini, Cleslei Fernando Zanelli, Sandro Roberto Valentini, Patrícia de Carvalho Mastroianni   +3 more
doaj   +1 more source