Results 11 to 20 of about 61,991 (198)
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Hepatology, EarlyView., 2022 Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
N-acetylcholinesterase-induced apoptosis in Alzheimer's disease. [PDF]
PLoS ONE, 2008 BackgroundAlzheimer's disease (AD) involves loss of cholinergic neurons and Tau protein hyper-phosphorylation. Here, we report that overexpression of an N-terminally extended "synaptic" acetylcholinesterase variant, N-AChE-S is causally involved in both ...
Debra Toiber +5 more
doaj +1 more source
Acta Pharmaceutica Sinica B, 2020 Acetylcholine (ACh) regulates inflammation via α7 nicotinic acetylcholine receptor (α7 nAChR). Acetylcholinesterase (AChE), an enzyme hydrolyzing ACh, is expressed in immune cells suggesting non-classical function in inflammatory responses.
Etta Y.L. Liu +8 more
doaj +1 more source
A Computational Model of a Descending Mechanosensory Pathway Involved in Active Tactile Sensing. [PDF]
PLoS Computational Biology, 2015 Many animals, including humans, rely on active tactile sensing to explore the environment and negotiate obstacles, especially in the dark. Here, we model a descending neural pathway that mediates short-latency proprioceptive information from a tactile ...
Jan M Ache, Volker Dürr
doaj +1 more source
Jornal de Assistência Farmacêutica e FarmacoeconomiaIntrodução: O impacto ambiental dos inaladores pressurizados dosimetrados (pMDIs), amplamente usados no tratamento de doenças respiratórias, tem gerado crescente preocupação em saúde pública e ambiental.
Rodrigo Torres Scabello +6 more
doaj +1 more source
BiosensorsTaste masking in pharmaceutical products is a complex and subjective process that requires reliable evaluation methods. This review focuses on the electronic tongue (e-tongue), an emerging sensor-based technology designed to mimic human taste perception ...
Juliana Luz Melo Gongoni +3 more
doaj +1 more source
Areté, 2021 El siguiente trabajo se propone dar argumentos para relativizar el extendido relato de que el concepto de alienación perdió atención teórica por parte de la filosofía durante la década de los ochenta del siglo pasado y que recién a partir de los noventa ...
Sofía Ache
doaj
Indian Journal of Pathology and Microbiology, 2021 Background: Increased acetylcholinesterase (AChE) activity on frozen sections of rectal mucosal biopsies accurately diagnoses Hirschsprung disease (HD). But the quest for a biomarker in blood as a screening test prompts one to look for AChE in blood and ...
Neha Kuvelkar +6 more
doaj +1 more source
PharmaceuticsThe topical use of sunscreens is recommended for avoiding the damaging effects of UV radiation. However, improvements are still needed in the existing products to enhance their photoprotection effectiveness and safety. This involves minimizing the use of
Margarete M. de Araújo +8 more
doaj +1 more source
Acetylcholinesterase involvement in apoptosis
Frontiers in Molecular Neuroscience, 2012 To date, more than 40 different types of cells from primary cultures or cell lines have shown AChE expression during apoptosis and after the induction apoptosis by different stimuli. It has been well-established that increased AChE expression or activity
Xue-Jun eZhang, David S. eGreenberg
doaj +1 more source