Results 11 to 20 of about 64,209 (243)

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

open access: yesHepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman   +4 more
wiley   +1 more source

Towards a Unity of the Human Behavioral Sciences [PDF]

open access: yes, 2006
Despite their distinct objects of study, the human behavioral sciences all include models of individual human behavior. Unity in the behavioral sciences requires that there be a common underlying model of individual human behavior, specialized and ...
Gintis, Herbert
core   +6 more sources

A High‐Density Raman Photometry for Tracking and Quantifying of AchE Activity in The Brain of Freely Moving Animals with Network

open access: yesAdvanced Science, 2023
A high‐density Raman photometry based on a dual‐recognition strategy is created for accurately quantifying acetylcholinesterase (AchE) activity in 24 brain regions of free‐moving animals with network.
Zhonghui Zhang   +7 more
doaj   +1 more source

A INFLUÊNCIA DAS CRENÇAS NO APRENDIZADO DE LÍNGUA INGLESA: UM ESTUDO COMPARATIVO ENTRE ESTUDANTES BRASILEIROS E PORTUGUESES

open access: yesCompetência, 2015
Este artigo é um recorte da dissertação de mestrado da autora que abarca, entre outras temáticas, as crenças em relação ao aprendizado de língua inglesa, uma pauta que vem sendo discutida no campo da linguística aplicada nas últimas décadas ...
Débora Ache Borsatti
doaj   +1 more source

Interacting with α7 nAChR is a new mechanism for AChE to enhance the inflammatory response in macrophages

open access: yesActa Pharmaceutica Sinica B, 2020
Acetylcholine (ACh) regulates inflammation via α7 nicotinic acetylcholine receptor (α7 nAChR). Acetylcholinesterase (AChE), an enzyme hydrolyzing ACh, is expressed in immune cells suggesting non-classical function in inflammatory responses.
Etta Y.L. Liu   +8 more
doaj   +1 more source

N-acetylcholinesterase-induced apoptosis in Alzheimer's disease. [PDF]

open access: yesPLoS ONE, 2008
BackgroundAlzheimer's disease (AD) involves loss of cholinergic neurons and Tau protein hyper-phosphorylation. Here, we report that overexpression of an N-terminally extended "synaptic" acetylcholinesterase variant, N-AChE-S is causally involved in both ...
Debra Toiber   +5 more
doaj   +1 more source

A Computational Model of a Descending Mechanosensory Pathway Involved in Active Tactile Sensing. [PDF]

open access: yesPLoS Computational Biology, 2015
Many animals, including humans, rely on active tactile sensing to explore the environment and negotiate obstacles, especially in the dark. Here, we model a descending neural pathway that mediates short-latency proprioceptive information from a tactile ...
Jan M Ache, Volker Dürr
doaj   +1 more source

Ephemeral Work Group Formation of Jenu Kuruba Honey Collectors and Late 19th Century Coloado Silver Prospectors [PDF]

open access: yes, 2014
Humans frequently form short-lived cooperative groups to accomplish subsistence and economic tasks. We explore the ecological and cultural factors behind ephemeral work-group formation in two disparate cultural contexts: groups foraging for wild honey in
Demps, Kathryn   +1 more
core   +4 more sources

A Novel Acetylcholine Nanosensor for Single Vesicle Storage and Sub‐Quantal Exocytosis in Living Neurons and Organoids

open access: yesAngewandte Chemie, EarlyView.
Schematic representation of M@E@CF nanosensors for detecting vesicular storage and release in cholinergic neurons and brain organoids. (A) Nano‐tip microelectrodes modification via molds fabricated through 3D printing. (B) the reaction mechanism for acetylcholine detection at the electrode interface.
Wanying Zhu   +11 more
wiley   +2 more sources

PE - 114 Potencial menor impacto na pegada de carbono com o uso disseminado do dispositivo Aerocaps® (DPI) na categoria formoterol+budesonida: uma análise comparativa Brasil-EUA

open access: yesJornal de Assistência Farmacêutica e Farmacoeconomia
Introdução: O impacto ambiental dos inaladores pressurizados dosimetrados (pMDIs), amplamente usados no tratamento de doenças respiratórias, tem gerado crescente preocupação em saúde pública e ambiental.
Rodrigo Torres Scabello   +6 more
doaj   +1 more source

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