Results 1 to 10 of about 176,476 (335)

Circumdatin D Exerts Neuroprotective Effects by Attenuating LPS-Induced Pro-Inflammatory Responses and Downregulating Acetylcholinesterase Activity In Vitro and In Vivo

Frontiers in Pharmacology, 2020
Alzheimer's disease (AD) is a prevalent neurodegenerative disorder with multifactorial causes, of which systemic inflammation may play a key role to promote neurodegeneration, and acetylcholinesterase (AChE) is a target protein to induce cholinergic ...
Chanjuan Zhang, Likun Hu, Dong Liu, Jian Huang, Wenhan Lin   +4 more
doaj   +1 more source

Human Erythrocyte Acetylcholinesterase in Health and Disease

Molecules, 2017
The biochemical properties of erythrocyte or human red blood cell (RBC) membrane acetylcholinesterase (AChE) and its applications on laboratory class and on research are reviewed. Evidence of the biochemical and the pathophysiological properties like the
C. Saldanha
semanticscholar   +1 more source

ANTIBODIES TO ACETYLCHOLINESTERASE [PDF]

Proceedings of the National Academy of Sciences, 1969
A rabbit antiserum against commercially available Electrophorus electricus acetylcholinesterase has been prepared. Five precipitation bands were distinguished by immunoelectrophoresis, but only three of these contained demonstrable enzyme activity.
openaire   +2 more sources

Novel Bisquaternary Oximes—Reactivation of Acetylcholinesterase and Butyrylcholinesterase Inhibited by Paraoxon

Molecules, 2009
Four novel bisquaternary aldoxime cholinesterase reactivators differing in their chemical structure were prepared. Afterwards, their biological activity was evaluated for their ability to reactivate acetylcholinesterase (AChE; EC 3.1.1.7) and ...
Daniel Jun, Jana Zdarova Karasova, Miroslav Pohanka, Martina Hrabinova, Kamil Musilek, Martin Paar, Vladimir Cirkva, Jiri Palecek, Kamil Kuca, Lucie Musilova   +9 more
doaj   +1 more source

Isolation of Three Lycorine Type Alkaloids from Rhodolirium speciosum (Herb.) Ravenna Using pH-Zone-Refinement Centrifugal Partition Chromatography and Their Acetylcholinesterase Inhibitory Activities

Metabolites, 2020
Preparative separation of three lycorine type alkaloids from Rhodolirum speciosum (Amaryllidaceae) was successfully carried out using pH-zone-refinement centrifugal partition chromatography (CPC) using the solvent system methyl-tert-butyl ether ...
Diana Isabel Correa, Edgar Pastene-Navarrete, Luis Bustamante, Marcelo Baeza, Julio Alarcón-Enos   +4 more
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Amperometric acetylcholinesterase biosensor for physostigmine determination

Учёные записки Казанского университета: Серия Естественные науки, 2018
A biosensor based on acetylcholinesterase immobilized by carbodiimide binding on glassy carbon electrode modified with carbon black and Co(II) phthalocyanine has been developed.
R.R. Davletshina, A.N. Ivanov, G.A. Evtugyn   +2 more
doaj  

Acetylcholinesterase is not a generic marker of extracellular vesicles

Journal of Extracellular Vesicles, 2019
Acetylcholinesterase (AChE) activity is found in abundance in reticulocytes and neurons and was developed as a marker of reticulocyte EVs in the 1970s.
Zhaohao Liao, Lorena Martin Jaular, Estelle Soueidi, Mabel Jouve, Dillon C. Muth, Tine H. Schøyen, Tessa Seale, Norman J. Haughey, Matias Ostrowski, Clotilde Théry, Kenneth W. Witwer   +10 more
doaj   +1 more source

Rhodolirium andicola: a new renewable source of alkaloids with acetylcholinesterase inhibitory activity, a study from nature to molecular docking

, 2018
Acetylcholinesterase is an important target for control of neurodegenerative diseases causing cholinergic signaling deficit. Traditionally, galanthamine has been used as an Amaryllidaceae-derived acetylcholinesterase inhibitor, although new ...
Felipe Moraga-Nicolás, C. Jara, R. Godoy, Patricio Iturriaga-Vásquez, H. Venthur, A. Quiroz, J. Becerra, A. Mutis, E. Hormazábal   +8 more
semanticscholar   +1 more source

Acetylcholine Regulates Pulmonary Pathology During Viral Infection and Recovery

ImmunoTargets and Therapy, 2020
Alexander P Horkowitz,1,2 Ashley V Schwartz,3 Carlos A Alvarez,1,2 Edgar B Herrera,1 Marilyn L Thoman,1 Dale A Chatfield,4 Kent G Osborn,5 Ralph Feuer,2 Uduak Z George,3 Joy A Phillips1 1Donald P.
Horkowitz AP, Schwartz AV, Alvarez CA, Herrera EB, Thoman ML, Chatfield DA, Osborn KG, Feuer R, George UZ, Phillips JA   +9 more
doaj  

Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme.

Neuron, 1996
Acetylcholinesterase (AChE), an important component of cholinergic synapses, colocalizes with amyloid-beta peptide (A beta) deposits of Alzheimer's brain.
N. Inestrosa, A. Álvarez, C. A. Pérez, R. Moreno, M. Vicente, C. Linker, O. Casanueva, C. Soto, J. Garrido   +8 more
semanticscholar   +1 more source