Results 31 to 40 of about 85,087 (299)

Serum cholinesterases are differentially regulated in normal and dystrophin-deficient mutant mice

Frontiers in Molecular Neuroscience, 2012
The cholinesterases, acetylcholinesterase and butyrylcholinesterase (pseudocholinesterase), are abundant in the nervous system and in other tissues. The role of acetylcholinesterase in terminating transmitter action in the peripheral and central nervous ...
Andrea R. Durrant, Liliya eTamayev, Lili eAnglister   +2 more
doaj   +1 more source

The Effect of Parathion on Red Blood Cell Acetylcholinesterase in the Wistar Rat

Journal of Toxicology, 2016
Organophosphorus (OP) pesticide poisoning is a significant problem worldwide. Research into new antidotes for these acetylcholinesterase inhibitors, and even optimal doses for current therapies, is hindered by a lack of standardized animal models.
Naofumi Bunya, Keigo Sawamoto, Hanif Benoit, Steven B. Bird   +3 more
doaj   +1 more source

Eosinophil-mediated cholinergic nerve remodeling [PDF]

, 2006
Eosinophils are observed to localize to cholinergic nerves in a variety of inflammatory conditions such as asthma, rhinitis, eosinophilic gastroenteritis, and inflammatory bowel disease, where they are also responsible for the induction of cell ...
McLean, W.G., Anthony G. Fenech, Madziar, B., Madziar, Beata, Durcan, Niamh, Gleich, G.J., Walsh, M., Fenech, Anthony G., McLean, Graham W., Jan Blusztajn, Gerard J. Gleich, Gleich, Gerard J., Niamh Durcan, Hall, Ian P., Beata Madziar, Walsh, Marie-Therese, Hall, I.P., Ian P. Hall, Durcan, N., Costello, Richard W., Richard W. Costello, Marie-Therese Walsh, McGarvey, Lorcan, Costello, R.W., Fenech, A.G., W. Graham McLean, Lorcan McGarvey, Blusztain, J., Blusztajn, Jan   +28 more
core   +1 more source

Acetylcholinesterase: The “Hub” for Neurodegenerative Diseases and Chemical Weapons Convention

Biomolecules, 2020
This article describes acetylcholinesterase (AChE), an enzyme involved in parasympathetic neurotransmission, its activity, and how its inhibition can be pharmacologically useful for treating dementia, caused by Alzheimer’s disease, or as a warfare ...
Samir F. de A. Cavalcante, Alessandro B. C. Simas, Marcos C. Barcellos, Victor G. M. de Oliveira, Roberto B. Sousa, Paulo A. de M. Cabral, Kamil Kuča, Tanos C. C. França   +7 more
doaj   +1 more source

Insecticidal Terpenes From the Essential Oils of Artemisia nakaii and Their Inhibitory Effects on Acetylcholinesterase

Frontiers in Plant Science, 2021
Essential oils (EOs) are often the source of insecticidal substances of high efficiency and low toxicity. From gas chromatograph-mass spectrometer, column chromatography, and nuclear magnetic resonance spectra analyses, twenty terpenes were identified ...
Jiayi Liu, Juan Hua, Juan Hua, Bo Qu, Bo Qu, Xuanyue Guo, Yangyang Wang, Meini Shao, Shihong Luo, Shihong Luo   +9 more
doaj   +1 more source

Three hydrolases and a transferase: comparative analysis of active-site dynamics via the BioSimGrid database [PDF]

, 2007
Comparative molecular dynamics (MD) simulations enable us to explore the conformational dynamics of the active sites of distantly related enzymes.
Baaden, Marc, Muan Hong Ngd, Essex, Jonathan, Sansom, MS, Sansom, Mark, Murdock, S, Cox, K, Cox, Katherine, Tai, K, Ng, Muan Hong, Tai, Kaihsu, Jonathan W. Essexc, Steven Johnstonc, Bing Wua, Marc Baadenb, Essex, Jonathan W, Baaden, M, Essex, JW, Essex, Jonathan W., Sansom, Mark S.P., Murdock, Stuart, Wu, Bing, Stuart Murdockc, Johnston, Steven, Fangohr, Hans, Wu, B, Kaihsu Taia, Richard Boardmanc, Ng, MH, Boardman, R, Fangohr, H, Mark S. P. Sansoma, Katherine Coxa, Sansom, Mark S. P., Johnston, S, Hans Fangohrd, Boardman, Richard   +36 more
core   +1 more source

ACETYLCHOLINESTERASE, TYROSINASE AND PEROXIREDOXIN ENZYME INHIBITORY ACTIVITY STUDIES OF SYNTHESISED OXADIAZOLES AND THIADIAZOLES FROM SCHIFF BASES [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University
With the increasing prevalence of neurodegenerative diseases (NDDs) and the limited effectiveness of existing treatments, there is a pressing need to discover new therapeutic leads that can interact with multiple targets implicated in NDD pathogenesis. A
Sindhu J, JAINEY JAMES, keerthan shettigar, Zakiya C   +3 more
doaj   +1 more source

Acetylcholinesterase-Capped Mesoporous Silica Nanoparticles That Open in the Presence of Diisopropylfluorophosphate (a Sarin or Soman Simulant)

, 2016
Mesoporous silica nanoparticles loaded with rhodamine B and capped with acetylcholinesterase are able to be selectively opened and deliver their cargo in the presence of nerve agent simulant diisopropyl fluorophosphate (DFP)
Ramón Martínez-Máñez (1495048), Pablo Gaviña (1669132), Lluís Pascual (3224601), Sameh El Sayed (654273), Ana M. Costero (654278), Félix Sancenón (1495057), Salvador Gil (654280)   +6 more
core   +1 more source

New Steroidal Saponins from Rhizomes of Trillium govanianum: Gram Scale Isolation and Acetylcholinesterase Inhibitory Activity Evaluation [PDF]

, 2022
Three previously unknown steroidal saponins named as govanoside C-E (1-3) along with four known compounds, govanoside B (4), protodioscin (5), 20β-hydroxyecdysone (6), and polypodine B (7) have been isolated from the rhizomes of Trillium govanianum Wall.
Anmol, -, Patil Shivprasad , Suresh, Prithvi Pal, Singh, Upendra, Sharma   +3 more
core   +2 more sources

Organophosphorus insecticides: Toxic effects and bioanalytical tests for evaluating toxicity during degradation processes [PDF]

Hemijska Industrija, 2013
Organophosphorus insecticides have been the most applied group of insecticides for the last two decades. Their main toxic effects are related to irreversible inactivation of acetylcholinesterase (AChE).
Čolović Mirjana B., Krstić Danijela Z., Vasić Vesna M., Bondžić Aleksandra M., Ušćumlić Gordana S., Petrović Slobodan D.   +5 more
doaj   +1 more source