Results 31 to 40 of about 176,476 (335)

Protection of insect neurons by erythropoietin/CRLF3-mediated regulation of pro-apoptotic acetylcholinesterase

Scientific Reports, 2022
Cytokine receptor-like factor 3 (CRLF3) is a conserved but largely uncharacterized orphan cytokine receptor of eumetazoan animals. CRLF3-mediated neuroprotection in insects can be stimulated with human erythropoietin.
Debbra Y. Knorr, Kristin Schneider, Luca Büschgens, Jan Förster, Nadine S. Georges, Bart R. H. Geurten, Ralf Heinrich   +6 more
doaj   +1 more source

Growth, photosynthetic pigments, phenolic content and biological activities of Foeniculum vulgare Mill., Anethum graveolens L. and Pimpinella anisum L. (Apiaceae) in response to zinc [PDF]

, 2017
The effect of zinc (Zn) on phenols, antioxidant activities (free radicals' scavenging activities, inhibition of lipid peroxidation, chelating activity and reducing power), and enzyme inhibition activities of acetylcholinesterase, lipoxygenase and ...
Ben Kaab, Leila Bettaieb, Carlier, Jorge, Clara Costa, Maria, EL-GEUNDOUZ, Soukaina, MAJDOUB, Nesrine, Miguel, Maria Graca, Rezgui, Marwa   +6 more
core   +1 more source

Biological activities of ethanolic extracts from deep-sea antarctic marine sponges [PDF]

, 2013
We report on the screening of ethanolic extracts from 33 deep-sea Antarctic marine sponges for different biological activities. We monitored hemolysis, inhibition of acetylcholinesterase, cytotoxicity towards normal and transformed cells and growth ...
Ambrožič Avguštin, Jerneja, Batista, Urška, Janussen, Dorte, Kauferstein, Silke, Kosmina, Rok, Mebs, Dietrich, Sepčić, Kristina, Strugar, Gašper, Turk, Tom, Čivović, Sandra   +9 more
core   +3 more sources

Biological activities and chemical composition of methanolic extracts of selected Autochthonous microalgae strains from the Red Sea [PDF]

, 2015
Four lipid-rich microalgal species from the Red Sea belonging to three different genera (Nannochloris, Picochlorum and Desmochloris), previously isolated as novel biodiesel feedstocks, were bioprospected for high-value, bioactive molecules.
Carolina Bruno De Sousa, Florêncio Nogueira, Fouzi Mouffouk, Hugo Pereira, José Manuel, João Varela, Khalid M. Abu-salah, Luísa Barreira, Luísa Custódio, Maria João Rodrigues, Marta Oliveira, Nuno Da Rosa Neng, Radhouan Ben-hamadou, Salman A. Alrokayan, The Red Sea   +14 more
core   +4 more sources

AChE-activity in critically ill patients with suspected septic encephalopathy: a prospective, single-centre study

BMC Anesthesiology, 2020
Background Up to 70% of septic patients develop a diffuse brain dysfunction named “septic associated encephalopathy” which is often solely based on clinical impressions.
Benedikt Zujalovic, Benjamin Mayer, Sebastian Hafner, Florian Balling, Eberhard Barth   +4 more
doaj   +1 more source

Biological activities of aqueous and organic extracts from tropical marine sponges [PDF]

, 2010
We report on screening tests of 66 extracts obtained from 35 marine sponge species from the Caribbean Sea (Curaçao) and from eight species from the Great Barrier Reef (Lizard Island). Extracts were prepared in aqueous and organic solvents and were tested
Sepčić, Kristina, Kauferstein, Silke, Mebs, Dietrich, Turk, Tom   +3 more
core   +2 more sources

A novel process driving Alzheimer's disease validated in a mouse model: Therapeutic potential

Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2022
Introduction The neuronal mechanism driving Alzheimer's disease (AD) is incompletely understood. Methods Immunohistochemistry, pharmacology, biochemistry, and behavioral testing are employed in two pathological contexts—AD and a transgenic mouse model—to
Susan A. Greenfield, Gregory M. Cole, Clive W. Coen, Sally Frautschy, Ram P. Singh, Marisa Mekkittikul, Sara Garcia‐Ratés, Paul Morrill, Owen Hollings, Matt Passmore, Sibah Hasan, Nikisha Carty, Silvia Bison, Laura Piccoli, Renzo Carletti, Stephano Tacconi, Anna Chalidou, Matthew Pedercini, Tim Kroecher, Hubert Astner, Philip A. Gerrard   +20 more
doaj   +1 more source

Biochemical and molecular responses of the freshwater snail Pila sp. to environmental pollutants, abiotic, and biotic stressors

Frontiers in Environmental Science, 2022
The semi-sessile, ectothermic, amphibious mollusc Pila globosa receives less attention for studying its environmental aspects. Its ecological role, ecotoxic and physiological responses to environmental factors including pollution and during dormant ...
Falguni Panda, Falguni Panda, Samar Gourav Pati, Samar Gourav Pati, Kajari Das, Luna Samanta, Dipak Kumar Sahoo, Biswaranjan Paital   +7 more
doaj   +1 more source

Merged Tacrine-Based, Multitarget-Directed Acetylcholinesterase Inhibitors 2015–Present: Synthesis and Biological Activity

International Journal of Molecular Sciences, 2020
Acetylcholinesterase is an important biochemical enzyme in that it controls acetylcholine-mediated neuronal transmission in the central nervous system, contains a unique structure with two binding sites connected by a gorge region, and it has ...
Todd J. Eckroat, Danielle L Manross, Seth C Cowan   +2 more
semanticscholar   +1 more source

Dysregulated homeostasis of acetylcholine levels in immune cells of RR-multiple sclerosis patients [PDF]

, 2016
Multiple sclerosis (MS) is characterized by pro-inflammatory cytokine production. Acetylcholine (ACh) contributes to the modulation of central and peripheral inflammation.
Biagioni, Stefano, Costantini, Erica, DI BARI, Maria, Di Nicola, Marta, D’Angelo, Chiara, Galizia, Sabrina, Gasperini, Claudio, Orlando, Viviana, Porfilio, Italo, Reale, Marcella, Ruggieri, Serena, Tata, Ada Maria   +11 more
core   +2 more sources