Results 11 to 20 of about 176,476 (335)
International Journal of Molecular Sciences, 2021 Acetylcholinesterase (AChE) plays an important role in the pathogenesis of neurodegenerative diseases by influencing the inflammatory response, apoptosis, oxidative stress and aggregation of pathological proteins. There is a search for new compounds that
Łucja Justyna Walczak-Nowicka +1 more
exaly +2 more sources
Molecular Genetic Studies on Honeybees in Response to Some Environmental Stresses [PDF]
Arab Universities Journal of Agricultural Sciences, 2023 The honeybee, Apis mellifera, is a widespread pollinator insect. Colony collapse disorder (CCD) has recently caused a significant decline in honeybee numbers worldwide.
Rehab Mohamed +4 more
doaj +1 more source
Cardiovascular Complications of Acetylcholinesterase Inhibitors in Patients with Alzheimer’s Disease: A Narrative Review [PDF]
Annals of Geriatric Medicine and Research, 2021 While acetylcholinesterase inhibitors are used to treat a wide range of patients with Alzheimer’s disease, acetylcholinesterase inhibitor use has also been associated with a variety of cardiovascular complications, including bradycardia and syncope ...
Sara Young, Enoch Chung, Michael A. Chen
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Mechanisms of Organophosphate Toxicity and the Role of Acetylcholinesterase Inhibition
Toxics, 2023 Organophosphorus compounds (OPs) have applications in agriculture (e.g., pesticides), industry (e.g., flame retardants), and chemical warfare (nerve agents). In high doses or chronic exposure, they can be toxic or lethal.
V. Aroniadou-Anderjaska +4 more
semanticscholar +1 more source
Molecules, 2023 Alzheimer’s disease (AD), a neurodegenerative brain disorder that affects millions of people worldwide, is characterized by memory loss and cognitive decline.
Stergiani-Chrysovalanti Peitzika +1 more
semanticscholar +1 more source
Readthrough acetylcholinesterase is increased in human liver cirrhosis. [PDF]
PLoS ONE, 2012 BACKGROUND & AIMS: There have been many studies on plasma butyrylcholinesterase in liver dysfunction. However, no data is available about acetylcholinesterase in human cirrhosis, although profound changes have been described in cirrhotic rat models ...
María-Salud García-Ayllón +4 more
doaj +1 more source
The State of The Art on Acetylcholinesterase Inhibitors in the Treatment of Alzheimer’s Disease
Journal of Central Nervous System Disease, 2021 Alzheimer’s disease (AD) is a chronic disabling disease that affects the central nervous system. The main consequences of AD include the decline of cognitive functions and language disorders.
I. Vecchio +4 more
semanticscholar +1 more source
Molecules, 2021 Isoquinoline alkaloids may have a wide range of pharmacological activities. Some of them have acetylcholinesterase activity inhibition. Nowadays, neurodegenerative disorders such as Alzheimer’s disease have become a serious public health problem ...
Tomasz Tuzimski, Anna Petruczynik
doaj +1 more source
Bioinformatics and Biology Insights, 2022 The inhibition of acetylcholinesterase plays a vital role in the treatment of Alzheimer disease. This study aimed to explore the acetylcholinesterase inhibition potential of Phyllanthus amarus and its phytoconstituents through an in vitro and in silico ...
Kolade O Faloye +10 more
doaj +1 more source
Efficacy of acetylcholinesterase inhibitors in Alzheimer's disease.
Neuropharmacology, 2020 Alzheimer's disease (AD), the most common cause of adult-onset dementia is characterized by a progressive decline of cognitive functions accompanied by behavioral manifestations.
G. Marucci +5 more
semanticscholar +1 more source