Results 1 to 10 of about 21,484 (162)

Cholinesterase inhibitors and hospitalization for bradycardia: a population-based study. [PDF]

open access: yesPLoS Medicine, 2009
BACKGROUND: Cholinesterase inhibitors are commonly used to treat dementia. These drugs enhance the effects of acetylcholine, and reports suggest they may precipitate bradycardia in some patients.
Laura Y Park-Wyllie   +5 more
doaj   +3 more sources

Cholinesterase Inhibitors from Plants and Their Potential in Alzheimer’s Treatment: Systematic Review [PDF]

open access: yesBrain Sciences
Introduction: Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by memory loss and cognitive decline, primarily due to dysfunction of acetylcholine caused by acetylcholinesterase and butyrylcholinesterase.
Maryam N. ALNasser   +3 more
doaj   +2 more sources

Adverse Effects of Cholinesterase Inhibitors in Dementia, According to the Pharmacovigilance Databases of the United-States and Canada.

open access: yesPLoS ONE, 2015
This survey analyzes two national pharmacovigilance databases in order to determine the major adverse reactions observed with the use of cholinesterase inhibitors in dementia.
Thibault B Ali   +4 more
doaj   +3 more sources

Potential revival of cholinesterase inhibitors as drugs in veterinary medicine

open access: yesFrontiers in Veterinary Science, 2023
The cholinergic system is involved in the regulation of all organ systems and has acetylcholine (ACh) as almost its only neurotransmitter. Any substance is called cholinergic if it can alter the action of acetylcholine. Cholinesterases (ChEs) are enzymes
Neža Žnidaršič   +3 more
doaj   +1 more source

Plant Terpenoids as the Promising Source of Cholinesterase Inhibitors for Anti-AD Therapy

open access: yesBiology, 2022
Plant-derived terpenes are the prolific source of modern drugs such as taxol, chloroquine and artemisinin, which are widely used to treat cancer and malaria infections.
Shereen Lai Shi Min   +5 more
doaj   +1 more source

Can Marine Products Improve Alzheimer’s Disease [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 2020
Alzheimer's disease is an irreversible chronic neurodegenerative disease which is the most common cause of dementia among older adults. According to amyloid hypothesis, cholin neurotransmitters have important roles in CNS memory function, therefore ...
Hamid-Reza Adhami, Paria Sharafi
doaj   +1 more source

Association of cognitive enhancers and incident seizure risk in dementia: a population-based study

open access: yesBMC Geriatrics, 2022
Background Although individuals with dementia have a high risk of developing seizures, whether seizures are associated with cholinesterase inhibitors, which are commonly prescribed to treat individuals with dementia, remains unknown.
Junghee Ha   +5 more
doaj   +1 more source

A Study on Beta-Glucuronidase Enzyme as a Probable Biomarker in Cases of Acute Poisoning by Cholinesterase Enzyme Inhibitor Insecticides [PDF]

open access: yesAin Shams Journal of Forensic Medicine and Clinical Toxicology, 2014
Acute poisoning by cholinesterase enzyme inhibitors insecticide continues to be a detrimental problem and a potential cause of mortality especially in developing countries. Early intervention in such cases is proven to be helpful.
Shawky El-Naggar   +3 more
doaj   +1 more source

Cholinesterase inhibitors for delirium [PDF]

open access: yesCochrane Database of Systematic Reviews, 2005
Delirium is now the preferred term to describe acute confusional states. It is experienced by 10 to 30% of all hospital inpatients. Delirium is potentially reversible and is related to several adverse outcomes, including increased hospital length of stay, poor functional status, persistent cognitive impairment, need for institutional care and probably ...
R, Overshott, S, Karim, A, Burns
openaire   +2 more sources

Bioactivity-Guided Separation of Anti-Cholinesterase Alkaloids from Uncaria rhynchophlly (Miq.) Miq. Ex Havil Based on HSCCC Coupled with Molecular Docking

open access: yesMolecules, 2022
As an important source of cholinesterase inhibitors, alkaloids in natural products have high potential value in terms of exerting pharmacological activities.
Pengfei Yu   +8 more
doaj   +1 more source

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