Results 11 to 20 of about 22,708 (195)
Cholinesterase inhibitors for delirium [PDF]
Delirium is now the preferred term to describe acute confusional states. It is experienced by 10 to 30% of all hospital inpatients. Delirium is potentially reversible and is related to several adverse outcomes, including increased hospital length of stay, poor functional status, persistent cognitive impairment, need for institutional care and probably ...
R, Overshott, S, Karim, A, Burns
openaire +2 more sources
As an important source of cholinesterase inhibitors, alkaloids in natural products have high potential value in terms of exerting pharmacological activities.
Pengfei Yu +8 more
doaj +1 more source
An examination of three prescribing cascades in a cohort of older adults with dementia
Background Prescribing cascades are a source of inappropriate prescribing for older adults with dementia. We aimed to study three prescribing cascades in older Nova Scotians with dementia using administrative databases.
Shanna C. Trenaman +3 more
doaj +1 more source
Benzene-1,3-diol derivatives as the inhibitors of butyrylcholinesterase: An emergent target of Alzheimer’s disease [PDF]
Molecular docking is a powerful and significant approach for the identification of lead molecules on the basis of virtual screening. With it a large number of compounds can be tested and based on the scoring function and ranking, the conclusion can be ...
Dongliang Yin +7 more
doaj +1 more source
Cholinesterase inhibitors have been the subject of many studies aimed at developing an effective treatment for various cognitive disorders. Therefore, studying cholinesterases and elucidating the mechanism of their interaction with ligands provide a ...
A.R. Mukhametgalieva +3 more
doaj +1 more source
The search for effective yet environmentally friendly strategies to prevent marine biofouling is hampered by the large taxonomic diversity amongst fouling organisms and a lack of well-defined conserved molecular targets.
Homayon John Arabshahi +7 more
doaj +1 more source
Non-Alkaloid Cholinesterase Inhibitory Compounds from Natural Sources
Alzheimer’s disease (AD) is a severe neurodegenerative disorder of different brain regions accompanied by distresses and affecting more than 25 million people in the world.
Alfred Ngenge Tamfu +4 more
doaj +1 more source
Understanding Alzheimer disease
Alzheimer disease (AD) is a neurodegenerative disorder with an uncertain pathogenesis. It is characterised by symptoms of memory impairment, executive dysfunction and visuospatial impairment.
M. Vally, F. Kathrada
doaj +1 more source
In our previous research, some screened 1,3-thiazole fragments were found to be potent by inhibiting LPS-induced TNF$\alpha $ and IL-8 release with IC50 values in the $\mu $M range without cytotoxic activity.
Modrić, Marina +7 more
doaj +1 more source
The acetylcholinesterase as indicative of intoxication for pesticide in farmers of conventional and organic cultivation [PDF]
In this sense the objective of assessing the levels of pesticide poisoning in rural farmers of San Sebastian and take AL, using acetylcholinesterase enzymes Erythrocyte and plasma as biological indicator of intoxication.
H. H. F. Alves +9 more
doaj +1 more source

