Results 1 to 10 of about 362,575 (339)
The Alzheimer variant of Lewy body disease: A pathologically confirmed case-control study [PDF]
, 2005 The objective of the study was to identify clinical features that distinguish patients with dementia with Lewy bodies (DLB), who were classified as Alzheimer's disease ( AD) patients, from patients with AD.
Busch, R. +7 more
core +3 more sources
Using the A/T/N Framework to Examine Driving in Preclinical Alzheimer’s Disease [PDF]
Geriatrics, 2018 The A/T/N classification system is the foundation of the 2018 NIA-AA Research Framework and is intended to guide the Alzheimer disease (AD) research agenda for the next 5–10 years.
Catherine M. Roe +9 more
doaj +4 more sources
Network: Computation in Neural Systems, 2011 Over the last three decades, advances in biochemical pathology and human genetics have illuminated one of the most enigmatic subjects in biomedicine--neurodegeneration. Eponymic diseases of the nervous system such as Alzheimer's, Parkinson's, and Huntington's diseases that were long characterized by mechanistic ignorance have yielded striking progress ...
Adam, Gazzaley, Scott A, Small
+11 more sources
BMJ Open, 2022 Objective Preventing Alzheimer’s dementia (AD) fundamentally equates to delaying onset. Thus, we quantified associations of modifiable, psychosocial risk factors to years of delayed onset of dementia.Design Two prospective cohorts (n=2860) with negative ...
Robert S Wilson +4 more
doaj +1 more source
Neurobiology of Disease, 2000 Use of valid diagnostic criteria is extremely important in the recognition of Alzheimer's disease (AD). Patients with mild to moderate Alzheimer's disease should be started on a cholinesterase inhibitor and possibly anti-inflammatory agents, antioxidants (vitamin E or selegiline), and estrogen replacement therapy (for postmenopausal women).
, Schachter, , Davis
+8 more sources
Brain Sciences, 2021 Objective: The aim of the current study was to estimate the discriminant potential and validity of the Digit Symbol Substitution Test (DSST) of the WAIS-R in the Greek elderly population meeting criteria for subjective cognitive decline (SCD), mild ...
Marianna Tsatali +8 more
doaj +1 more source
Plasma microRNAs as potential biomarkers in early Alzheimer disease expression
Scientific Reports, 2022 The microRNAs (miRNAs) are potential biomarkers for complex pathologies due to their involvement in the regulation of several pathways. Alzheimer Disease (AD) requires new biomarkers in minimally invasive samples that allow an early diagnosis. The aim of
Carmen Peña-Bautista +7 more
doaj +1 more source
Brain Sciences, 2022 Background: It can be easily inferred that dementia caregivers were severely affected by the general home confinement, or ‘lockdown’, due to their caregiving roles.
Evdokia Nikolaidou +6 more
doaj +1 more source
Biosensors, 2021 Presenilin (PS)/γ-secretase is an aspartyl protease that processes a wide range of transmembrane proteins such as the amyloid precursor protein (APP) and Notch1, playing essential roles in normal biological events and diseases.
Mei C. Q. Houser +5 more
doaj +1 more source
GPS driving: a digital biomarker for preclinical Alzheimer disease
Alzheimer’s Research & Therapy, 2021 Background Alzheimer disease (AD) is the most common cause of dementia. Preclinical AD is the period during which early AD brain changes are present but cognitive symptoms have not yet manifest.
Sayeh Bayat +6 more
doaj +1 more source