Results 1 to 10 of about 238,696 (131)
Nature Reviews Disease Primers, 2021 Alzheimer disease (AD) is biologically defined by the presence of β-amyloid-containing plaques and tau-containing neurofibrillary tangles. AD is a genetic and sporadic neurodegenerative disease that causes an amnestic cognitive impairment in its prototypical presentation and non-amnestic cognitive impairment in its less common variants.
David S. Knopman +7 more
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Network: Computation in Neural Systems, 2011 Over the last three decades, advances in biochemical pathology and human genetics have illuminated one of the most enigmatic subjects in biomedicine--neurodegeneration. Eponymic diseases of the nervous system such as Alzheimer's, Parkinson's, and Huntington's diseases that were long characterized by mechanistic ignorance have yielded striking progress ...
Adam, Gazzaley, Scott A, Small
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Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2023 Introduction The study examined Black and White prospective participants’ views of barriers to and facilitators of participation in Alzheimer's disease (AD) biomarker research.
Johanne Eliacin +12 more
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iScience, 2021 Summary: It has been suggested that aberrant activation of glycogen synthase kinase-3-beta (GSK-3β) can trigger abnormal tau hyperphosphorylation and aggregation, which ultimately leads to neuronal/synaptic damage and impaired cognition in Alzheimer ...
Ana Claudia Amaral +15 more
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Journal of Neurology, Neurosurgery & Psychiatry, 2000 Use of valid diagnostic criteria is extremely important in the recognition of Alzheimer's disease (AD). Patients with mild to moderate Alzheimer's disease should be started on a cholinesterase inhibitor and possibly anti-inflammatory agents, antioxidants (vitamin E or selegiline), and estrogen replacement therapy (for postmenopausal women).
, Schachter, , Davis
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Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2023 Introduction Acculturation‐related characteristics, that is, factors directly connected to culture and familial relationships, are associated with engaged research participation within Latino communities.
Melissa Lamar +6 more
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Health Science Reports, 2022 Background and Aims Alzheimer's disease (AD) is the main cause of dementia and over the 55 million people live with dementia worldwide. We aimed to establish the first database called the Iranian Alzheimer's Disease Registry to create a powerful source ...
Javad Fahanik‐Babaei +19 more
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Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2018 Alzheimer's disease (AD) is a serious medical and social problem of our time, while remaining the most common cause of dementia in the elderly. The leading symptom in the clinical picture of the disease is a progressive loss of memory with further development of behavioral disorders.
O A, Kicherova, L I, Reikhert
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Neuropsychiatric symptoms in Brazilians with mild cognitive impairment and dementia
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2021 Introduction Knowledge is limited about behavioral and psychological symptoms of mild cognitive impairment (MCI) and dementia in racial and ethnic minorities.
Robert S. Wilson +6 more
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Relationship of fasting glucose and longitudinal Alzheimer's disease imaging markers
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2022 Introduction Fasting glucose increases with age and is linked to modifiable Alzheimer's disease risk factors such as cardiovascular disease and Type 2 diabetes (T2D).
Robyn A. Honea +9 more
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