Results 11 to 20 of about 340,510 (279)

A data-driven examination of apathy and depressive symptoms in dementia with independent replication [PDF]

, 2023
Data used in preparation of this article were obtained from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database (adni.loni.usc.edu). As such, the investigators within the ADNI contributed to the design and implementation of ADNI and/or ...
Schuff, N, Stern, Y, Reinwald, LT, Carroll, M, Ward, C, Ballard, C, Jagust, W, Mathis, C, Schneider, LS, Teodoro, L, Meyer, JV, Gessert, D, Harvey, D, Dolen, S, Mintun, MA, Weiner, M, Carter, R, Leon, S, Ances, B, Householder, E, Rountree, S, Gunter, J, Brewer, J, Toga, AW, Schneider, S, Landau, S, Creese, B, Bell, KL, Aisen, P, Shaw, LM, Senjem, M, Jack, CR, Melendez-Torres, GJ, Sather, T, Nho, K, Shen, L, Dang, M, Borowski, B, DeCArli, C, Molchan, S, Beckett, L, Frank, R, Liu, E, Foroud, TM, Cairns, NJ, Korecka, M, Oliver, A, Lord, JL, Koeppe, RA, Knopman, D, Fleisher, A, Walter, S, Vasconcelos Da Silva, M, Fox, N, Albers, CS, Beccera, M, Vemuri, P, Lee, V, Lind, B, Green, RC, Figurski, M, Kim, S, Snyder, PJ, Johnson, K, Heidebrink, JL, Pawluczyk, S, Thomas, RG, Foster, N, Jones, D, Honig, LS, Petersen, R, Bernstein, M, Chowdhury, M, Spann, BM, Kaye, J, Marson, D, Montine, T, Kantarci, K, Trojanowki, JQ, Kachaturian, Z, Testad, I, Reiman, EM, Chen, K, Mason, SS, Crawford, K, Van der Swag, H, Donohue, M, Jiminez, G, Morris, J, Doody, RS, Potkin, S, Kelley, F, Ismail, Z, Saykin, AJ, Quinn, J, Thompson, P, Neu, S   +96 more
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Identification of gene pathways implicated in Alzheimer's disease using longitudinal imaging phenotypes with sparse regression. [PDF]

, 2012
We present a new method for the detection of gene pathways associated with a multivariate quantitative trait, and use it to identify causal pathways associated with an imaging endophenotype characteristic of longitudinal structural change in the brains ...
Alzheimer's Disease Neuroimaging Initiative, Silver, Matt, Montana, Giovanni, Thompson, Paul M, Janousova, Eva, Thompson, Paul M., Hua, Xue   +6 more
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Relation of neuropathology with cognitive decline among older persons without dementia

Frontiers in Aging Neuroscience, 2013
Objective: Although it is now widely accepted that dementia has a long preclinical phase during which neuropathology accumulates and cognition declines, little is known about the relation of neuropathology with the longitudinal rate of change in ...
Patricia eBoyle, Lei eYu, Robert eWilson, Julie eSchneider, David Alan Bennett   +4 more
doaj   +1 more source

ARIA in patients treated with lecanemab (BAN2401) in a phase 2 study in early Alzheimer's disease

Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2023
INTRODUCTION Lecanemab is a humanized immunoglobulin G1 (IgG1) monoclonal antibody that preferentially targets soluble aggregated Aβ species (protofibrils) with activity at amyloid plaques.
Lawrence S. Honig, Jerome Barakos, Shobha Dhadda, Michio Kanekiyo, Larisa Reyderman, Michael Irizarry, Lynn D. Kramer, Chad J. Swanson, Marwan Sabbagh   +8 more
doaj   +1 more source

Resting state cortical EEG rhythms in Alzheimer's disease: toward EEG markers for clinical applications: a review [PDF]

, 2012
The human brain contains an intricate network of about 100 billion neurons. Aging of the brain is characterized by a combination of synaptic pruning, loss of cortico-cortical connections, and neuronal apoptosis that provoke an age-dependent decline of ...
Lizio, Roberta, De Vico Fallani, Fabrizio, Fabrizio Vecchio, F. De Vico Fallani, Frisoni, Giovanni, Fabrizio De Vico Fallani, Giulio Verrienti, Giovanni Frisoni, Vecchio, Fabrizio, Rossini, Paolo M, G. Verrienti, P. M. Rossini, F. Vecchio, Verrienti, Giulio, Frisoni, Giovanni B., Paolo M. Rossini, Rossini, Paolo M., Babiloni, Claudio, Fde V. Fallani, Blinowska, Katarzyna, G. Frisoni, Rossini, Paolo Maria, Claudio Babiloni, K. Blinowska, Katarzyna Blinowska, Roberta Lizio   +25 more
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Risk Aversion is Associated with Decision Making among Community-Based Older Persons

Frontiers in Psychology, 2012
Background: Risk aversion is associated with many important decisions among younger and middle aged persons, but the association of risk aversion and decision making has not been well studied among older persons who face some of the most significant ...
Patricia eBoyle, Lei eYu, Aron eBuchman, David eBennett   +3 more
doaj   +1 more source

Differentiating among stages of cognitive impairment in aging: Version 3 of the Uniform Data Set (UDS) neuropsychological test battery and MoCA index scores

Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2020
Introduction Federally funded Alzheimer's Disease Centers in the United States have been using a standardized neuropsychological test battery as part of the National Alzheimer's Coordinating Center Uniform Data Set (UDS) since 2005. Version 3 (V3) of the
Hiroko H. Dodge, Felicia C. Goldstein, Nicole I Wakim, Tamar Gefen, Merilee Teylan, Kwun C.G. Chan, Walter A. Kukull, Lisa L. Barnes, Bruno Giordani, Timothy M. Hughes, Joel H. Kramer, David A. Loewenstein, Daniel C. Marson, Dan M. Mungas, Nora Mattek, Bonnie C. Sachs, David P. Salmon, Monica Willis‐Parker, Kathleen A. Welsh‐Bohmer, Katherine V. Wild, John C. Morris, Sandra Weintraub, National Alzheimer's Coordinating Center (NACC)   +22 more
doaj   +1 more source

Deep learning improves utility of tau PET in the study of Alzheimer's disease

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2021
Introduction Positron emission tomography (PET) imaging targeting neurofibrillary tau tangles is increasingly used in the study of Alzheimer's disease (AD), but its utility may be limited by conventional quantitative or qualitative evaluation techniques ...
James Zou, David Park, Aubrey Johnson, Xinyang Feng, Michelle Pardo, Jeanelle France, Zeljko Tomljanovic, Adam M. Brickman, Devangere P. Devanand, José A. Luchsinger, William C. Kreisl, Frank A. Provenzano, for the Alzheimer's Disease Neuroimaging Initiative   +12 more
doaj   +1 more source

Resting state cortical electroencephalographic rhythms in covert hepatic encephalopathy and Alzheimer's disease [PDF]

, 2013
Patients suffering from prodromal (i.e., amnestic mild cognitive impairment, aMCI) and overt Alzheimer's disease (AD) show abnormal cortical sources of resting state electroencephalographic (EEG) rhythms.
Nicola Marzano, Lizio, Roberta, Giovanni B. Frisoni, Serviddio, Gaetano, Vecchio F, Chini G, Piero Amodio, Frisoni GB, P. M. Rossini, Schiff S, Babiloni C, F. Vecchio, Frisoni, Giovanni B., Amodio P., Paolo M. Rossini, A. Soricelli, Serviddio G, G. B. Frisoni, C. Del Percio, Babiloni, Claudio, Chini, Giorgia, Del Percio C, Soricelli, Andrea, Marzano N, P. Amodio, Rossini, Paolo Maria, Lizio R, Roberta Lizio, Sami Schiff, Montagnese, Sara, S. Montagnese, S. Schiff, Fabrizio Vecchio, Rossini PM, Schiff, Sami, Soricelli A, Vecchio, Fabrizio, Marzano, Nicola, Del Percio, Claudio, Claudio Del Percio, G. Chini, Rossini, Paolo M., G. Serviddio, Andrea Soricelli, N. Marzano, Gaetano Serviddio, Sara Montagnese, Amodio, Piero, Claudio Babiloni, Giorgia Chini, Montagnese S   +50 more
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EEG UPPER/LOW ALPHA FREQUENCY POWER RATIO RELATES TO TEMPORO-PARIETAL BRAIN ATROPHY AND MEMORY PERFORMANCES IN MILD COGNITIVE IMPAIRMENT

Frontiers in Aging Neuroscience, 2013
Objective: temporo-parietal cortex thinning is associated to mild cognitive impairment (MCI) due to Alzheimer disease (AD). The increase of EEG upper/low alpha power ratio has been associated with AD-converter MCI subjects.
Davide Vito Moretti, donata epaternicò, Giuliano eBinetti, Orazio eZanetti, giovanni b Frisoni   +4 more
doaj   +1 more source