Results 21 to 30 of about 5,103,561 (270)

Preliminary report of Iranian Registry of Alzheimer's disease in Tehran province: A cross‐sectional study in Iran

Health Science Reports, 2022
Background and Aims Alzheimer's disease (AD) is the main cause of dementia and over the 55 million people live with dementia worldwide. We aimed to establish the first database called the Iranian Alzheimer's Disease Registry to create a powerful source ...
Javad Fahanik‐Babaei, Mohsen Sedighi, Soraya Mehrabi, Omid Pournik, Abbas Sheikh Taheri, Leila Kamalzadeh, Mahsa Zarei, Mehrdad Roghani, Fereshteh Golab, Mostafa Almasi, Afshin Etezadi, Siamak Afshin‐Majd, Seyed Kazem Malakouti, Majid Rajabi, Mehdi Moghaddasi, Gholamreza Hajati, Fatemeh Golmohammadi Khamne, Arzhang Jafari, Alireza Amanollahi, Tourandokht Baluchnejadmojarad   +19 more
doaj   +1 more source

Neuropsychiatric symptoms in Brazilians with mild cognitive impairment and dementia

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2021
Introduction Knowledge is limited about behavioral and psychological symptoms of mild cognitive impairment (MCI) and dementia in racial and ethnic minorities.
Robert S. Wilson, Ana W Capuano, Carolina Sampaio, Sue E. Leurgans, Lisa L. Barnes, Jose M. Farfel, David A. Bennett   +6 more
doaj   +1 more source

Relationship of fasting glucose and longitudinal Alzheimer's disease imaging markers

Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2022
Introduction Fasting glucose increases with age and is linked to modifiable Alzheimer's disease risk factors such as cardiovascular disease and Type 2 diabetes (T2D).
Robyn A. Honea, Casey S. John, Zachary D. Green, Paul J. Kueck, Matthew K. Taylor, Rebecca J. Lepping, Ryan Townley, Eric D. Vidoni, Jeffery M. Burns, Jill K. Morris   +9 more
doaj   +1 more source

Identification of gene pathways implicated in Alzheimer's disease using longitudinal imaging phenotypes with sparse regression. [PDF]

, 2012
We present a new method for the detection of gene pathways associated with a multivariate quantitative trait, and use it to identify causal pathways associated with an imaging endophenotype characteristic of longitudinal structural change in the brains ...
Alzheimer's Disease Neuroimaging Initiative, Silver, Matt, Montana, Giovanni, Thompson, Paul M, Janousova, Eva, Thompson, Paul M., Hua, Xue   +6 more
core   +1 more source

Resting state cortical EEG rhythms in Alzheimer's disease: toward EEG markers for clinical applications: a review [PDF]

, 2012
The human brain contains an intricate network of about 100 billion neurons. Aging of the brain is characterized by a combination of synaptic pruning, loss of cortico-cortical connections, and neuronal apoptosis that provoke an age-dependent decline of ...
Lizio, Roberta, De Vico Fallani, Fabrizio, Fabrizio Vecchio, F. De Vico Fallani, Frisoni, Giovanni, Fabrizio De Vico Fallani, Giulio Verrienti, Giovanni Frisoni, Vecchio, Fabrizio, Rossini, Paolo M, G. Verrienti, P. M. Rossini, F. Vecchio, Verrienti, Giulio, Frisoni, Giovanni B., Paolo M. Rossini, Rossini, Paolo M., Babiloni, Claudio, Fde V. Fallani, Blinowska, Katarzyna, G. Frisoni, Rossini, Paolo Maria, Claudio Babiloni, K. Blinowska, Katarzyna Blinowska, Roberta Lizio   +25 more
core   +1 more source

Relation of neuropathology with cognitive decline among older persons without dementia

Frontiers in Aging Neuroscience, 2013
Objective: Although it is now widely accepted that dementia has a long preclinical phase during which neuropathology accumulates and cognition declines, little is known about the relation of neuropathology with the longitudinal rate of change in ...
Patricia eBoyle, Lei eYu, Robert eWilson, Julie eSchneider, David Alan Bennett   +4 more
doaj   +1 more source

Altered Expression of the CB1 Cannabinoid Receptor in the Triple Transgenic Mouse Model of Alzheimer's Disease [PDF]

, 2014
The endocannabinoid system has gained much attention as a new potential pharmacotherapeutic target in various neurodegenerative diseases, including Alzheimer's disease (AD).
Silvia Cianci, ROMANO, ADELE, Romano, A, M. r. Elphick, Gianluigi Vendemiale, Pace, Lorenzo, Elphick, Maurice R, Bedse, G, Angelo M. Lavecchia, Gaurav Bedse, GAETANI, SILVANA, VENDEMIALE, GIANLUIGI, LAVECCHIA, ANGELO MICHELE, @CORRESPONDING AUTHOR, Vendemiale, G, CIANCI, SILVIA, Pace Lorenzo, Lorenzo Federico Pace, Adele Romano, Gaetani, S, Tommaso Cassano, BEDSE, GAURAV, Lorenzo, P, Caterina Grillo, Cassano, T, Grillo, C, Laferla, Frank M, ALTIERI, Fabio, Elphick, MR, LaFerla, FM, Maurice R. Elphick, GRILLO, CATERINA, Silvana Gaetani, Frank M. LaFerla, F. m. Laferla, CASSANO, TOMMASO, Lavecchia, AM, Fabio Altieri, Altieri, F, Cianci, S   +39 more
core   +1 more source

Risk Aversion is Associated with Decision Making among Community-Based Older Persons

Frontiers in Psychology, 2012
Background: Risk aversion is associated with many important decisions among younger and middle aged persons, but the association of risk aversion and decision making has not been well studied among older persons who face some of the most significant ...
Patricia eBoyle, Lei eYu, Aron eBuchman, David eBennett   +3 more
doaj   +1 more source

ARIA in patients treated with lecanemab (BAN2401) in a phase 2 study in early Alzheimer's disease

Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2023
INTRODUCTION Lecanemab is a humanized immunoglobulin G1 (IgG1) monoclonal antibody that preferentially targets soluble aggregated Aβ species (protofibrils) with activity at amyloid plaques.
Lawrence S. Honig, Jerome Barakos, Shobha Dhadda, Michio Kanekiyo, Larisa Reyderman, Michael Irizarry, Lynn D. Kramer, Chad J. Swanson, Marwan Sabbagh   +8 more
doaj   +1 more source

Mitochondrial β-amyloid in Alzheimer's disease [PDF]

, 2011
This research is supported by Alzheimer's Research UK, the Wellcome Trust and the Biotechnology and Biological Sciences Research Council.It is well established that the intracellular accumulation of beta-amyloid is associated with Alzheimer’s disease and
Ainge, JA, James A. Ainge, Muirhead, Kirsty Elizabeth Adair, Gunn-Moore, FJ, Muirhead, KE, Laura Aitken, Aitken, Laura, Zoe E. Allen, Allen, Zoe Eleanor, Gunn-Moore, Frank J, Conway, Stuart, Frank J. Gunn-Moore, Allen, ZE, Borger, E, Aitken, L, Borger, Eva, Conway, SJ, Ainge, James Alexander, Kirsty E.A. Muirhead, Eva Borger, Stuart J. Conway   +20 more
core   +1 more source