Results 1 to 10 of about 14,146 (69)
EMBO Molecular Medicine, 2019 Failures in Alzheimer's disease (AD) drug trials highlight the need to further explore disease mechanisms and alterations of biomarkers during the development of AD.
Sebastian Palmqvist +11 more
doaj +2 more sources
Plasma Metabolomic Profiling Reveals Preliminary Biomarkers of Pork Quality Based on pH Value
Foods, 2022 This study aimed to identify biomarkers for pork quality evaluation. Firstly, the correlation between indicators of pork quality evaluation was investigated. The pH of pork meat at 45 min post slaughter showed a significant negative correlation with meat
Linyuan Shen +15 more
doaj +1 more source
Безопасность и риск фармакотерапии, 2023 Scientific relevance. Valproic acid (VPA) is a psychotropic medicinal product, which may be associated with serious adverse drug reactions (ADRs). While pharmacogenetics and pharmacometabolomics can significantly affect the safety of valproates, there ...
N. A. Shnayder +3 more
doaj +1 more source
Comparison of Plasma and Urine Biomarker Performance in Acute Kidney Injury.
PLoS ONE, 2015 BackgroundNew renal biomarkers measured in urine promise to increase specificity for risk stratification and early diagnosis of acute kidney injury (AKI) but concomitantly may be altered by urine concentration effects and chronic renal insufficiency ...
Gunnar Schley +9 more
doaj +1 more source
Clinical & Translational Immunology, 2021 Objectives Non‐sputum‐based tests to accurately identify active tuberculosis (TB) disease and monitor response to therapy are urgently needed. This study examined the biomarker capacity of a panel of plasma proteins alone, and in conjunction with a ...
Jessica L Pedersen +9 more
doaj +1 more source
Frontiers in Aging Neuroscience, 2018 Brain aging is a multifaceted process that remains poorly understood. Despite significant advances in technology, progress toward identifying reliable risk factors for suboptimal brain health requires realistically complex analytic methods to explain ...
Brandalyn C. Riedel +8 more
doaj +1 more source
Genetic plasma biomarkers associated with ischemic stroke
Exploration of Neuroscience, 2023 Aim: Stroke is one of the leading causes of death and disability worldwide. Plasma biomarkers have long been used to evaluate physiological or pathological processes and to make predictions about the outcome of stroke patients.
Mihai Andrei Ruscu +8 more
doaj +1 more source
Diagnostic Blood Biomarkers in Alzheimer’s Disease
Biomedicines, 2022 Potential biomarkers for Alzheimer’s disease (AD) include amyloid β1–42 (Aβ1–42), t-Tau, p-Tau181, neurofilament light chain (NFL), and neuroimaging biomarkers. Their combined use is useful for diagnosing and monitoring the progress of AD.
Jung Eun Park +15 more
doaj +1 more source
Frontiers in Immunology, 2023 BackgroundDysregulated immune responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are thought to underlie the progression of coronavirus disease 2019 (COVID-19) to severe disease.
Rachel MacCann +21 more
doaj +1 more source
Frontiers in Aging Neuroscience, 2021 Background: Alzheimer's disease (AD) is the most common type of dementia and has no effective treatment to date. It is essential to develop a minimally invasive blood-based biomarker as a tool for screening the general population, but the efficacy ...
Bin Jiao +38 more
doaj +1 more source