Results 11 to 20 of about 383,796 (264)

High Plasma sTNF-R1 Level Is Related to Loss of Natural HIV Control in Long-Term Elite Controllers

Frontiers in Cellular and Infection Microbiology, 2022
Human immunodeficiency virus-1 (HIV-1) elite controllers are heterogeneous due to different immunovirological features. We aimed to identify plasma biomarkers associated with loss of spontaneous HIV-1 control in long-term elite controllers (HIV-LTECs ...
Daniel Sepúlveda-Crespo, Norma Rallón, Norma Rallón, María José Muñoz-Gómez, Oscar Brochado-Kith, José Luis Jiménez, José Luis Jiménez, José Luis Jiménez, María Ángeles Muñoz-Fernández, María Ángeles Muñoz-Fernández, María Ángeles Muñoz-Fernández, María Ángeles Muñoz-Fernández, José M. Benito, José M. Benito, Salvador Resino   +14 more
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Plasma miRNAs as biomarkers for endometriosis [PDF]

Human Reproduction, 2019
Abstract STUDY QUESTION Can plasma miRNAs be used for the non-invasive diagnosis of endometriosis in infertile women? SUMMARY ANSWER miRNA-based diagnostic models for endometriosis failed the test of independent validation.
Vanhie, A, O, D, Peterse, D, Beckers, A, Cuéllar, A, Fassbender, A, Meuleman, C, Mestdagh, P, D’Hooghe, T   +8 more
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Inflammatory biomarkers in Alzheimer's disease plasma [PDF]

Alzheimer's & Dementia, 2019
AbstractIntroductionPlasma biomarkers for Alzheimer's disease (AD) diagnosis/stratification are a “Holy Grail” of AD research and intensively sought; however, there are no well‐established plasma markers.MethodsA hypothesis‐led plasma biomarker search was conducted in the context of international multicenter studies.
Morgan, Angharad R., Touchard, Samuel, Leckey, Claire, O'Hagan, Caroline, Nevado-Holgado, Alejo J., Barkhof, Frederik, Bertram, Lars, Blin, Olivier, Bos, Isabelle, Dobricic, Valerija, Engelborghs, Sebastiaan, Frisoni, Giovanni, Froelich, Lutz, Gabel, Silvey, Johannsen, Peter, Kettunen, Petronella, Koszewska, Iwona, Legido-Quigley, Cristina, Lleo, Alberto, Martinez-Lage, Pablo, Mecocci, Patrizia, Meersmans, Karen, Luis Molinuevo, Jose, Peyratout, Gwendoline, Popp, Julius, Richardson, Jill, Sala, Isabel, Scheltens, Philip, Streffer, Johannes, Soininen, Hikka, Tainta-Cuezva, Mikel, Teunissen, Charlotte, Tsolaki, Magda, Vandenberghe, Rik, Visser, Pieter Jelle, Vos, Stephanie, Wahlund, Lars-Olof, Wallin, Anders, Westwood, Sarah, Zetterberg, Henrik, Lovestone, Simon, Morgan, B. Paul, Bullmore, Edward T., Bhatti, Junaid, Chamberlain, Samuel J., Correia, Marta M., Crofts, Anna L., Dickinson, Amber, Foster, Andrew C., Kitzbichler, Manfred G., Knight, Clare, Lynall, Mary-Ellen, Maurice, Christina, O'Donnell, Ciara, Pointon, Linda J., Hyslop, Peter St George, Turner, Lorinda, Vertes, Petra, Widmer, Barry, Williams, Guy B., Morgan, B. Paul, Leckey, ClaireA., Morgan, Angharad R., O'Hagan, Caroline, Touchard, Samuel, Cavanagh, Jonathan, Deith, Catherine, Farmer, Scott, McClean, John, McColl, Alison, McPherson, Andrew, Scouller, Paul, Sutherland, Murray, Boddeke, H.WG.M. Erik, Richardson, Jill C., Khan, Shahid, Murphy, Phil, Parker, Christine A., Patel, Jai, Jones, Declan, de Boer, Peter, Kemp, John, Drevets, Wayne C., Nye, Jeffrey S., Wittenberg, Gayle, Isaac, John, Bhattacharya, Anindya, Carruthers, Nick, Kolb, Hartmuth, Pariante, Carmine M., Turkheimer, Federico, Barker, Gareth J., Byrom, Heidi, Cash, Diana, Cattaneo, Annamaria, Gee, Antony, Hastings, Caitlin, Mariani, Nicole, McLaughlin, Anna, Mondelli, Valeria, Nettis, Maria, Nikkheslat, Naghmeh, Randall, Karen, Sheridan, Hannah, Simmons, Camilla, Singh, Nisha, Van Loo, Victoria, Vicente-Rodriguez, Marta, Wood, Tobias C., Worrell, Courtney, Zajkowska, Zuzanna, Plath, Niels, Egebjerg, Jan, Eriksson, Hans, Gastambide, Francois, Adams, Karen Husted, Jeggo, Ross, Thomsen, Christian, Pederson, Jan Torleif, Campbell, Brian, Moller, Thomas, Nelson, Bob, Zorn, Stevin, O'Connor, Jason, Attenburrow, Mary Jane, Baird, Alison, Benjamin, Jithen, Clare, Stuart, Cowen, Philip, Huang, I-Shu Dante, Hurley, Samuel, Jones, Helen, Lovestone, Simon, Mada, Francisca, Nevado-Holgado, Alejo, Oladejo, Akintayo, Ribe, Elena, Smith, Katy, Vyas, Anviti, Hughes, Zoe, Balice-Gordon, Rita, Duerr, James, Piro, Justin R., Sporn, Jonathan, Perry, V. Hugh, Cleal, Madeleine, Fryatt, Gemma, Gomez-Nicola, Diego, Mancuso, Renzo, Reynolds, Richard, Harrison, Neil A., Cercignani, Mara, Clarke, Charlotte L., Hoskins, Elizabeth, Kohn, Charmaine, Murray, Rosemary, Wilcock, Lauren, Wlazly, Dominika   +157 more
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Plasma biomarkers for neuronal ceroid lipofuscinosis [PDF]

The FEBS Journal, 2015
The neuronal ceroid lipofuscinoses (NCLs) are a group of neurodegenerative genetic diseases that primarily affect children and have no known cure. A unified clinical rating scale for the juvenile form of NCL has been developed, although it has not been validated in other subtypes and does not give a true measure of the pathophysiological changes ...
Samantha L, Hersrud, Ryan D, Geraets, Krystal L, Weber, Chun-Hung, Chan, David A, Pearce   +4 more
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Protein profiling in plasma for biomarkers of seizure

Epilepsy Research, 2023
A biochemical way to measure seizures would greatly benefit epilepsy research and clinical follow-up. Short-term biomarkers like lactate exist, and interest in biomarkers representative of longer-term seizure burden is growing. In this exploratory study, we aimed to identify markers in blood plasma that differentiate persons with recent seizures from ...
Sarah Akel, Rakesh Kumar Banote, Fredrik Asztely, Johan Zelano   +3 more
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Seminal Plasma Proteomic Biomarkers of Oxidative Stress [PDF]

International Journal of Molecular Sciences, 2020
The prevalence of idiopathic male infertility is high, up to 75% of patients with abnormal sperm parameters. Hence, the research of its causes is mandatory. Oxidative stress (OS) can be responsible for male infertility in 30–80% of cases. In recent years, seminal plasma (SP) proteomics has developed as a useful tool to provide biomarkers of specific ...
Rossella Cannarella, Andrea Crafa, Federica Barbagallo, Laura M. Mongioì, Rosita A. Condorelli, Antonio Aversa, Aldo E. Calogero, Sandro La Vignera   +7 more
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Pharmacogenetics-Informed Pharmacometabolomics as an Innovative Approach to Assessing the Safety and Risk of Pharmacotherapy with Valproic Acid

Безопасность и риск фармакотерапии, 2023
Scientific relevance. Valproic acid (VPA) is a psychotropic medicinal product, which may be associated with serious adverse drug reactions (ADRs). While pharmacogenetics and pharmacometabolomics can significantly affect the safety of valproates, there ...
N. A. Shnayder, V. V. Grechkina, V. V. Arkhipov, R. F. Nasyrova   +3 more
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Plasma biomarkers in carbon monoxide poisoning [PDF]

Clinical Toxicology, 2010
The severity of acute carbon monoxide (CO) poisoning is often based on non-specific clinical criteria because there are no reliable laboratory markers. We hypothesized that a pattern of plasma protein values might objectively discern CO poisoning severity.
Stephen R, Thom, Veena M, Bhopale, Tatyana M, Milovanova, Kevin R, Hardy, Christopher J, Logue, David S, Lambert, Andrea B, Troxel, Kerri, Ballard, Dominic, Eisinger   +8 more
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Plasma gelsolin as a biomarker of inflammation [PDF]

Arthritis Research & Therapy, 2008
The prognostic implications of declining plasma gelsolin levels have been documented after a diverse variety of acute insults. Because gelsolin concentrations fall prior to the development of complications, a pathophysiological role for gelsolin depletion has been postulated in delayed multiorgan failure.
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Biomarkers of Alzheimer disease in plasma [PDF]

NeuroRX, 2004
Plasma and serum biochemical markers proposed for Alzheimer disease (AD) are based on pathophysiologic processes such as amyloid plaque formation [amyloid beta-protein (A beta), A beta autoantibodies, platelet amyloid precursor protein (APP) isoforms], inflammation (cytokines), oxidative stress (vitamin E, isoprostanes), lipid metabolism ...
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