Results 11 to 20 of about 14,295 (215)
Plasma circRNAs as Biomarkers in Cancer
Cancer Management and Research, 2021 The incidence and mortality of cancer are increasing each year. At present, the sensitivity and specificity of the blood biomarkers that were used in clinical practice are low, which make the detection rate of cancer decrease. With advances in bioinformatics and technology, some non-coding RNA as biomarkers can be easily detected through some ...
Qian Zhou +5 more
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Plasma biomarkers of mouse aging [PDF]
AGE, 2010 Normal aging is accompanied by a series of physiological changes such as gray hair, cataracts, reduced immunity, and increased susceptibility to disease. To identify novel biomarkers of normal aging, we analyzed plasma proteins of male mice longitudinally from 2 to 19 months of age.
Juan, Ding, John J, Kopchick
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Plasma miRNAs as biomarkers for endometriosis [PDF]
Human Reproduction, 2019 Abstract STUDY QUESTION Can plasma miRNAs be used for the non-invasive diagnosis of endometriosis in infertile women? SUMMARY ANSWER miRNA-based diagnostic models for endometriosis failed the test of independent validation.
Vanhie, A +8 more
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Protein profiling in plasma for biomarkers of seizure
Epilepsy Research, 2023 A biochemical way to measure seizures would greatly benefit epilepsy research and clinical follow-up. Short-term biomarkers like lactate exist, and interest in biomarkers representative of longer-term seizure burden is growing. In this exploratory study, we aimed to identify markers in blood plasma that differentiate persons with recent seizures from ...
Sarah Akel +3 more
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Plasma biomarkers for neuronal ceroid lipofuscinosis [PDF]
The FEBS Journal, 2015 The neuronal ceroid lipofuscinoses (NCLs) are a group of neurodegenerative genetic diseases that primarily affect children and have no known cure. A unified clinical rating scale for the juvenile form of NCL has been developed, although it has not been validated in other subtypes and does not give a true measure of the pathophysiological changes ...
Samantha L, Hersrud +4 more
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Plasma biomarkers in carbon monoxide poisoning [PDF]
Clinical Toxicology, 2010 The severity of acute carbon monoxide (CO) poisoning is often based on non-specific clinical criteria because there are no reliable laboratory markers. We hypothesized that a pattern of plasma protein values might objectively discern CO poisoning severity.
Stephen R, Thom +8 more
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Seminal Plasma Proteomic Biomarkers of Oxidative Stress [PDF]
International Journal of Molecular Sciences, 2020 The prevalence of idiopathic male infertility is high, up to 75% of patients with abnormal sperm parameters. Hence, the research of its causes is mandatory. Oxidative stress (OS) can be responsible for male infertility in 30–80% of cases. In recent years, seminal plasma (SP) proteomics has developed as a useful tool to provide biomarkers of specific ...
Rossella Cannarella +7 more
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Plasma gelsolin as a biomarker of inflammation [PDF]
Arthritis Research & Therapy, 2008 The prognostic implications of declining plasma gelsolin levels have been documented after a diverse variety of acute insults. Because gelsolin concentrations fall prior to the development of complications, a pathophysiological role for gelsolin depletion has been postulated in delayed multiorgan failure.
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Biomarkers of Alzheimer disease in plasma [PDF]
NeuroRX, 2004 Plasma and serum biochemical markers proposed for Alzheimer disease (AD) are based on pathophysiologic processes such as amyloid plaque formation [amyloid beta-protein (A beta), A beta autoantibodies, platelet amyloid precursor protein (APP) isoforms], inflammation (cytokines), oxidative stress (vitamin E, isoprostanes), lipid metabolism ...
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Frontiers in Aging Neuroscience, 2022 BackgroundPlasma-derived β-amyloid, tau, and neurodegeneration (ATN) biomarkers can accurately diagnose Alzheimer’s disease (AD) and predict its progression.
Qingling Sun +8 more
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