Results 21 to 30 of about 14,295 (215)

Effect of renal function on the diagnostic performance of plasma biomarkers for Alzheimer’s disease

open access: yesFrontiers in Aging Neuroscience, 2023
BackgroundSeveral blood-based biomarkers are promising to be used in the diagnosis of Alzheimer’s disease (AD) including Aβ42/40, p-tau181, and neurofilament light (NfL). The kidney is associated with the clearance of proteins.
Bin Zhang   +7 more
doaj   +1 more source

Dopamine in plasma – a biomarker for myofascial TMD pain? [PDF]

open access: yesThe Journal of Headache and Pain, 2016
Dopaminergic pathways could be involved in the pathophysiology of myofascial temporomandibular disorders (M-TMD). This study investigated plasma levels of dopamine and serotonin (5-HT) in patients with M-TMD and in healthy subjects.Fifteen patients with M-TMD and 15 age- and sex-matched healthy subjects participated.
Dawson, Andreas   +6 more
openaire   +6 more sources

CSF and plasma biomarkers for DLB [PDF]

open access: yesAlzheimer's & Dementia, 2020
AbstractBackgroundCSF biomarkers of amyloid and tau provide components of the A/T/N classification for AD and hold clinical prognostic value. They can help to identify how AD co‐pathology contributes to DLB. Alpha‐synuclein (a‐Syn) aggregation is a key pathogenic process in DLB, proposed to follow a staging system for spread of pathology.
Doug R. Galasko   +3 more
openaire   +1 more source

Early functional neuroimaging alterations in pTau217 biomarker-positive older adults

open access: yesFrontiers in Aging Neuroscience
IntroductionEarly identification of individuals with Alzheimer’s Disease (AD) is key to its successful management. In this regard, plasma biomarkers and functional magnetic resonance imaging alterations could represent useful triage tools for preclinical
Arianna Menardi   +41 more
doaj   +1 more source

Outcomes Based on Plasma Biomarkers for the Phase 3 CELESTIAL Trial of Cabozantinib versus Placebo in Advanced Hepatocellular Carcinoma

open access: yesLiver Cancer, 2021
Introduction: Cabozantinib, an inhibitor of MET, AXL, and VEGF receptors, significantly improved overall survival (OS) and progression-free survival (PFS) versus placebo in patients with previously treated advanced hepatocellular carcinoma (HCC). In this
Lorenza Rimassa   +14 more
doaj   +1 more source

Detection of lung allograft injury through a comprehensive multidisciplinary analysis of donor-derived cell-free DNA in plasma and bronchoalveolar lavage: a real-world single center experience

open access: yesFrontiers in Immunology
IntroductionPlasma donor-derived cell-free DNA (dd-cfDNA) is an emerging potential tool for diagnosing lung graft injury. This study explored the relevance of dd-cfDNA levels in different graft injuries thoroughly characterized after a well-established ...
Fiorella Calabrese   +17 more
doaj   +1 more source

Early Gestational Blood Markers to Predict Preeclampsia Complicating Gestational Diabetes Mellitus

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2023
Yan Xie,1 Wenni Zhou,1 Xiang Tao,2 Hui Lv,3 Zhongping Cheng1 1Department of Obstetrics and Gynecology, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai, 200072, People’s Republic of China; 2Department of Pathology ...
Xie Y, Zhou W, Tao X, Lv H, Cheng Z
doaj  

Plasma Biomarkers of HIV-associated Cognitive Disease [PDF]

open access: yesEBioMedicine, 2016
By controlling human immunodeficiency virus (HIV) replication and allowing recovery of immune system function, combination antiretroviral therapy (cART) has revolutionised the outlook for people-living-with-HIV (PLWH) to that of a chronic but manageable medical condition.
Winston, Alan, Underwood, Jonathan
openaire   +5 more sources

Chronic Inflammation and Altered Immune Responses in LongCOVID Associate with Neurological Manifestations and Accelerated Aging

open access: yesCells
There is a subgroup of people infected with the SARS-CoV-2 virus who manifest lingering sequelae (LongC), with neurological symptoms (nLongC). We recruited 86 COVID-19 volunteers, 35 of whom were fully recovered (Cov) and 51 who had neurological symptoms
Norina Tang   +3 more
doaj   +1 more source

High Plasma sTNF-R1 Level Is Related to Loss of Natural HIV Control in Long-Term Elite Controllers

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Human immunodeficiency virus-1 (HIV-1) elite controllers are heterogeneous due to different immunovirological features. We aimed to identify plasma biomarkers associated with loss of spontaneous HIV-1 control in long-term elite controllers (HIV-LTECs ...
Daniel Sepúlveda-Crespo   +14 more
doaj   +1 more source

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