Results 1 to 10 of about 8,411 (245)

Quinoline and Phthalimide Substituted Silicon Phthalocyanines as Multi-Target Inhibitors of Cholinesterases and Carbonic Anhydrases. [PDF]

J Biochem Mol Toxicol
Two novel axially substituted silicon phthalocyanines were synthesized and characterized. Compound 2a exhibited significantly enhanced inhibition of AChE, BChE, hCA I and hCA II, supported by molecular docking and SAR analysis, highlighting its potential as a multifunctional enzyme inhibitor with promising biological activity.
Ünlü S, Köksal Z, Kırboğa KK, Tuncel Elmalı F.   +3 more
europepmc   +2 more sources

Single but Not Combined In Vitro Exposure to Bisphenol A and Nanoplastics Affects the Cholinergic Function of the Ascidian Ciona robusta

Journal of Xenobiotics
Nanoplastics are known to represent a threat to marine ecosystems. Their combination with other contaminants of emerging concerns (CECs) may amplify ecotoxic effects, with unknown impacts on marine biodiversity.
Safa Melki, Emma Ferrari, Raja Ben Ahmed, Antonietta Spagnuolo, Ilaria Corsi   +4 more
doaj   +1 more source

Fiziološka uloga i klinički značaj serumske holinesteraze [PDF]

Vojnosanitetski Pregled, 2004
Balkanov Trajan, Konstantinović Slavko
doaj   +1 more source

Xanthones and Their Nitrogen and Sulfur Analogs in Alzheimer's Disease: Recent Progress Toward Multifunctional Therapeutics. [PDF]

ChemMedChem
Malafaia D, Melo L, Silva AMS, Albuquerque HMT.   +3 more
europepmc   +1 more source

Organ-Specific Targeted Phenolic Profiling, Antioxidant, and Enzyme-Inhibitory Activities of the Gypsophilous Endemic <i>Hedysarum pestalozzae</i>. [PDF]

Molecules
Aktürk Bozdemir E.
europepmc   +1 more source

The cholinesterases

Journal of Biological Chemistry, 1991
openaire   +2 more sources

Design, Synthesis, In Vitro and In Vivo Evaluation of Novel Anti-Alzheimer's (1<i>E</i>,4<i>E</i>)-1,5-Bis[(het)aryl]penta-1,4-dien-3-one Derivatives. [PDF]

Pharmaceuticals (Basel)
Mendes GO, Bento LDP, Oliveira TM, Barbosa DB, Tsui GS, Gomes EN, Sales RO, Rocha MSC, Silva MPD, Oliveira TA, Maia EHB, Falkoski DL, Marra IFS, Andrade LSM, Mendes LCVP, Fonseca BS, Oliveira LMG, Silva VDAD, Carvalho PB, Silva AMD, Taranto AG, Damázio LCM, Valle MS, Leite FHA.   +23 more
europepmc   +1 more source

Profiling arbutin as a potent cholinesterase and GSK-3β inhibitor and evaluating its cytotoxicity in SH-SY5Y cells for Alzheimer's disease therapy. [PDF]

Turk J Biol
Tarbiat S, Bal T, Gülmez D.
europepmc   +1 more source

Electrochemical Biosensor-Based Evaluation of Cholinergic Biomarkers in Experimental Nephropathy. [PDF]

Anal Chem
Butkevicius M, Sakinyte-Urbikiene I, Seniuk I, Galuzinska L, Lytkin D, Razumiene J.   +5 more
europepmc   +1 more source

Evolution of Multitarget Strategies for Alzheimer's Disease: From Cholinergic Inhibition to Network-Oriented Therapeutic Design (2006-2025). [PDF]

Pharmaceuticals (Basel)
Mella J, Vega-Muñoz A, Soto M, Moraga D, Campanini-Salinas J, Sandoval-Obando E, Contreras-Barraza N, Salazar-Sepúlveda G, Salas-Guzmán N, Carabantes-Silva R, Mellado M.   +10 more
europepmc   +1 more source