Results 31 to 40 of about 12,810 (265)
Anti-Bladder Cancer and Anti-Alzheimer Properties of Bavachin and Bavachinin as Natural Compounds with Molecular Docking and Dynamic Studies: In Vitro and in Silico Studies [PDF]
Iranian Journal of Chemistry & Chemical EngineeringNaturally occurring substances are crucial for both the treatment and prevention of many types of cancer. Currently in therapeutic usage are over 100 naturally occurring chemicals derived from plants and animals. The symptomatic management of Alzheimer’s
Yongqing Zheng +5 more
doaj +1 more source
Comparison of the cost‐effectiveness of a computer‐assisted learning program with a tutored demonstration to teach intestinal motility to medical students [PDF]
, 1995 Computer‐based simulations of undergraduate experiments in pharmacology and physiology may offer a cost‐effective alternative to the traditional live laboratory for some students, for whom laboratory skills are less important.
Dewhurst, D. G., Leathard, H. L.
core +2 more sources
Molecules, 2022 Alzheimer’s disease (AD) is a complex disorder characterized by impaired neurotransmission in cholinergic and monoaminergic neurons, which, in combination with the accumulation of misfolded proteins and increased oxidative stress, leads to the typical ...
Óscar M. Bautista-Aguilera +6 more
doaj +1 more source
Molecules, 2020 It is estimated that 50 million people in the world live with dementia, 60–70% of whom suffer from Alzheimer’s disease (AD). Different factors are involved in the development of AD, including a reduction in the cholinergic neurotransmission level.
Raúl Moreno +7 more
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Acetylcholinesterase Involvement in Apoptosis [PDF]
, 2012 To date, more than 40 different types of cells from primary cultures or cell lines have shown AChE expression during apoptosis and after the induction apoptosis by different stimuli. It has been well-established that increased AChE expression or activity
Xue-Jun Zhang, David S. Greenberg
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Frontiers in Molecular Neuroscience, 2019 Background: A fundamental question in Alzheimer’s disease (AD) is whether amyloid-β (Aβ) peptides and their deposition in the brain signify a direct pathological role or they are mere outcome of the disease pathophysiological events affecting neuronal ...
Erica Lana +6 more
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Anticholinesterase Activities of Different Solvent Extracts of Brewer’s Spent Grain
Foods, 2021 Cholinesterases, involved in acetylcholine catabolism in the central and peripheral nervous system, have been strongly linked with neurodegenerative diseases. Current therapeutic approaches using synthetic drugs present several side effects. Hence, there
Rares I. Birsan +3 more
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PlantsHieronymiella peruviana, a recently described endemic species from southern Peru, belongs to the Amaryllidaceae family and is known for its diversity of alkaloids.
Olimpia Llalla-Cordova +6 more
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Esterases of the flounder (Platichthys flesus, Pleuronectidae, Teleostei) : development of an identification protocol using starch gel electrophoresis and characterization of loci [PDF]
, 1990 Fish esterases are among the most difficult enzymes to identify using starch gel electrophoresis because of the many loci that are simultaneously active, and especially because of duplication phenomena, satellite bands, and stain trails. In an attempt to
Berrebi, P. +3 more
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Advanced Science, EarlyView.We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong +8 more
wiley +1 more source