Results 31 to 40 of about 4,982 (202)
Advanced Science, EarlyView.Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa +11 more
wiley +1 more source
In vitro inhibitory effects of selected anticholinesterase insecticides on human plasma and erythrocyte cholinesterases and their thermal reactivation [PDF]
المجلة العراقية للصيدلة, 2010 The inhibitory effect of a number of locally used organophosphorus and carbamate insecticides on human plasma and erythrocyte were examined in vitro by using the modified electrometric method for determination of cholinesterase (ChE) activity.
Omer A.H. Ahmed
doaj +1 more source
Crystals, 2021 Alzheimer’s disease (AD) causes dementia and continuous damage to brain cells. Cholinesterase inhibitors can alleviate the condition by increasing communication between the nerve cells and reducing the risk of dementia.
Muhammad Jamil +9 more
doaj +1 more source
Translational Gap in Biomarker Discovery: Tumor Surface Markers Rarely Mirror Circulating Levels
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Background Tumor‐associated cell surface proteins are frequently proposed as circulating biomarkers for colorectal cancer (CRC) based on their high tumor expression. However, many candidates identified through tissue‐based analyses fail to translate into clinically useful biomarkers.
Junko Mukohyama +9 more
wiley +1 more source
Effect of DBS detergent on activity of some enzymes of young carp (Cyprinus carpio L.) in brain, gills, and serum [PDF]
Acta Ichthyologica et Piscatoria, 1977 Effects of DBS (natrium dodecyl-benzene-sulphonate) on the activity of ATP-ases and cholinesterases of autumn young carp brain, gills, and serum were studied. On the second day of the brain ATP-ases activity was found to increase by ca 120%.
M.K. Jurkowski
doaj +3 more sources
Arthritis &Rheumatology, EarlyView.Objective Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Patients with lupus and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu +2 more
wiley +1 more source
Anti-Bladder Cancer and Anti-Alzheimer Properties of Bavachin and Bavachinin as Natural Compounds with Molecular Docking and Dynamic Studies: In Vitro and in Silico Studies [PDF]
Iranian Journal of Chemistry & Chemical EngineeringNaturally occurring substances are crucial for both the treatment and prevention of many types of cancer. Currently in therapeutic usage are over 100 naturally occurring chemicals derived from plants and animals. The symptomatic management of Alzheimer’s
Yongqing Zheng +5 more
doaj +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi +6 more
wiley +1 more source
Applied Sciences, 2021 Nineteen tosylated acyl hydrazone derivatives were synthesized, and their inhibitory activities against monoamine oxidases (MAOs), acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and β-secretase (BACE-1) were evaluated.
Hasan Erdinç Sellitepe +11 more
doaj +1 more source
iMetaMed, EarlyView.Combining clinical data with serum proteomics and metabolomics, the HGB–CAPZB–acetic acid model was developed as a potential diagnostic index to distinguish the active and stable stages of Helicobacter pylori‐infected chronic gastritis, and the related mechanism was explored through multi‐omics.
Tiantong Jiang +7 more
wiley +1 more source