Results 21 to 30 of about 8,411 (245)
Molecules, 2021 Cognitive decline in dementia is associated with deficiency of the cholinergic system. In this study, five mono-carbonyl curcumin analogs were synthesized, and on the basis of their promising in vitro anticholinesterase activities, they were further ...
Haya Hussain +12 more
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Molecules, 2020 Eight compounds were isolated from the roots of Glycyrrhiza uralensis and tested for cholinesterase (ChE) and monoamine oxidase (MAO) inhibitory activities.
Geum Seok Jeong +6 more
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Exploring the enzyme inhibitory properties of Antarctic algal extracts
Türk Biyokimya Dergisi, 2023 Marine organisms obtained from Antarctica are prominent sources for many important activities. Algae are known for adapting to various adverse environmental conditions and for producing secondary metabolites with various biological activities. This study
Gözcelioğlu Bülent +3 more
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Counteracting poisoning with chemical warfare nerve agents
Arhiv za Higijenu Rada i Toksikologiju, 2020 Phosphylation of the pivotal enzyme acetylcholinesterase (AChE) by nerve agents (NAs) leads to irreversible inhibition of the enzyme and accumulation of neurotransmitter acetylcholine, which induces cholinergic crisis, that is, overstimulation of ...
Hrvat Nikolina Maček, Kovarik Zrinka
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Noncholinergic functions of cholinesterases [PDF]
, 1993 Cholinesterases (acetylcholinesterase and butyrylcholinesterase) exhibit additional catalytic activities apart from their well-known action in hydrolyzing choline esters.
Bhanumathy, C. D. +1 more
core +2 more sources
Foods, 2023 A sensitive and robust electrochemical cholinesterase-based sensor was developed to detect the quaternary ammonium (QAs) biocides most frequently found in agri-food industry wash waters: benzalkonium chloride (BAC) and didecyldimethylammonium chloride ...
Lynn Mouawad +3 more
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Molecules, 2020 It is estimated that 50 million people in the world live with dementia, 60–70% of whom suffer from Alzheimer’s disease (AD). Different factors are involved in the development of AD, including a reduction in the cholinergic neurotransmission level.
Raúl Moreno +7 more
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Frontiers in Molecular Neuroscience, 2019 Background: A fundamental question in Alzheimer’s disease (AD) is whether amyloid-β (Aβ) peptides and their deposition in the brain signify a direct pathological role or they are mere outcome of the disease pathophysiological events affecting neuronal ...
Erica Lana +6 more
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Molbank, 2020 As ferulic acid was reported to be involved in novel potential mechanisms associated with Alzheimer’s disease (AD) therapy, five closely related phenethyl esters and amide of this natural product were synthesized and screened for their free radicals ...
Ayyoub Selka +3 more
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Fisheries and Aquatic Sciences, 2022 Anti-cholinesterase (ChE)s are commonly prescribed as the symptomatic treatment of Alzheimer’s disease. They are applied to prevent the breakdown of neurotransmitter acetylcholine (ACh) that bind to muscarinic and ...
Jun-Rui Pang +5 more
doaj +1 more source