Results 11 to 20 of about 8,411 (245)

In Silico Docking and In Vitro Approaches towards BACE1 and Cholinesterases Inhibitory Effect of Citrus Flavanones

Molecules, 2018
Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease, distinctively characterized by senile plaques, neurofibrillary tangles, and synaptic loss, finally resulting in neuronal death.
Kumju Youn, Jinhyuk Lee, Mira Jun
exaly   +3 more sources

Presence of cholinesterases in Echinococcus granulosus protoscolices

Parasite, 2000
Cholinesterases were detected in protoscolices of Echinococcus granulosus spectrophotometrically and electrophoretically. To characterize these activities as acetylcholinesterases or pseudocholinesterases, BW284C51 and the organophosphate anthelmintic ...
Giménez-Pardo C., Ros Moreno R.M., De Armas-Serra C., Rodriguez-Caabeiro F.   +3 more
doaj   +3 more sources

Attenuation of Spatial Memory in 5xFAD Mice by Halting Cholinesterases, Oxidative Stress and Neuroinflammation Using a Cyclopentanone Derivative

Pharmaceuticals, 2020
Alzheimer’s disease (AD) is an irreversible and chronic neurological disorder that gradually destroys memory and thinking skills. The research study was designed to investigate the underlying molecular signaling involved in the neuroprotective effects of
Muhammad Amin, Muhammad Akram, Gowhar Ali   +2 more
exaly   +3 more sources

Cholinesterase Research [PDF]

Biomolecules, 2021
Cholinesterases are fundamental players in the peripheral and central nervous systems [...]
Jan Korabecny, Ondrej Soukup
openaire   +3 more sources

Evaluation of selected carotenoids of Lycopersicon esculentum variants as therapeutic targets for ‘Alzheimer’s disease: an in silico approach

BMC Molecular and Cell Biology, 2021
The seriousness and menace of the worldwide weight of ‘Alzheimer’s disease have been related to a few factors, which incorporate antioxidant system depletion, mutation of proteins, and high expression of cholinesterases due to aging, environmental ...
Olalekan Olanrewaju Bakare, Adewale Oluwaseun Fadaka, Musa Oyebowale Akanbi, Kolajo Adedamola Akinyede, Ashwil Klein, Marshall Keyster   +5 more
doaj   +1 more source

Ultrasound-Assisted Synthesis of Piperidinyl-Quinoline Acylhydrazones as New Anti-Alzheimer’s Agents: Assessment of Cholinesterase Inhibitory Profile, Molecular Docking Analysis, and Drug-like Properties

Molecules, 2023
Alzheimer’s disease (AD) is one of the progressive neurological disorders and the main cause of dementia all over the world. The multifactorial nature of Alzheimer’s disease is a reason for the lack of effective drugs as well as a basis for the ...
Rubina Munir, Sumera Zaib, Muhammad Zia-ur-Rehman, Nadia Hussain, Faryal Chaudhry, Muhammad Tayyab Younas, Fatima Tuz Zahra, Zainab Tajammul, Noman Javid, Ayed A. Dera, Hanan A. Ogaly, Imtiaz Khan   +11 more
doaj   +1 more source

Mangifera indica ‘Namdokmai’ Prevents Neuronal Cells from Amyloid Peptide Toxicity and Inhibits BACE-1 Activities in a Drosophila Model of Alzheimer’s Amyloidosis

Pharmaceuticals, 2022
Alzheimer’s disease (AD) is a progressive neurological illness with few effective treatments. Thus, ameliorating the effects of AD using natural products has attracted global attention with promising efficacy and safety.
Piya Temviriyanukul, Suwapat Kittibunchakul, Piyapat Trisonthi, Thanit Kunkeaw, Woorawee Inthachat, Dalad Siriwan, Uthaiwan Suttisansanee   +6 more
doaj   +1 more source

In-Vitro, In-Vivo, Molecular Docking and ADMET Studies of 2-Substituted 3,7-Dihydroxy-4H-chromen-4-one for Oxidative Stress, Inflammation and Alzheimer’s Disease

Metabolites, 2022
Plants’ bioactives are well-known safe drugs for vital diseases. Flavones and Flavonoid-rich dietary supplements are known to exhibit neuroprotective potential.
Mater H. Mahnashi, Mohammed Abdulrahman Alshahrani, Mohammed H. Nahari, Syed Shams ul Hassan, Muhammad Saeed Jan, Muhammad Ayaz, Farhat Ullah, Osama M. Alshehri, Mohammad Ali Alshehri, Umer Rashid, Abdul Sadiq   +10 more
doaj   +1 more source

The Role of Cholinesterases in Post-Exercise HRV Recovery in University Volleyball Players

Applied Sciences, 2021
Some studies show interest in measuring heart rate variability (HRV) during post-exercise recovery. It is known that the parasympathetic system is relevant during this process, where one of the factors of this modulation is the interaction of ...
José Raúl Hoyos-Flores, Blanca R. Rangel-Colmenero, Zeltzin N. Alonso-Ramos, Myriam Z. García-Dávila, Rosa M. Cruz-Castruita, José Naranjo-Orellana, Germán Hernández-Cruz   +6 more
doaj   +1 more source

Kinetics of human and horse sera cholinesterases inhibition with solanaceous glycoalkaloids: Study by potentiometric biosensor

, 2006
International audienceThe kinetics of inhibition of human and horse sera butyryl cholinesterases by solanaceous glycoalkaloids alpha-solanine, alpha-chaconine and tomatine has been studied by means of a potentiometric biosensor based on pH-sensitive ...
Arkhypova, Valentyna, N., Dzyadevych, Sergei, V., Jaffrezic-Renault, Nicole, Benilova, Iryna, V., Martelet, Claude, Soldatkin, Alexey, P.   +5 more
core   +8 more sources