Results 51 to 60 of about 8,411 (245)
Advanced Science, EarlyView.Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa +11 more
wiley +1 more source
Advanced Science, EarlyView.Two‐photon calcium imaging in behaving 5xFAD mice reveals early CA1 coding deficits before behavioral decline. Task‐related place cell activity and splitter cell trajectory coding are impaired, with reduced retrospective dominance and greater prospective weighting.
Yimei Li +8 more
wiley +1 more source
Survey of Major Points of Interest About Reactions of Cholinesterases [PDF]
, 1975 Three areas of current interest and activity in the study of the cholinesterases have been chosen for comment: Aging of phosphorylated cholinesterases.
Aldridge, W. N.
core +1 more source
Anti-Bladder Cancer and Anti-Alzheimer Properties of Bavachin and Bavachinin as Natural Compounds with Molecular Docking and Dynamic Studies: In Vitro and in Silico Studies [PDF]
Iranian Journal of Chemistry & Chemical EngineeringNaturally occurring substances are crucial for both the treatment and prevention of many types of cancer. Currently in therapeutic usage are over 100 naturally occurring chemicals derived from plants and animals. The symptomatic management of Alzheimer’s
Yongqing Zheng +5 more
doaj +1 more source
Effect of DBS detergent on activity of some enzymes of young carp (Cyprinus carpio L.) in brain, gills, and serum [PDF]
Acta Ichthyologica et Piscatoria, 1977 Effects of DBS (natrium dodecyl-benzene-sulphonate) on the activity of ATP-ases and cholinesterases of autumn young carp brain, gills, and serum were studied. On the second day of the brain ATP-ases activity was found to increase by ca 120%.
M.K. Jurkowski
doaj +3 more sources
Phenolic Profiling and Bioactivity Evaluation of Stachys aleurites Extracts: LC-ESI-MS/MS Characterization, Antioxidant Capacity, and Enzyme Inhibitory Potential. [PDF]
Chem BiodiversSolvent polarity shapes the phytochemical and bioactivity profile of Stachys aleurites. Methanol extraction enriches phenolics, especially verbascoside and chlorogenic acid, and enhances antioxidant and enzyme inhibitory activities, whereas the aqueous extract shows selective metal‐chelating and BChE inhibitory potential. ABSTRACT Natural products rich
Solmaz FOK, Sarikurkcu C, Tepe B.
europepmc +2 more sources
Applied Sciences, 2021 Nineteen tosylated acyl hydrazone derivatives were synthesized, and their inhibitory activities against monoamine oxidases (MAOs), acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and β-secretase (BACE-1) were evaluated.
Hasan Erdinç Sellitepe +11 more
doaj +1 more source
Arthritis &Rheumatology, EarlyView.Objective Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Patients with lupus and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu +2 more
wiley +1 more source
On novel functions of cholinesterases [PDF]
, 2006 The non-specificity of cholinesterases to cholinergic innervated tissues, their early onset during embryogenesis of many organisms, and their non-cholinolytic aryl acylamidase activity, indicate that these enzymes are involved with physiological ...
Allebrandt, Karla Viviani
core
ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi +6 more
wiley +1 more source